Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Neshika Samarasekera"'
Autor:
Caoimhe Kirby, Lotte Sondag, Jack Barrington, Floris H.B.M. Schreuder, James J.M. Loan, Catharina J.M. Klijn, Barry W. McColl, Neshika Samarasekera, Rustam Al-Shahi Salman
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background Currently, there are no specific medical treatments for intracerebral haemorrhage (ICH), but the inflammatory response may provide a potential route to treatment. Given the known effects of acute brain injury on peripheral immunity, we hyp
Externí odkaz:
https://doaj.org/article/4403a37aa48e40b09d8795b6052356e3
Autor:
Tom J. Moullaali, Rachel Walters, Mark Rodrigues, Neshika Samarasekera, Jose Bernal, Xia Wang, Catherine Humphreys, Joanna M. Wardlaw, Andrew Farrall, Colin Smith, Craig S. Anderson, Rustam Al-Shahi Salman, Brian McKinstry
Publikováno v:
Frontiers in Stroke, Vol 2 (2023)
IntroductionThe role of systolic blood pressure (SBP) variability in the pathogenesis of cerebral amyloid angiopathy (CAA) as an underlying cause of intracerebral hemorrhage (ICH) is unknown. We studied SBP variability before ICH according to CAA sev
Externí odkaz:
https://doaj.org/article/858093f7cde94ed489980126ef063f51
Guillain-Barré syndrome following SARS-CoV-2 vaccination in the UK: a prospective surveillance study
Autor:
Peter M Fernandes, Louise Wiblin, Tom Solomon, Jonathan Evans, Benedict D Michael, Bart C Jacobs, Daniel Whittam, Harry Tucker, Emma Tallantyre, David P Breen, Neshika Samarasekera, Kathryn Knight, Martin Zeidler, Julia Stowe, Sonja E Leonhard, Victoria Harris, Helen McDonald, Kathryn Brennan, Eva Maria Hodel, Ralph Gregory, Katy Murray, Simon Shields, Andreas C Themistocleous, Stephen Sawcer, CLARE GALTON, Orla Tuohy, Stephan Hinze, Jacob Roelofs, James Holt, Julian Furby, Bhagteshwar Singh, Lucy Hogg, Scott Ramsay, Shue Jun Cheng, Andrew McHattie, Arina A Tamborska, Taylor Watson-Fargie, Caroline Morrice, Christopher M Allen, Gionathan Amante, Ana Carrilho Romeiro, Ginette Crossingham, Jon Evison, Alifa Isaacs-Itua, Mireia Moragas Garrido, Shelby Ramsamy, Pyae Phyo San, Robyn Terry
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 2 (2022)
Objective To investigate features of Guillain-Barré syndrome (GBS) following SARS-CoV-2 vaccines and evaluate for a causal link between the two.Methods We captured cases of GBS after SARS-CoV-2 vaccination through a national, open-access, online sur
Externí odkaz:
https://doaj.org/article/520eb838f5a64a8a9e594d4a133f5181
Autor:
Colin Smith, Rustam Al-Shahi Salman, Karina McDade, Edward Christopher, Neshika Samarasekera, James J M Loan, Jamie Rose, Jack Barrington, Jeremy Hughes
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 1 (2022)
Aims Pharmacological activation of the antioxidative transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) improves outcomes in experimental models of intracerebral haemorrhage (ICH). However, the Nrf2 pathway has not been previousl
Externí odkaz:
https://doaj.org/article/3cfe53a053a74e8583f76664a1754f3e
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180923 (2017)
BACKGROUND:We sought to summarize Computed Tomography (CT)/Magnetic Resonance Imaging (MRI) features of intracerebral hemorrhage (ICH) associated with cerebral amyloid angiopathy (CAA) in published observational radio-pathological studies. METHODS:In
Externí odkaz:
https://doaj.org/article/2ff04dfa35e74cb791c8801e0fa01810
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0187386 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0180923.].
