The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits

Autor: Nadia Rosenberg, Jean-Yves Chatton, Céline Schmuziger, Haissa de Castro Abrantes, Julien Puyal, Leonardo Restivo, Stefan Offermanns, Anne-Bérengère Rocher, Marc Briquet

Publikováno v: The Journal of neuroscience, vol. 39, no. 23, pp. 4422-4433

The discovery of a G-protein-coupled receptor for lactate named hydroxycarboxylic acid receptor 1 (HCAR1) in neurons has pointed to additional nonmetabolic effects of lactate for regulating neuronal network activity. In this study, we characterized t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1ddc0faab920f78a8b98536bd98952
https://serval.unil.ch/resource/serval:BIB_A7DD5C903273.P001/REF.pdf

Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity

Autor: Barbara Duff, Andrew M. McIntosh, Nicholas J. Brandon, Neil Roberts, Stephen Giles, Emma Sprooten, Bill Moorhead, Zoë A. Hughes, Jeremy Hall, Pippa A. Thomson, Liana Romaniuk, Scott Semple, Rali Dimitrova, Maria R. Dauvermann, Andrew Watson, Heather C. Whalley, Stephen M. Lawrie, Mark E. Bastin, Brandon Whitcher, John Dunlop, Douglas Blackwood

Publikováno v: Whalley, H C, Dimitrova, R, Sprooten, E, Dauvermann, MR, Romaniuk, L, Duff, B, Watson, A, Moorhead, B, Bastin, M E, Semple, S, Giles, S, Hall, J, Thomson, P, Roberts, N, Hughes, Z, Brandon, N, Dunlop, J, Whitcher, B, Blackwood, D, McIntosh, A M & Lawrie, S M 2015, ' Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity ', PLoS ONE, vol. 10, no. 6, e0130900 . https://doi.org/10.1371/journal.pone.0130900
PLoS ONE
Whalley, H, Dimitrova, R, Sprooten, E, Dauvermann, M R, Romaniuk, L, Duff, B, Watson, A, Moorhead, B, Bastin, M, Semple, S I, Giles, S, Hall, J, Thomson, P, Roberts, N, Hughes, Z, J Brandon, N, Dunlop, J, Whitcher, B, Blackwood, D, McIntosh, A & Lawrie, S 2015, ' Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity ', PLoS ONE . https://doi.org/10.1371/journal.pone.0130900
PLoS ONE, Vol 10, Iss 6, p e0130900 (2015)

Objective\ud \ud Individuals carrying rare, but biologically informative genetic variants provide a unique opportunity to model major mental illness and inform understanding of disease mechanisms. The rarity of such variations means that their study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3234b3519138816c9a70701fe4eacde5
https://kclpure.kcl.ac.uk/ws/files/44357943/pone.0130900.pdf

Delayed priming promotes CNS regeneration post-rhizotomy in Neurocan and Brevican-deficient mice

Autor: X. Quaglia, A. D. Zurn, C. Seidenbecher, A. T. Beggah

Publikováno v: Brain, vol. 131, no. Pt 1, pp. 240-249

A wealth of literature has provided evidence that reactive tissue at the site of CNS injury is rich in chondroitin sulfate proteoglycans which may contribute to the non-permissive nature of the CNS. We have recently demonstrated using a murine model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175f4f09c576976e1de4e3913072dbba
https://serval.unil.ch/notice/serval:BIB_BC504ABF378E

Globular Adiponectin, Acting via AdipoR1/APPL1, Protects H9c2 Cells from Hypoxia/Reoxygenation-Induced Apoptosis

Autor: Xi-Long Zheng, Min Park, Byung-Soo Youn, Aimin Xu, Donghai Wu, Gary Sweeney

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 4, p e19143 (2011)

Cardiomyocyte apoptosis is an important remodeling event contributing to heart failure and adiponectin may mediate cardioprotective effects at least in part via attenuating apoptosis. Here we used hypoxia-reoxygenation (H/R) induced apoptosis in H9c2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43df80aaba9fd1458a3b6fd9235a8155
https://doi.org/10.1371/journal.pone.0019143