Zobrazeno 1 - 10
of 813
pro vyhledávání: '"Nesland Jahn M"'
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 201 (2012)
Abstract Background To study whether hypoxia influences the stem-like properties of ovarian cancer cells and their biological behavior under hypoxia. Method Ovarian cancer cell lines ES-2 and OVCAR-3 were cultivated in different oxygen tensions for p
Externí odkaz:
https://doaj.org/article/69646cad2cb94cbb92974ac03f8056bb
Autor:
Wang Junsheng, Yang Guanrui, He Wei, Wang Zhihui, Wang Zhong, Nesland Jahn M, Holm Ruth, Suo Zhenhe
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 352 (2010)
Abstract Background Glutathione S-transferase pi (GST pi) is a subgroup of GST family, which provides cellular protection against free radical and carcinogenic compounds due to its detoxifying function. Expression patterns of GST pi have been studied
Externí odkaz:
https://doaj.org/article/e70b0b86989742689088d62f95605f8f
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 233 (2010)
Abstract Background CDC25 phosphatases are important regulators of the cell cycle. Their abnormal expression detected in a number of tumors implies that their dysregulation is involved in malignant transformation. However, the role of CDC25s in vulva
Externí odkaz:
https://doaj.org/article/1b9456747ee94ffbbdf3ebdc4ed3c2c7
Autor:
Shou Chengcao, Fan Qingxia, Wang Qi, Wang Zhihui, He Wei, Wang Junsheng, Giercksky Karl-Erik, Nesland Jahn M, Suo Zhenhe
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 426 (2009)
Abstract Background HIWI, the human homologue of Piwi family, is present in CD34+ hematopoietic stem cells and germ cells, but not in well-differentiated cell populations, indicating that HIWI may play an impotent role in determining or maintaining s
Externí odkaz:
https://doaj.org/article/b4110eb5aef441a4aed83aa170f00899
Autor:
Suo Zhenhe, Tropè Claes G, Wang Zhihui, Trøen Gunhild, Yang Guanrui, Nesland Jahn M, Holm Ruth
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 308 (2008)
Abstract Background 14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. How
Externí odkaz:
https://doaj.org/article/377ebead1d0543cb8cadf42a92f747b2
Autor:
Tropé Claes G, Silins Ilvars, Ahlquist Terje, Lothe Ragnhild A, Wu Qinghua, Micci Francesca, Nesland Jahn M, Suo Zhenhe, Lind Guro E
Publikováno v:
Molecular Cancer, Vol 6, Iss 1, p 45 (2007)
Abstract Background The epigenetics of ovarian carcinogenesis remains poorly described. We have in the present study investigated the promoter methylation status of 13 genes in primary ovarian carcinomas (n = 52) and their in vitro models (n = 4; ES-
Externí odkaz:
https://doaj.org/article/128dc90eb4464ebcbe72c983994a7540
Autor:
Myklebost Ola, Nesland Jahn M, Brandal Lin T, Meling Gunn I, Diep Chieu B, Lind Guro E, Kleivi Kristine, Rognum Torleiv O, Giercksky Karl-Erik, Skotheim Rolf I, Lothe Ragnhild A
Publikováno v:
Molecular Cancer, Vol 6, Iss 1, p 2 (2007)
Abstract Background Despite the fact that metastases are the leading cause of colorectal cancer deaths, little is known about the underlying molecular changes in these advanced disease stages. Few have studied the overall gene expression levels in me
Externí odkaz:
https://doaj.org/article/063f9c713988469398bda4c688fa0381
Autor:
Nesland Jahn M, Dumeaux Vanessa, Wang Yun, Kringen Pedro, Kristensen Gunnar, Borresen-Dale Anne-Lise, Dorum Anne
Publikováno v:
BMC Cancer, Vol 5, Iss 1, p 134 (2005)
Abstract Background Ovarian carcinomas from 30 BRCA1 germ-line carriers of two distinct high penetrant founder mutations, 20 carrying the 1675delA and 10 the 1135insA, and 100 sporadic cases were characterized for somatic mutations in the TP53 gene.
Externí odkaz:
https://doaj.org/article/b7d4d34489d94430aa6e6897773644bc
Autor:
Tropè Claes G, Givant-Horwitz Vered, Goldberg Iris, Berner Aasmund, Risberg Björn, Flørenes Vivi, Reich Reuven, Skrede Martina, Davidson Ben, Schaner Marci E, Kristensen Gunnar B, Nesland Jahn M, Børresen-Dale Anne-Lise
Publikováno v:
Molecular Cancer, Vol 4, Iss 1, p 26 (2005)
Abstract Background While numerous studies have characterized primary ovarian tumors, little information is available regarding expression patterns of metastatic sites of this cancer. To define sets of genes that distinguish primary and metastatic ov
Externí odkaz:
https://doaj.org/article/895564ae701148f7be95243205807193
Autor:
Giercksky Karl-Erik, Nesland Jahn M, Eknæs Mette, Wiig Johan N, Thorstensen Lin, Teixeira Manuel R, Diep Chieu B, Johansson Bertil, Lothe Ragnhild A
Publikováno v:
Molecular Cancer, Vol 3, Iss 1, p 6 (2004)
Abstract Background Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths in the Western world, and despite the fact that metastases are usually the ultimate cause of deaths, the knowledge of the genetics of advanced stage
Externí odkaz:
https://doaj.org/article/b48479ac843047b4a75db72e820878ea