Correction: A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing

Autor: Sören Frahm, Anisuzzaman Anisuzzaman, Ulrich Fabien Prodjinotho, Nermina Vejzagić, Admar Verschoor, Clarissa Prazeres da Costa

Publikováno v: PLoS Neglected Tropical Diseases, Vol 16, Iss 6 (2022)

Externí odkaz: https://doaj.org/article/2bed9489c8784e298b4cafa9155a0b66

A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing.

Autor: Sören Frahm, Anisuzzaman Anisuzzaman, Ulrich Fabien Prodjinotho, Nermina Vejzagić, Admar Verschoor, Clarissa Prazeres da Costa

Publikováno v: PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0006590 (2019)

BACKGROUND:The arsenal in anthelminthic treatment against schistosomiasis is limited and relies almost exclusively on a single drug, praziquantel (PZQ). Thus, resistance to PZQ could constitute a major threat. Even though PZQ is potent in killing adu

Externí odkaz: https://doaj.org/article/ba53240f691c4e0e907b5317c755eea5

Temperature dependent embryonic development of Trichuris suis eggs in a medicinal raw material

Autor: Allan Roepstorff, Anette Blak Grossi, Nermina Vejzagić, Johan Musaeus Bruun, Stig Milan Thamsborg, Helene Kringel, Christian M. O. Kapel

Publikováno v: Veterinary Parasitology. 215:48-57

The therapeutic potential of infective pig whipworm eggs, Trichuris suis ova (TSO), is currently tested in several clinical trials on immune-mediated diseases. This paper studied the embryonic development of TSO in a medicinal raw product, where the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6f6f6ce7ecaf63b85753a0d94881b2
https://doi.org/10.1016/j.vetpar.2015.10.031

Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis

Autor: Roberto Adelfio, Helene Kringel, Christian M. O. Kapel, Nermina Vejzagić, Jennifer Keiser, Stig Milan Thamsborg

Publikováno v: Vejzagic, N, Adelfio, R, Keiser, J, Kringel, H, Thamsborg, S M & Kapel, C M O 2015, ' Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis ', Parasites & Vectors, vol. 8, 371 . https://doi.org/10.1186/s13071-015-0986-z
Parasites & Vectors

BACKGROUND: Eggs of the porcine whipworm Trichuris suis are currently explored in human clinical trials as a treatment of immune-mediated diseases. In this context, only the infective, embryonated eggs, constitute the Active Pharmaceutical Ingredient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb478251b18a6895f367c9421b32652
https://doi.org/10.1186/s13071-015-0986-z

OvaSpec - A vision-based instrument for assessing concentration and developmental stage of Trichuris suis parasite egg suspensions

Autor: Svend Christensen, Nermina Vejzagić, Christian M. O. Kapel, Allan Roepstorff, Johan Musaeus Bruun, Jens Michael Carstensen

Publikováno v: Computers in biology and medicine. 53

BackgroundOvaSpec is a new, fully automated, vision-based instrument for assessing the quantity (concentration) and quality (embryonation percentage) of Trichuris suis parasite eggs in liquid suspension. The eggs constitute the active pharmaceutical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb49e36057f29f0d67eb2ac14fe531f
https://pubmed.ncbi.nlm.nih.gov/25129021