Výsledky vyhledávání - "Nenita S. Tan"

Immunomodulation of cellular cytotoxicity to herpes simplex virus infection in pregnancy by inhibition of eicosanoid metabolism

Autor: Bernard Gonik, P.K. Donovan, Bruce B. Feinberg, Nenita S. Tan, K.C. Loftin

Publikováno v: Journal of reproductive immunology. 23(2)

In an effort to evaluate the relationships among pregnancy, cellular cytotoxicity and herpes simplex virus (HSV) infection, we conducted a series of experiments investigating: (1) the maternal cellular cytotoxic response to HSV infection as compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267df3c9f4e6a6d254990146bf1b8bec
https://pubmed.ncbi.nlm.nih.gov/8510075

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Progesterone and estradiol suppress human mononuclear cell cytotoxicity

Autor: Scott W. Walsh, Nenita S. Tan, Peter C. Brath, Bernard Gonik, Bruce B. Feinberg

Publikováno v: Journal of reproductive immunology. 21(2)

Fetal trophoblast is generally resistant to lysis by cytotoxic cells. We hypothesized that progesterone and estrogens secreted by the trophoblast act at the choriodecidual interface where they are present in high concentrations to provide a local, pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970888cbc704e24f66964f0e38c00e0f
https://pubmed.ncbi.nlm.nih.gov/1548628

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Increased progesterone concentrations are necessary to suppress interleukin-2-activated human mononuclear cell cytotoxicity

Autor: Bruce B. Feinberg, Nenita S. Tan, Scott W. Walsh, Peter C. Brath, Bernard Gonik

Publikováno v: American journal of obstetrics and gynecology. 165(6 Pt 1)

Fetal trophoblast is generally resistant to lysis by cytotoxic cells. Trophoblast progesterone and estrogens may act at the choriodecidual interface, where they are present in high concentrations to provide a local, paracrine immunosuppressive effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a771ec67192e9345661805c098e5a75
https://pubmed.ncbi.nlm.nih.gov/1750486

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Immune modulation of natural killer cell cytotoxicity against herpes infected target cells in pregnancy

Autor: Jerry Crump, Nenita S. Tan, Karin C. Loftin, Bernard Gonik

Publikováno v: American journal of reproductive immunology (New York, N.Y. : 1989). 24(4)

Natural killer cell cytotoxicity (NKC) is a nonspecific, primary immunodefense system active against a variety of pathogens, including herpes simplex virus (HSV). Evidence suggests that during pregnancy, NKC is attenuated. The regulatory mechanisms f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7b9433a0cf1b97909f992cad292c1c
https://pubmed.ncbi.nlm.nih.gov/2085395

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