Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nermeen, Fawzy"'
Autor:
Dominik Bulfon, Johannes Breithofer, Gernot F. Grabner, Nermeen Fawzy, Anita Pirchheim, Heimo Wolinski, Dagmar Kolb, Lennart Hartig, Martin Tischitz, Clara Zitta, Greta Bramerdorfer, Achim Lass, Ulrike Taschler, Dagmar Kratky, Peter Greimel, Robert Zimmermann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Bis(monoacylglycero)phosphate (BMP) is a major phospholipid constituent of intralumenal membranes in late endosomes/lysosomes, where it regulates the degradation and sorting of lipid cargo. Recent observations suggest that the Batten disease
Externí odkaz:
https://doaj.org/article/29ec4e2adaf241899bdcc3d74c8b6fe0
Autor:
Natascha Berger, Tom van der Wel, Birgit Hirschmugl, Thomas Baernthaler, Juergen Gindlhuber, Nermeen Fawzy, Thomas Eichmann, Ruth Birner-Gruenberger, Robert Zimmermann, Mario van der Stelt, Christian Wadsack
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionLipids and fatty acids are key components in metabolic processes of the human placenta, thereby contributing to the development of the fetus. Placental dyslipidemia and aberrant activity of lipases have been linked to diverse pregnancy as
Externí odkaz:
https://doaj.org/article/554df234a0eb4e46ba913fb591099917
Autor:
Gernot F. Grabner, Nermeen Fawzy, Renate Schreiber, Lisa M. Pusch, Dominik Bulfon, Harald Koefeler, Thomas O. Eichmann, Achim Lass, Martina Schweiger, Gunther Marsche, Gabriele Schoiswohl, Ulrike Taschler, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 995-1003 (2020)
Bis(monoacylglycero)phosphate (BMP), also known as lysobisphosphatidic acid, is a phospholipid that promotes lipid sorting in late endosomes/lysosomes by activating lipid hydrolases and lipid transfer proteins. Changes in the cellular BMP content the
Externí odkaz:
https://doaj.org/article/2be18605ca1f457e8139b8198ab5f48a
Autor:
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 1020-1031 (2019)
Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and
Externí odkaz:
https://doaj.org/article/6811fbb03319497cbbdc699b457cff47
Autor:
Gernot F. Grabner, Nikolaus Guttenberger, Nicole Mayer, Anna K. Migglautsch-Sulzer, Christian Lembacher-Fadum, Nermeen Fawzy, Dominik Bulfon, Peter Hofer, Thomas Züllig, Lennart Hartig, Natalia Kulminskaya, Gabriel Chalhoub, Margarita Schratter, Franz P. W. Radner, Karina Preiss-Landl, Sarah Masser, Achim Lass, Rudolf Zechner, Karl Gruber, Monika Oberer, Rolf Breinbauer, Robert Zimmermann
Publikováno v:
Journal of the American Chemical Society. 144(14)
Chronically elevated circulating fatty acid levels promote lipid accumulation in nonadipose tissues and cause lipotoxicity. Adipose triglyceride lipase (ATGL) critically determines the release of fatty acids from white adipose tissue, and accumulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9667abe7b8e208351783e5895f0ec5e7
https://pubmed.ncbi.nlm.nih.gov/35362954
https://pubmed.ncbi.nlm.nih.gov/35362954
Autor:
Renate Schreiber, Dominik Bulfon, Lisa M. Pusch, Gabriele Schoiswohl, Gunther Marsche, Gernot F. Grabner, Ulrike Taschler, Martina Schweiger, Achim Lass, Robert Zimmermann, Harald Koefeler, Nermeen Fawzy, Thomas O. Eichmann
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 995-1003 (2020)
Journal of Lipid Research
Journal of Lipid Research
Bis(monoacylglycero)phosphate (BMP), also known as lysobisphosphatidic acid, is a phospholipid that promotes lipid sorting in late endosomes/lysosomes by activating lipid hydrolases and lipid transfer proteins. Changes in the cellular BMP content the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b4e1ee9b0eafecf4c3f5b5055ec03c
https://doi.org/10.1194/jlr.ra119000516
https://doi.org/10.1194/jlr.ra119000516
Autor:
Laura, Pajed, Carina, Wagner, Ulrike, Taschler, Renate, Schreiber, Stephanie, Kolleritsch, Nermeen, Fawzy, Isabella, Pototschnig, Gabriele, Schoiswohl, Lisa-Maria, Pusch, Beatrix I, Wieser, Paul, Vesely, Gerald, Hoefler, Thomas O, Eichmann, Robert, Zimmermann, Achim, Lass
Publikováno v:
The Journal of Biological Chemistry
Lysosomal acid lipase (LAL) hydrolyzes cholesteryl ester (CE) and retinyl ester (RE) and triglyceride (TG). Mice globally lacking LAL accumulate CE most prominently in the liver. The severity of the CE accumulation phenotype progresses with age and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d316a73aa697d182aeb83ffefffbed5
https://pubmed.ncbi.nlm.nih.gov/31023823
https://pubmed.ncbi.nlm.nih.gov/31023823
Autor:
Magdalena Grill, Christian Wadsack, Birgit Hirschmugl, Nermeen Fawzy, Robert Zimmermann, Rudolf Schicho, Uwe Lang
Publikováno v:
Placenta. 83:e60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82272f1fe672b636db832759350f806
https://doi.org/10.1016/j.placenta.2019.06.197
https://doi.org/10.1016/j.placenta.2019.06.197
Publikováno v:
Food and Chemical Toxicology. 49:903-909
A standardized extract of the fruits of Solanum distichum has previously been shown to possess anti-hypertensive activity in rats (ED50 about 1 mg/kg). Earlier acute toxicity studies had shown that single doses up to 2g/kg orally or intraperitoneally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d85c38ea29364895f38ac8d57d39cb7
https://doi.org/10.1016/j.fct.2010.11.048
https://doi.org/10.1016/j.fct.2010.11.048
