Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nesibe Peker"'
Autor:
Nesibe Peker, Johan Vande Voorde
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/fc3f8299914e4f06822ea3b64093c4f7
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Parkinson’s Disease (PD) is a chronic and progressive neurodegenerative disease manifesting itself with tremors, muscle stiffness, bradykinesia, dementia, and depression. Mutations of mitochondrial E3 ligase, PARKIN, have been associated w
Externí odkaz:
https://doaj.org/article/869a611056d64296a5c68c52f4c489b5
Autor:
Nur Mehpare Kocaturk, Nesibe Peker, Karin Eberhart, Yunus Akkoc, Gamze Deveci, Joern Dengjel, Devrim Gozuacik
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-15 (2022)
Abstract Autophagy is an evolutionarily conserved eukaryotic cellular mechanism through which cytosolic fragments, misfolded/aggregated proteins and organelles are degraded and recycled. Priming of mitochondria through ubiquitylation is required for
Externí odkaz:
https://doaj.org/article/4c0b871a164c40d997c2cd1c55e069a3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Primary cancer cells exert unique capacity to disseminate and nestle in distant organs. Once seeded in secondary sites, cancer cells may enter a dormant state, becoming resistant to current treatment approaches, and they remain silent until
Externí odkaz:
https://doaj.org/article/3e685cae02274edbaadafc3622cb10e0
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metastasis and relapse account for the great majority of cancer-related deaths. Most metastatic lesions are micro metastases that have the capacity to remain in a non-dividing state called “dormancy” for months or even years. Commonly used antica
Externí odkaz:
https://doaj.org/article/721654100ded46b185550fa3e9795ffa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Primary cancer cells exert unique capacity to disseminate and nestle in distant organs. Once seeded in secondary sites, cancer cells may enter a dormant state, becoming resistant to current treatment approaches, and they remain silent until they reac
Publikováno v:
American Journal of Physiology-Cell Physiology
G protein-coupled receptor kinase 2 (GRK2) is an important protein involved in β-adrenergic receptor desensitization. In addition, studies have shown GRK2 can modulate different metabolic processes in the cell. For instance, GRK2 has been recently s
Publikováno v:
NPJ Parkinson's Disease
Parkinson's Disease (PD) is a chronic and progressive neurodegenerative disease manifesting itself with tremors, muscle stiffness, bradykinesia, dementia, and depression. Mutations of mitochondria! E3 ligase, PARKIN, have been associated with juvenil
Autor:
Nesibe Peker, Devrim Gozuacik
Publikováno v:
Journal of molecular biology. 432(8)
Cells of an organism face with various types of insults during their lifetime. Exposure to toxins, metabolic problems, ischaemia/reperfusion, physical trauma, genetic diseases, neurodegenerative diseases are among the conditions that trigger cellular
Publikováno v:
American journal of physiology. Cell physiology. 315(2)
Parkinson’s disease is a neurodegenerative disease characterized by tremors, muscle stiffness, and muscle weakness. Molecular genetic analysis has confirmed that mutations in PARKIN and PINK1 genes, which play major roles in mitochondrial quality c