Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nephrology/Tubulointerstitial Diseases"'
Autor:
Hjalti Gudmundsson, Thorvaldur Magnússon, Margrét Árnadóttir, Margrét B. Andrésdóttir, Sverrir Hardarson, Vala Kolbrún Pálmadóttir
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13484 (2010)
PLoS ONE
PLoS ONE
Background Oral sodium phosphate solutions (OSPS) are widely used for bowel cleansing prior to colonoscopy and other procedures. Cases of renal failure due to acute phosphate nephropathy following OSPS ingestion have been documented in recent years,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7832e6e085cc667607b2df35743eb342
http://europepmc.org/articles/PMC2957439?pdf=render
http://europepmc.org/articles/PMC2957439?pdf=render
Autor:
Linda C Enns, John F Morton, Piper R Treuting, Mary J Emond, Norman S Wolf, Dao-Fu Dai, G S McKnight, Peter S Rabinovitch, Warren C Ladiges
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 6, p e5963 (2009)
PLoS ONE, Vol 4, Iss 6, p e5963 (2009)
Mutations that cause a reduction in protein kinase A (PKA) activity have been shown to extend lifespan in yeast. Loss of function of mammalian RIIbeta, a regulatory subunit of PKA expressed in brain and adipose tissue, results in mice that are lean a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b684dcff7786b41698aa21553f4e8624
http://europepmc.org/articles/PMC2693670
http://europepmc.org/articles/PMC2693670
Autor:
Edgar A. Otto, Eric Wise, Peter Nürnberg, Christopher N. Vlangos, Friedhelm Hildebrandt, Virginia Vega-Warner, Shazia Ashraf, Christian Becker, Bethan E. Hoskins, Gudrun Nürnberg, Gil Chernin, Bernward Hinkes, Hassan Chaib, John F. O'Toole, Weibin Zhou, Saskia F. Heeringa, Norbert Huebner, Franz Rüschendorf, James W. MacDonald, Dominik S. Schoeb, Robert H. Lyons, Joseph Washburn, Dominik Seelow, Bugsu Ovunc, Massimo Attanasio, Susan J. Allen, Heather M. Harville, Matthias T.F. Wolf
Publikováno v:
PLoS Genetics, Vol 5, Iss 1, p e1000353 (2009)
PLoS Genetics
PLoS Genetics
The identification of recessive disease-causing genes by homozygosity mapping is often restricted by lack of suitable consanguineous families. To overcome these limitations, we apply homozygosity mapping to single affected individuals from outbred po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39af2bd21e607b8c7da348dd99dcffb1
http://europepmc.org/articles/PMC2621355?pdf=render
http://europepmc.org/articles/PMC2621355?pdf=render
Autor:
Gwendoline J. D. Teske, Jaklien C. Leemans, Wilco P. Pulskens, Loes M. Butter, Sandrine Florquin, Tom van der Poll, Nike Claessen
Publikováno v:
PLoS ONE
PLoS ONE, 4(5). Public Library of Science
PLoS ONE, Vol 4, Iss 5, p e5704 (2009)
PLoS ONE, 4(5). Public Library of Science
PLoS ONE, Vol 4, Iss 5, p e5704 (2009)
Tissue fibrosis and chronic inflammation are common causes of progressive organ damage, including progressive renal disease, leading to loss of physiological functions. Recently, it was shown that Toll-like receptor 2 (TLR2) is expressed in the kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a7c0ccbeb76aaad4c35191f824c2e2
https://pubmed.ncbi.nlm.nih.gov/19479087
https://pubmed.ncbi.nlm.nih.gov/19479087
Autor:
Thomas R. Welch, Lisa W. Blystone
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 10, p e3334 (2008)
PLoS ONE, Vol 3, Iss 10, p e3334 (2008)
Background The role of circulating complement in host defense and immune disease is well established. Although a number of cells and tissues are capable of synthesizing complement components locally, the importance of such local synthesis in immune d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3b384c6373613a1800aea0c638afd8
http://europepmc.org/articles/PMC2553262
http://europepmc.org/articles/PMC2553262
Autor:
Volker H. Haase, Marc Yudkoff, Marni J. Falk, Mary A. Selak, Erzsebet Polyak, Min Peng, Ray Meade, Wayne W. Hancock, David L. Gasser, Catherine F. Clarke, Rhonda King, Adam L. Lunceford, Ryoichi Saiki
Publikováno v:
PLoS genetics, vol 4, iss 4
PLoS Genetics
PLoS Genetics, Vol 4, Iss 4, p e1000061 (2008)
PLoS Genetics
PLoS Genetics, Vol 4, Iss 4, p e1000061 (2008)
Coenzyme Q (CoQ) is an essential electron carrier in the respiratory chain whose deficiency has been implicated in a wide variety of human mitochondrial disease manifestations. Its multi-step biosynthesis involves production of polyisoprenoid diphosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb182c03fabe1e3087f857a3248a6a5
https://escholarship.org/uc/item/2g96r43r
https://escholarship.org/uc/item/2g96r43r
Autor:
Maria Heloisa Massola Shimizu, Reinaldo Correia Silva, Georgia Daniela Marcusso Marques, Antonio Carlos Seguro, Ana Paula Fernandes da Silva Monteiro, Giselle Martins Gonçalves, Ana Carolina Guimarães Faleiros, Niels Olsen Saraiva Câmara, Alexandre C. Keller, Patricia Semedo, Marcos Antonio Cenedeze, Marlene Antônia dos Reis, Rafael Pereira, Matheus Correa-Costa, Alvaro Pacheco-Silva
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14298 (2010)
PLoS ONE
PLoS ONE
Background: The tubule-interstitial fibrosis is the hallmark of progressive renal disease and is strongly associated with inflammation of this compartment. Heme-oxygenase-1 (HO-1) is a cytoprotective molecule that has been shown to be beneficial in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc8debc2a85b7e66035e822b8d9b6d8
https://doi.org/10.1371/journal.pone.0014298
https://doi.org/10.1371/journal.pone.0014298
Autor:
Shigeyoshi Oba, Kenjiro Kimura, Hiroaki Nishimatsu, Etsu Suzuki, Masatoshi Kasuya, Yousuke Ogawa, Hajime Takamori, Toshiro Fujita, Yasunobu Hirata, Masao Takahashi, Shintaro Kumano, Kenichiro Sato, Yukio Homma
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13614 (2010)
PLoS ONE
PLoS ONE
Members of the miR-200 family of micro RNAs (miRNAs) have been shown to inhibit epithelial-mesenchymal transition (EMT). EMT of tubular epithelial cells is the mechanism by which renal fibroblasts are generated. Here we show that miR-200 family membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e81e69880635ecacae5ea9bd8522e5
https://doi.org/10.1371/journal.pone.0013614
https://doi.org/10.1371/journal.pone.0013614
Autor:
Hubert Kalbacher, Markus A. Kuczyk, Claudia A. Müller, Cornelia Thedieck, Gerhard A. Müller, Gerd Klein
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e657 (2007)
PLoS ONE
PLoS ONE
BackgroundInterstitial fibroblasts are a minor, but nevertheless very important, component of the kidney. They secrete and remodel extracellular matrix and they produce active compounds such as erythropoietin. However, studying human renal fibroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b94ce79edb6a28f511428a540c42c3
https://doi.org/10.1371/journal.pone.0000657
https://doi.org/10.1371/journal.pone.0000657