Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Neomycins"'
Autor:
Lauren Parkinson, Tamara M. Stawicki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0246844 (2021)
PLoS ONE, Vol 16, Iss 4, p e0246844 (2021)
Multiple cilia-associated genes have been shown to affect hair cells in zebrafish (Danio rerio), including the human deafness genedcdc2, the radial spoke genersph9, and multiple intraflagellar transport (IFT) and transition zone genes. Recently a zeb
Akademický článek
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Autor:
Luca Monti, Doron Shmerling, Stephan Sonntag, Anna Teti, Antonio Maurizi, Rossella Costantini, Antonio Rossi, Antonella Forlino, Chiara Paganini, Mattia Capulli
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0213660 (2019)
PLoS ONE, 14 (3)
PLoS ONE, Vol 14, Iss 3, p e0213660 (2019)
PLoS ONE, 14 (3)
The Cre-mediated genetic switch combines the ability of Cre recombinase to stably invert or excise a DNA fragment depending upon the orientation of flanking mutant loxP sites. In this work, we have tested this strategy in vivo with the aim to generat
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240480 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240480 (2020)
Global amphibian populations are being decimated by chytridiomycosis, a deadly skin infection caused by the fungal pathogens Batrachochytrium dendrobatidis (Bd) and B. salamandrivorans (Bsal). Although ongoing efforts are attempting to limit the spre
Autor:
Keith Poole, Michael Fruci
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205036 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205036 (2018)
Exposure of P. aeruginosa to the aminoglycoside (AG) paromomycin (PAR) induced expression of the PA3720-armR locus and the mexAB-oprM multidrug efflux operon that AmgR controls, although PAR induction of mexAB-oprM was independent of armR. Multiple A
Autor:
Yoji Murata, Takashi Matozaki, Naoya Hatano, Tasuku Konno, Yasuaki Kitamura, Shinya Imada, Jajar Setiawan, Yasuyuki Saito, Masakazu Shinohara, Jung Ha Park, Yutaro Usui, Takenori Kotani
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0156334 (2016)
PLoS ONE, Vol 11, Iss 5, p e0156334 (2016)
The life span of intestinal epithelial cells (IECs) is short (3-5 days), and its regulation is thought to be important for homeostasis of the intestinal epithelium. We have now investigated the role of commensal bacteria in regulation of IEC turnover
Autor:
Diana Ideses, Dan Y. Even, Shani Basch-Barzilay, Orit Shefi, Hila Shir-Shapira, Tamar Juven-Gershon, Adi Kedmi, Ravid Tikotzki
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148918 (2016)
PLoS ONE, Vol 11, Iss 2, p e0148918 (2016)
The core promoter, which is generally defined as the region to which RNA Polymerase II is recruited to initiate transcription, plays a pivotal role in the regulation of gene expression. The core promoter consists of different combinations of several
Autor:
Marco Petrillo, Shan Sun, Mingqian Huang, Nikolaus D. Obholzer, Huawei Li, Wenyan Li, Zheng-Yi Chen, Pu Dai, Douglas A. Cotanche, Sang Goo Lee, Yi Zhou, Sean G. Megason
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0157768 (2016)
PLoS ONE, Vol 11, Iss 6, p e0157768 (2016)
Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery. The mechanisms underlying the regeneration are poorly un
Autor:
Maoxue Tang, Qingqing Wang, Pengfei Gao, Shengwang Jiang, Jie Liu, Dezun Ma, Ke Jiang, Wentao Cui, Jian Hou, Chunbo Cai, Hegang Li, Lili Qian
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0150937 (2016)
PLoS ONE, Vol 11, Iss 3, p e0150937 (2016)
The neo (neomycin phosphotransferase) gene is widely used as a selection marker in the production of genetically engineered animals and plants. Recent attention has been focused on safety concerns regarding neo transgene expression. In this study, ne
Autor:
Jenny J. Sun, Russell S. Ray
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159474 (2016)
PLoS ONE
PLoS ONE
CRISPR/Cas9 mediated DNA double strand cutting is emerging as a powerful approach to increase rates of homologous recombination of large targeting vectors, but the optimization of parameters, equipment and expertise required remain barriers to succes