Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Nemil, Bhatt"'
Autor:
Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Musashi family of RNA binding proteins are found in an oligomeric state in the brains of patients with Alzheimer’s disease. Here the authors show that Mushashi1 and Musashi2 interact with tau protein in patient tissue and in models of tauopathy
Externí odkaz:
https://doaj.org/article/f852a7fca4c646d8bcc24eb27d1af230
Autor:
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt, Rakez Kayed
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract The transcription factor, p53, is critical for many important cellular functions involved in genome integrity, including cell cycle control, DNA damage response, and apoptosis. Disruption of p53 results in a wide range of disorders including
Externí odkaz:
https://doaj.org/article/89d5269d42b94a85852128d51a041c5f
Publikováno v:
Molecular Neurobiology. 60:2691-2705
The pathological hallmark of many neurodegenerative diseases is the accumulation of characteristic proteinaceous aggregates. Parkinson’s disease and dementia with Lewy bodies can be characterized as synucleinopathies due to the abnormal accumulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf78becee5ba641aa24135b74f5ccd3c
https://doi.org/10.1007/s12035-023-03211-3
https://doi.org/10.1007/s12035-023-03211-3
Autor:
Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105130- (2020)
Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in
Externí odkaz:
https://doaj.org/article/d9510ba996114ef685a27d88a84a1bf5
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The multifactorial and complex nature of Alzheimer's disease (AD) has made it difficult to identify therapeutic targets that are causally involved in the disease process. However, accumulating evidence from experimental and clinical studies that inve
Externí odkaz:
https://doaj.org/article/14de4fd35ac84c58a8cc989888c3172a
Autor:
Alice Bittar, Rabab Al-Lahham, Nemil Bhatt, Kenya Moore, Mauro Montalbano, Cynthia Jerez, Leiana Fung, Salome McAllen, Anna Ellsworth, Rakez Kayed
Publikováno v:
Journal of Alzheimer's Disease. 90:1103-1122
Background: Tau oligomers are one of the most toxic species, displaying prion-like strains which have different conformations resulting in different tauopathies. Passive immunotherapy targeting different tau species is a promising therapeutic approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b48476c529581443aed134e1f97643
https://doi.org/10.3233/jad-220518
https://doi.org/10.3233/jad-220518
Autor:
Mauro Montalbano, Leiana Fung, Nemil Bhatt, Sagar Gaikwad, Alice Bittar, Nicha Puangmalai, Urmi Sengupta, Rakez Kayed
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7389ba5f88cc0551e9ccfe18bf0c42
https://doi.org/10.1002/alz.062374
https://doi.org/10.1002/alz.062374
Autor:
Michela Marcatti, Anna Fracassi, Mauro Montalbano, Nicha Puangmalai, Nemil Bhatt, Chandramouli Natarajan, Jutatip Guptarak, Balaji Krishnan, Rakez Kayed, Giulio Taglialatela
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e917cc3b8df1cc705cb8a074cedb55c5
https://doi.org/10.1002/alz.062586
https://doi.org/10.1002/alz.062586
Autor:
Shailendra Dhakal, Alicia S. Robang, Nemil Bhatt, Nicha Puangamali, Leiana Fung, Rakez Kayed, Anant K. Paravastu, Vijayaraghavan Rangachari
Amyloid aggregates of specific proteins form important pathological hallmarks in many neurodegenerative diseases, defining neuronal degeneration and disease onset. Recently, increasing numbers of patients show co-morbidities and overlaps between mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f5683f01678eeb3882184f782887af
https://doi.org/10.1101/2022.06.14.496041
https://doi.org/10.1101/2022.06.14.496041
Autor:
Nemil Bhatt, Rakez Kayed
Publikováno v:
Cell reports. Medicine. 3(5)
A study by Kass et al.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8ac0772a194f66ed33e9ae01b7664c
https://pubmed.ncbi.nlm.nih.gov/35584632
https://pubmed.ncbi.nlm.nih.gov/35584632