Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Neonila Beregovskaya"'
Autor:
Neonila Beregovskaya, Yuri Beregovski
Publikováno v:
Journal of Theoretical Biology. 189:81-88
A simple model of DNA damage (mutation load) accumulation is considered. For time intervals exceeding average life duration, the kinetics of mutation load is determined. The major process determining these kinetics is shown to be natural selection (o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b5b71ae4a4adb89b7d48ab0dfbdebd
https://doi.org/10.1006/jtbi.1997.0500
https://doi.org/10.1006/jtbi.1997.0500
Publikováno v:
Journal of theoretical biology. 172(2)
The role of mitochondrial DNA (mtDNA) damage in ageing processes and in malignant transformation of a cell is discussed. A mathematical model of the mtDNA population in a cell and in tissue is constructed. The model describes the effects of mtDNA dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc45e4683486f98b60dfc55ce6995735
https://pubmed.ncbi.nlm.nih.gov/7891454
https://pubmed.ncbi.nlm.nih.gov/7891454