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Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation.

Autor: Ozohanics O; Department of Biochemistry, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary., Zhang X; Department of Chemistry, Rutgers University, Newark, NJ 07102, USA., Nemeria NS; Department of Chemistry, Rutgers University, Newark, NJ 07102, USA., Ambrus A; Department of Biochemistry, Institute of Biochemistry and Molecular Biology, Semmelweis University, 1094 Budapest, Hungary., Jordan F; Department of Chemistry, Rutgers University, Newark, NJ 07102, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 25; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 25.

E. coli and the etiology of human PBC: Antimitochondrial antibodies and spreading determinants.

Autor: Yang Y; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA.; School of Food Science and Pharmaceutical EngineeringNanjing Normal UniversityNanjingChina., Choi J; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA.; Division of RheumatologyCHA University Medical CenterBundangKorea., Chen Y; School of Food Science and Pharmaceutical EngineeringNanjing Normal UniversityNanjingChina., Invernizzi P; International Center for Digestive HealthDepartment of Medicine and SurgeryUniversity of Milan-BicoccaMilanItaly., Yang G; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA., Zhang W; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA., Shao TH; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA., Jordan F; Department of ChemistryRutgers UniversityNewarkNew JerseyUSA., Nemeria NS; Department of ChemistryRutgers UniversityNewarkNew JerseyUSA., Coppel RL; Department of Microbiology, Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia., Ridgway WM; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA., Kurth M; Department of ChemisrtyUniversity of California DavisDavisCaliforniaUSA., Ansari AA; Department of PathologyEmory University School of MedicineAtlantaGeorgiaUSA., Leung PSC; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA., Gershwin ME; Division of Rheumatology, Allergy and Clinical ImmunologyUniversity of California DavisDavisCaliforniaUSA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2022 Feb; Vol. 75 (2), pp. 266-279. Date of Electronic Publication: 2021 Dec 12.

Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.

Autor: Leandro J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Khamrui S; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Wang H; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Suebsuwong C; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Nemeria NS; Department of Chemistry, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, United States., Huynh K; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Moustakim M; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Secor C; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Wang M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Dodatko T; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Stauffer B; Mount Sinai Genomics, Inc, Stamford, Connecticut 06902, United States., Wilson CG; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States., Yu C; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Mount Sinai Genomics, Inc, Stamford, Connecticut 06902, United States., Arkin MR; Small Molecule Discovery Center and Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States., Jordan F; Department of Chemistry, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, United States., Sanchez R; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., DeVita RJ; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Drug Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Lazarus MB; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Houten SM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2020 Aug 21; Vol. 15 (8), pp. 2041-2047. Date of Electronic Publication: 2020 Jul 09.