Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Neng Qiu"'
Publikováno v:
Polymers, Vol 15, Iss 6, p 1400 (2023)
Cyclodextrins (CDs) are one of the most extensively studied cyclic-oligosaccharides due to their low toxicity, good biodegradability and biocompatibility, facile chemical modification, and unique inclusion capacity. However, problems such as poor pha
Externí odkaz:
https://doaj.org/article/88d62c8d2f5741e6a8ab793af6a57f57
Autor:
Jiaolin Wen, Neng Qiu, Zejiang Zhu, Peng Bai, Mengshi Hu, Wenyan Qi, Yan Liu, Ailin Wei, Lijuan Chen
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1055-1066 (2021)
Given the maturation of small-interfering RNA (siRNA) techniques with nanotechnology, and because overexpression of human programmed death-ligand 1 (PD-L1) is crucial for T cell inactivation and immunosuppression of the tumor microenvironment, applic
Externí odkaz:
https://doaj.org/article/c152ffbe18044135a9ff3b00f8c066e9
Autor:
Jiaolin Wen, Xianhuo Wang, Heying Pei, Caifeng Xie, Neng Qiu, Shucai Li, Wenwen Wang, Xia Cheng, Lijuan Chen
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 3, Pp 116-124 (2015)
Honokiol (HK), a biphenolic neolignan isolated from Magnolia officinalis, has been reported to possess anti-inflammatory and anti-angiogenic activaties. In this study, our aim was to investigate anti-psoriatic activities of HK and the involved mechan
Externí odkaz:
https://doaj.org/article/1a0ff7bf0dcf43ae93eb615fad59ac9c
Autor:
Li-Juan Chen, Ai-Hua Peng, Jing-Xiang Qiu, Fei Peng, Guang-Cheng Wang, Jin-Ying Chen, Neng Qiu, Liang Ma, Shi-Chao He, Qin-Yuan Xu, Rong-Hong Zhang, Tao Chen
Publikováno v:
Molecules, Vol 17, Iss 6, Pp 6249-6268 (2012)
Gambogic acid (GA) is in a phase II clinical trial as an antitumor and antiangiogenesis agent. In this study, 36 GA derivatives were synthesized and screened in a zebrafish model to evaluate their antiangiogenic activity and toxicity. Derivatives 4,
Externí odkaz:
https://doaj.org/article/fd163b9f84554322941558af5bb7dd29
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 7, Pp o1706-o1706 (2009)
The title compound, C13H12ClNO4, is approximately planar, with a dihedral angle of 8.23 (4)° between the mean plane of the aminomethylene unit and the planar part of the dioxane ring. The dioxane ring has a half-boat conformation, in which the C ato
Externí odkaz:
https://doaj.org/article/b91cb10b62d34157a2dff5dd6995a011
Autor:
Ying Jin, Xiangjie Di, Lisha Fu, Mengyu Zhang, Neng Qiu, Runhan Liu, Fangqun Li, Xiaohui Qi, Xiaoxu Wang, Yongsheng Wang, Zhenlei Wang
Publikováno v:
Bioanalysis. 14:1165-1175
Background: JRF103, a novel pan-HER inhibitor, has shown potent activity against HER1, HER2, HER4 and EGFR in vitro. To support its first in-patient trial, a sensitive and rapid method was developed and validated using ultra-performance LC–MS/MS. M
Autor:
Yingyu Ma, Lei Chen, Lian Deng, Xuebing Li, Xiu Zhao, Daobing Jiang, Jiabao Liu, Yang Song, Junda Liu, Nan Cui, Neng Qiu
Publikováno v:
Biomedical Materials.
Podophyllotoxin (PPT) is an active natural pharmaceutical component with potent anticancer activity. However, due to its poor water solubility and serious side effects, its medical applications are limited. In this work, we synthesized a series of PP
Autor:
Zejiang Zhu, Neng Qiu, Peng Bai, Li Yang, Lijuan Chen, Zhoufeng Wang, Huili Liu, Xiaoming Shu, Jiaolin Wen
Publikováno v:
Current Pharmaceutical Design. 26:4338-4348
Background: PEGylation of stealth liposomes elevates their stability and prolongs plasma half-life. Stealth liposomes modified with targeting ligands are expected to be ideal drug delivery carriers. Objective: To encapsulate docetaxel in tbFGF (trunc
Autor:
Lijuan Chen, Junda Liu, Yingyu Ma, Neng Qiu, Xu Han, Teng Zhang, Xiu Zhao, Ziqin Li, Lianying An
Publikováno v:
European Journal of Pharmaceutical Sciences. 160:105745
Podophyllotoxin is a natural occurring aryltetralin lignin with pronounced cytotoxic activity. However, its clinical application for cancer treatment has been blocked due to its poor water solubility and selectivity. In this work, biotin as a tumor s
Autor:
Zitai Sang, Lijuan Chen, Tao Yang, Lianying An, Xuebing Li, Beilisha Shen, Xiaotong Zhang, Neng Qiu, Lan Wang, Junda Liu
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 85:289-301
The objective of this study was to investigate the effect of hydroxypropyl-β-cyclodextrin (HP-β-CD) on the water-solubility and stability of magnolol (MAG). The inclusion complex was prepared by a coevaporation strategy and the interactions of MAG