Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Neonatal Fc Receptor (FcRn)"'
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Recent development of amyloid-β (Aβ)-targeted immunotherapies for Alzheimer’s disease (AD) have highlighted the need for accurate diagnostic methods. Antibody-based positron emission tomography (PET) ligands are well suited for this purpose as th
Externí odkaz:
https://doaj.org/article/e26e8d4cee664eda81a36e31dae1d509
Autor:
Felix Stader, Cong Liu, Abdallah Derbalah, Hiroshi Momiji, Xian Pan, Iain Gardner, Masoud Jamei, Armin Sepp
Publikováno v:
Antibodies, Vol 13, Iss 3, p 70 (2024)
The bioavailability of a monoclonal antibody (mAb) or another therapeutic protein after subcutaneous (SC) dosing is challenging to predict from first principles, even if the impact of injection site physiology and drug properties on mAb bioavailabili
Externí odkaz:
https://doaj.org/article/0318d20ff39a45c19a6b62c7a4b24ef2
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
IntroductionThyroid eye disease (TED) is an immune-mediated disorder associated with a heterogenous array of manifestations that may unfavorably impact vision and quality of life. As understanding of this entity’s complex pathogenesis has evolved,
Externí odkaz:
https://doaj.org/article/5b214bd6e6a34837948c4668c05ad895
Autor:
Jason Tien, Dmitri Leonoudakis, Ralitsa Petrova, Vivian Trinh, Tetsuya Taura, Debapriya Sengupta, Lisa Jo, Angela Sho, Yong Yun, Eric Doan, Anita Jamin, Hussein Hallak, David S. Wilson, Jennifer R. Stratton
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe blood-brain barrier (BBB) largely excludes antibodies from entering the central nervous system, thus limiting the potential of therapeutic antibodies to treat conditions such as neurodegenerative diseases and neuro-psychiatric disorders.
Externí odkaz:
https://doaj.org/article/cdaf2256be904993bfc4da5093e8c198
Autor:
Vinaya Bhandari, Vera Bril
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Myasthenia gravis (MG) is an autoimmune disorder characterized by autoantibodies specifically directed against proteins located within the postsynaptic membrane of the neuromuscular junction. These pathogenic autoantibodies can be reduced by therapie
Externí odkaz:
https://doaj.org/article/39d941d860e942a5aab48ba46f2534b4
Autor:
Hanine Rafidi, Sharmila Rajan, Konnie Urban, Whitney Shatz-Binder, Keliana Hui, Gregory Z. Ferl, Amrita V. Kamath, C. Andrew Boswell
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Advances in antibody engineering have enabled the construction of novel molecular formats in diverse shapes and sizes, providing new opportunities for biologic therapies and expanding the need to understand how various structural aspects affect their
Externí odkaz:
https://doaj.org/article/6c3322f467974ab2941978a377de89ce
Akademický článek
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Autor:
Chandra B. Prabaharan, Sabeena Giri, Kevin J. H. Allen, Katrina E. M. Bato, Therese R. Mercado, Mackenzie E. Malo, Jorge L. C. Carvalho, Ekaterina Dadachova, Maruti Uppalapati
Publikováno v:
Molecules, Vol 28, Iss 15, p 5839 (2023)
Novel therapeutic approaches are much needed for the treatment of osteosarcoma. Targeted radionuclide therapy (TRT) and radioimmunotherapy (RIT) are promising approaches that deliver therapeutic radiation precisely to the tumor site. We have previous
Externí odkaz:
https://doaj.org/article/48fe470b2a6848f39dc41d8d274e15e4
Autor:
Dario Didona, Giovanni Paolino, Giovanni Di Zenzo, Biagio Didona, Riccardo Pampena, Matteo Riccardo Di Nicola, Santo Raffaele Mercuri
Publikováno v:
Dermatology Practical & Conceptual (2022)
Pemphigus vulgaris (PV) belongs to the group of autoimmune blistering diseases. PV can affect not only mucous membranes, but also the skin and it is characterized by serum IgG autoantibodies against desmoglein 1 and 3, two major components of desmoso
Externí odkaz:
https://doaj.org/article/bb8ca9ffd5b44e4b8a93ef8a1d936027
Akademický článek
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