Externí odkaz:
https://doaj.org/article/b0d2e08660554f2ea3f6aba2e6b20ffd
Autor:
Neshika Samarasekera, Christine Lerpiniere, Arthur F Fonville, Andrew J Farrall, Joanna M Wardlaw, Philip M White, Antonia Torgersen, James W Ironside, Colin Smith, Rustam Al-Shahi Salman, Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135043 (2015)
BACKGROUND:Spontaneous intracerebral haemorrhage is a devastating form of stroke and its incidence increases with age. Obtaining brain tissue following intracerebral haemorrhage helps to understand its cause. Given declining autopsy rates worldwide,
Externí odkaz:
https://doaj.org/article/227c17ca88eb45b6b217e2ba38781ea3
Publikováno v:
PLoS Medicine, Vol 7, Iss 10, p e1000353 (2010)
Externí odkaz:
https://doaj.org/article/78942f063e224d1e875c418da421a8ee
Autor:
Maaike P Cliteur, Lotte Sondag, Laura Cunningham, Rustam Al-Shahi Salman, Neshika Samarasekera, Catharina JM Klijn, Floris HBM Schreuder
Publikováno v:
European Stroke Journal, 8, 2, pp. 423-433
European Stroke Journal, 8, 423-433
Cliteur, M P, Sondag, L, Cunningham, L, Al-Shahi Salman, R, Samarasekera, N, Klijn, C J & Schreuder, F H 2023, ' The association between perihaematomal oedema and functional outcome after spontaneous intracerebral haemorrhage: A systematic review and meta-analysis ', European Stroke Journal . https://doi.org/10.1177/23969873231157884
European Stroke Journal, 8, 423-433
Cliteur, M P, Sondag, L, Cunningham, L, Al-Shahi Salman, R, Samarasekera, N, Klijn, C J & Schreuder, F H 2023, ' The association between perihaematomal oedema and functional outcome after spontaneous intracerebral haemorrhage: A systematic review and meta-analysis ', European Stroke Journal . https://doi.org/10.1177/23969873231157884
Purpose: Perihaematomal oedema (PHO) formation has gained increasing interest as a therapeutic target after spontaneous intracerebral haemorrhage (ICH). Whether PHO contributes to poor outcome is unclear. We aimed to determine the association between
Autor:
Neshika Samarasekera, Michael Tc Poon, Rustam Al-Shahi Salman, Catharina J.M. Klijn, Owen Dando, Caoimhe Kirby, Barry W. McColl, Floris H.B.M. Schreuder, James J M Loan, Giles E. Hardingham, Katherine Emelianova, Leisan Pimenova
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
Loan, J J, Kirby, C, Emelianova, K, Dando, O R, Poon, M T, Pimenova, L, Hardingham, G E, Mccoll, B W, Klijn, C J, Al-shahi Salman, R, Schreuder, F H & Samarasekera, N 2021, ' Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue ', Journal of Neurology, Neurosurgery & Psychiatry, pp. jnnp-2021-327098 . https://doi.org/10.1136/jnnp-2021-327098
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 2, pp. 126-132
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 126-132
Loan, J J, Kirby, C, Emelianova, K, Dando, O R, Poon, M T, Pimenova, L, Hardingham, G E, Mccoll, B W, Klijn, C J, Al-shahi Salman, R, Schreuder, F H & Samarasekera, N 2021, ' Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue ', Journal of Neurology, Neurosurgery & Psychiatry, pp. jnnp-2021-327098 . https://doi.org/10.1136/jnnp-2021-327098
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 2, pp. 126-132
Journal of Neurology, Neurosurgery, and Psychiatry, 93, 126-132
BackgroundInflammatory responses to intracerebral haemorrhage (ICH) are potential therapeutic targets. We aimed to quantify molecular markers of inflammation in human brain tissue after ICH compared with controls using meta-analysis.MethodsWe searche