Zobrazeno 1 - 10
of 2 337
pro vyhledávání: '"Neogenesis"'
Autor:
Fanglin Niu, Wenxuan Liu, Yuanyuan Ren, Ye Tian, Wenzhen Shi, Man Li, Yujia Li, Yuyan Xiong, Lu Qian
Publikováno v:
Journal of Advanced Research, Vol 62, Iss , Pp 71-89 (2024)
Background: Diabetes Mellitus (DM), a chronic metabolic disease characterized by elevated blood glucose, is caused by various degrees of insulin resistance and dysfunctional insulin secretion, resulting in hyperglycemia. The loss and failure of funct
Externí odkaz:
https://doaj.org/article/24763a20252f4ad0b78b5708187e4a82
Autor:
Esmaeel Ghasemi Gojani, Sweta Rai, Farzaneh Norouzkhani, Salma Shujat, Bo Wang, Dongping Li, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7621-7667 (2024)
The β-cells within the pancreas play a pivotal role in insulin production and secretion, responding to fluctuations in blood glucose levels. However, factors like obesity, dietary habits, and prolonged insulin resistance can compromise β-cell funct
Externí odkaz:
https://doaj.org/article/e7c55875d9b1454db99f789a8dec282f
Autor:
Maria Petropavlovskaia, Beatrice Assouline-Thomas, Jessica Cuerquis, Jing Zhao, Shaun Violette-Deslauriers, Eni Nano, Nicoletta Eliopoulos, Lawrence Rosenberg
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35372- (2024)
Mesenchymal stem/stromal cells (MSCs) are emerging as a new therapy for diabetes. Here we investigate the properties of MSCs engineered to express Islet Neogenesis Associated Protein (INGAP) previously shown to reverse diabetes in animal models and e
Externí odkaz:
https://doaj.org/article/f41f8cdf79f647ae8031aed30ac59381
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1558-1571 (2023)
Abstract Pipeline formation between tumor cells and the tumor microenvironment (TME) is a key event leading to tumor progression. These pipelines include blood vessels, lymphatics, and membranous vessels (the former two can be collectively referred t
Externí odkaz:
https://doaj.org/article/8e55061eafb546959b81ba6cd56d8afc
Akademický článek
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Autor:
Camilla Hartmann Friis Hansen, Martin Haupt‐Jorgensen, Karsten Buschard, Bente Pakkenberg, Lukasz Krych, Axel Kornerup Hansen
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Background Early antibiotic treatment changes susceptibility to disease in rodent models for type 1 diabetes, but the impact that gestational antibiotics may have on pancreatic embryogenesis and β cell function later in life is still unknow
Externí odkaz:
https://doaj.org/article/863784c01dfa40cab2ace2c2a46937e8
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114140- (2023)
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed
Externí odkaz:
https://doaj.org/article/8961b8034bb7482e9b6ac2fb34969b53
Autor:
Anna Söderström, Sofie Vonlanthen, Kerstin Jönsson-Videsäter, Stephan Mielke, Hannes Lindahl, Johan Törlén, Michael Uhlin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLymphocyte neogenesis from primary lymphoid organs is essential for a successful reconstitution of immunity after allogeneic hematopoietic stem cell transplantation (HSCT). This single-center retrospective study aimed to evaluate T cell rec
Externí odkaz:
https://doaj.org/article/c842265642344d5387eff84a0a287a94
Akademický článek
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Autor:
Luciana Ribeiro Jarduli‐Maciel, Júlia Teixeira Cottas de Azevedo, Emmanuel Clave, Thalita Cristina de Mello Costa, Lucas Coelho Marlière Arruda, Isabelle Fournier, Patrícia Vianna Bonini Palma, Keli Cristina Lima, Juliana Bernardes Elias, Ana Beatriz PL Stracieri, Fabiano Pieroni, Renato Cunha, Luiz Guilherme Darrigo‐Júnior, Carlos Eduardo Settani Grecco, Dimas Tadeu Covas, Ana Cristina Silva‐Pinto, Gil Cunha De Santis, Belinda Pinto Simões, Maria Carolina Oliveira, Antoine Toubert, Kelen Cristina Ribeiro Malmegrim
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 4, Pp n/a-n/a (2022)
Abstract Objectives Allogeneic haematopoietic stem cell transplantation (allo‐HSCT) is the only currently available curative treatment for sickle cell disease (SCD). Here, we comprehensively evaluated the reconstitution of T‐ and B‐cell compart
Externí odkaz:
https://doaj.org/article/c781cf229ea44de68805e00caa2a983d