The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron

Autor: Alain Doucet, Marc Maillard, Caroline Ronzaud, Lydie Cheval, Alessia Spirli, David Penton, Olivier Staub, Anne Debonneville, Johannes Loffing

Publikováno v: Physiological Reports
Physiological Reports, Wiley, 2019, 7 (15), pp.e14177. ⟨10.14814/phy2.14177⟩
Physiological Reports, Vol 7, Iss 15, Pp n/a-n/a (2019)
Physiological reports, vol. 7, no. 15, pp. e14177

The mineralocorticoid hormone aldosterone plays a crucial role in the control of Na + and K + balance, blood volume, and arterial blood pressure, by acting in the aldosterone-sensitive distal nephron (ASDN) and stimulating a complex transcriptional,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bbbeddbf0e4b0f31cde39f7e0ea947
https://doi.org/10.14814/phy2.14177

CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia

Autor: Dorothee Günzel, Huguette Debaix, Iwan C. Meij, Thomas E. Willnow, Julia Thumfart, Uwe Querfeld, Vladimír Němec, Nine V A M Knoers, Joost G. J. Hoenderop, Kerstin Sommer, Dominik N. Müller, Constanze Will, Nicole B. Kampik, Carsten A. Wagner, Olivier Devuyst, Sergio Lainez, René J. M. Bindels, Marchel Stuiver, Kathrin Kopplin, Sara Terryn

Publikováno v: American Journal of Human Genetics, 88, 3, pp. 333-43
The American Journal of Human Genetics
The American Journal of Human Genetics; Vol 88
American Journal of Human Genetics, 88(3), 333-343. CELL PRESS
American Journal of Human Genetics, 88, 333-43

Item does not contain fulltext Familial hypomagnesemia is a rare human disorder caused by renal or intestinal magnesium (Mg(2+)) wasting, which may lead to symptoms of Mg(2+) depletion such as tetany, seizures, and cardiac arrhythmias. Our knowledge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84a2c1f46bb0e13ad7dd1a7a524e4a0
https://hdl.handle.net/2066/96685