Development of optically controlled "living electrodes" with long-projecting axon tracts for a synaptic brain-machine interface.

Autor: Adewole DO; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA., Struzyna LA; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA., Burrell JC; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA., Harris JP; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Nemes AD; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Petrov D; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Kraft RH; Computational Biomechanics Group, The Pennsylvania State University, University Park, PA 16802, USA., Chen HI; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Serruya MD; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA.; Neurodelphus LLC, 3401 Grays Ferry Ave., Unit 6176, Philadelphia, PA 19146, USA.; Nuromo LLC, 405 Meadow Lane, Merion Station, PA 19066, USA., Wolf JA; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA., Cullen DK; Center for Brain Injury and Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. dkacy@pennmedicine.upenn.edu.; Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA.; Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: Science advances [Sci Adv] 2021 Jan 22; Vol. 7 (4). Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).

Neuronal nitric oxide synthase and affective disorders.

Autor: Zhou QG; Department of Clinical Pharmacology, Pharmacy College, Nanjing Medical University, Nanjing 211166, PR China., Zhu XH; Department of Clinical Pharmacology, Pharmacy College, Nanjing Medical University, Nanjing 211166, PR China., Nemes AD; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, USA., Zhu DY; Department of Clinical Pharmacology, Pharmacy College, Nanjing Medical University, Nanjing 211166, PR China.

Publikováno v: IBRO reports [IBRO Rep] 2018 Nov 17; Vol. 5, pp. 116-132. Date of Electronic Publication: 2018 Nov 17 (Print Publication: 2018).

Treatment with lacosamide impedes generalized seizures in a rodent model of cortical dysplasia.

Autor: Nemes AD; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, U.S.A., O'Dwyer R; Department of Neurological Sciences, Rush Medical College, Chicago, Illinois, U.S.A., Najm IM; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, U.S.A., Ying Z; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, U.S.A., Gonzalez-Martinez J; Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio, U.S.A., Alexopoulos AV; Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, U.S.A.

Publikováno v: Epilepsia [Epilepsia] 2017 Oct; Vol. 58 (10), pp. 1755-1761. Date of Electronic Publication: 2017 Aug 20.