Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nemil Vora"'
Autor:
Linling He, Natalia de Val, Charles D. Morris, Nemil Vora, Therese C. Thinnes, Leopold Kong, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Ian A Wilson, David Nemazee, Andrew B. Ward, Jiang Zhu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The development of native-like envelope trimers has been a major focus in the efforts to produce HIV vaccines. Here the authors demonstrate the production and characterization of virus-like nanoparticles displaying trimeric HIV-1 antigens with the po
Externí odkaz:
https://doaj.org/article/6312ec547362425ea3f5f742d4a2358e
Autor:
Leopold Kong, Linling He, Natalia de Val, Nemil Vora, Charles D. Morris, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Andrew B. Ward, Ian A. Wilson, Jiang Zhu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
A major goal of HIV-1 vaccine development is to produce antigens that can induce broadly neutralizing antibodies. Here the authors examine the underlying causes of HIV-1 envelope metastability and design uncleaved, prefusion-optimized gp140 trimers w
Externí odkaz:
https://doaj.org/article/3cbbbe8afb93480b992188ff0d705f74
Autor:
Charles D. Morris, Parisa Azadnia, Natalia de Val, Nemil Vora, Andrew Honda, Erick Giang, Karen Saye-Francisco, Yushao Cheng, Xiaohe Lin, Colin J. Mann, Jeffrey Tang, Devin Sok, Dennis R. Burton, Mansun Law, Andrew B. Ward, Linling He, Jiang Zhu
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Broadly neutralizing antibodies (bNAbs) have provided valuable insights into the humoral immune response to HIV-1. While rationally designed epitope scaffolds and well-folded gp140 trimers have been proposed as vaccine antigens, a comparativ
Externí odkaz:
https://doaj.org/article/dbe193c7017d4d1bb2b716e824357db2
Autor:
Jeffrey Tang, Jiang Zhu, Charles D. Morris, Xiaohe Lin, Parisa Azadnia, Nemil Vora, Erick Giang, Dennis R. Burton, Karen L. Saye-Francisco, Yushao Cheng, Natalia de Val, Andrew Honda, Linling He, Devin Sok, Colin J. Mann, Andrew B. Ward, Mansun Law
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
mBio
mBio, Vol 8, Iss 1, p e00036-17 (2017)
mBio
mBio, Vol 8, Iss 1, p e00036-17 (2017)
Broadly neutralizing antibodies (bNAbs) have provided valuable insights into the humoral immune response to HIV-1. While rationally designed epitope scaffolds and well-folded gp140 trimers have been proposed as vaccine antigens, a comparative underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be7cc28bf819a3242c4c5d4438e64fa
https://doi.org/10.1128/mbio.00036-17
https://doi.org/10.1128/mbio.00036-17
Publikováno v:
Journal of the American Chemical Society. 135:9299-9302
The three-dimensional structure of the 81-residue mercury transporter MerF determined in liquid crystalline phospholipid bilayers under physiological conditions by Rotationally Aligned (RA) solid-state NMR has two long helices, which extend well beyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363075015b68216ffe39fa90ecff52bb
https://doi.org/10.1021/ja4042115
https://doi.org/10.1021/ja4042115
Autor:
Linling He, Leopold Kong, Jiang Zhu, Devin Sok, Nemil Vora, Parisa Azadnia, Dennis R. Burton, Charles D. Morris, Andrew B. Ward, Ian A. Wilson, Bin Zhou, Natalia de Val
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The trimeric HIV-1 envelope glycoprotein (Env) is critical for host immune recognition and neutralization. Despite advances in trimer design, the roots of Env trimer metastability remain elusive. Here we investigate the contribution of two Env region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b325bb69fd3dd8d282f2425da2c7f046
http://europepmc.org/articles/PMC4931249
http://europepmc.org/articles/PMC4931249