Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nerea Llamosas"'
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 944-954 (2015)
Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson’s disease (PD) and psychiatric disorders. L-DOPA, the leading treatment of PD, facilitates the production and release o
Externí odkaz:
https://doaj.org/article/9b8633881a464208b3292526d35a81d2
Autor:
Adrian Reich, Courtney A. Miller, Vineet Arora, Gavin Rumbaugh, BanuPriya Sridharan, Murat Kilinc, J. Lloyd Holder, Lukasz Bijoch, Nerea Llamosas, David R. Piper, Louis Scampavia, Camilo Rojas, Timothy P. Spicer, Erik Willems, Ridhima Vij
Publikováno v:
J Neurosci
SYNGAP1is a major genetic risk factor for global developmental delay, autism spectrum disorder, and epileptic encephalopathy.De novoloss-of-function variants in this gene cause a neurodevelopmental disorder defined by cognitive impairment, social-com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf22e6ca5215ce4ed1bf45542dad19c
https://doi.org/10.1523/jneurosci.1367-20.2020
https://doi.org/10.1523/jneurosci.1367-20.2020
Autor:
Courtney A. Miller, Gavin Rumbaugh, Nerea Llamosas, Camilo Rojas, Sheldon D Michaelson, Thomas Vaissière
Publikováno v:
Proc Natl Acad Sci U S A
A significant proportion of autism risk genes regulate synapse function, including plasticity, which is believed to contribute to behavioral abnormalities. However, it remains unclear how impaired synapse plasticity contributes to network-level proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960291a91efe5c5ef17559f1e5fbc0e3
https://europepmc.org/articles/PMC8403968/
https://europepmc.org/articles/PMC8403968/
Autor:
Luisa Ugedo, Nerea Llamosas, Laura Perez-Caballero, Esther Berrocoso, María Torrecilla, Cristina Bruzos-Cidón
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 88:243-252
Accumulating evidence indicates that the antidepressant effects of ketamine are, in part, mediated by an increase in the AMPA receptor-mediated neurotransmission in depression related areas, such as the prefrontal cortex (PFC). Therefore, activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fcdcc55e82684cb659835f7a9b9961
https://doi.org/10.1016/j.pnpbp.2018.07.022
https://doi.org/10.1016/j.pnpbp.2018.07.022
Autor:
Rojas C, Lukasz Bijoch, Gavin Rumbaugh, Timothy P. Spicer, Louis Scampavia, Jimmy Holder, David R. Piper, Adrian Reich, Vij R, Nerea Llamosas, Erik Willems, Murat Kilinc, Courtney A. Miller, Arora, BanuPriya Sridharan
SYNGAP1 is a major genetic risk factor for global developmental delay, autism spectrum disorder, and epileptic encephalopathy. De novo loss-of-function variants in this gene cause a neurodevelopmental disorder defined by cognitive impairment, social-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d54cafea3d01ed0cf5ddf15864148201
https://doi.org/10.1101/2020.06.01.127613
https://doi.org/10.1101/2020.06.01.127613
Autor:
Gavin Rumbaugh, Thomas Vaissière, Camilo Rojas, Nerea Llamosas, Courtney A. Miller, Sheldon D Michaelson
Experience induces complex, neuron-specific changes in population activity within sensory cortex circuits. However, the mechanisms that enable neuron-specific changes within cortical populations remain unclear. To explore the idea that synapse streng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0c4f0d9cec70b63bacd9235b4c032b
Autor:
Murat Kilinc, Christopher Hubbs, Gavin Rumbaugh, Nerea Llamosas, Erik Willems, Timothy P. Spicer, Fakhar Singhera, Louis Scampavia, David R. Piper, BanuPriya Sridharan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Neurons created from human induced pluripotent stem cells (hiPSCs) provide the capability of identifying biological mechanisms that underlie brain disorders. IPSC-derived human neurons, or iNs, hold promise for advancing precision medicine through dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36ae38b67950fe679e77a00df311df3
https://doi.org/10.1038/s41598-019-45265-1
https://doi.org/10.1038/s41598-019-45265-1
Autor:
Luisa Ugedo, Przemysław Eligiusz Cieślak, María Torrecilla, Kamila Jastrzębska, Tomasz Kos, Nerea Llamosas, J Rodriguez Parkitna
Publikováno v:
Genes, Brain and Behavior.
Activity of the brain's noradrenergic (NA) neurons plays a major role in cognitive processes, including the ability to adapt behavior to changing environmental circumstances. Here, we used the NR1DbhCre transgenic mouse strain to test how NMDA recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ec251a6c963d3a654f7364a82cd4aca
https://doi.org/10.1111/gbb.12383
https://doi.org/10.1111/gbb.12383
Publikováno v:
Physiological Reports
The serotonergic tone of the dorsal raphe (DR) is regulated by 5‐HT 1A receptors, which negatively control serotonergic activity via the activation of G protein‐coupled inwardly rectifying K+ (GIRK) channels. In addition, DR activity is modulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a15a6330a4b29d2010b40d802286715
https://pubmed.ncbi.nlm.nih.gov/28196855
https://pubmed.ncbi.nlm.nih.gov/28196855
Publikováno v:
International Journal of Neuropsychopharmacology
Background: The noradrenergic nucleus locus coeruleus (LC) has functional relevance in several psychopathologies such as stress, anxiety, and depression. In addition to glutamatergic and GABAergic synaptic inputs, the activation of somatodendritic α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8801e4607011531ebea89242cce86c
https://pubmed.ncbi.nlm.nih.gov/25586927
https://pubmed.ncbi.nlm.nih.gov/25586927