Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nemanja Useinovic"'
Autor:
Omar Hoseá Cabrera, Nemanja Useinovic, Stefan Maksimovic, Michelle Near, Nidia Quillinan, Slobodan M. Todorovic, Vesna Jevtovic-Todorovic
Publikováno v:
Neurobiology of Disease, Vol 175, Iss , Pp 105923- (2022)
Preclinical models demonstrate that nearly all anesthetics cause widespread neuroapoptosis in the developing brains of infant rodents and non-human primates. Anesthesia-induced developmental apoptosis is succeeded by prolonged neuropathology in the s
Externí odkaz:
https://doaj.org/article/69fe6a65dbdd4959a6b3aa0287f446f5
Autor:
Francesca M. Manzella, Bethany F. Gulvezan, Stefan Maksimovic, Nemanja Useinovic, Yogendra H. Raol, Srdjan M. Joksimovic, Vesna Jevtovic-Todorovic, Slobodan M. Todorovic
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
General anesthetics are neurotoxic to the developing rodent and primate brains leading to neurocognitive and socio-affective impairment later in life. In addition, sleep patterns are important predictors of cognitive outcomes. Yet, little is known ab
Externí odkaz:
https://doaj.org/article/7257d81640974cecabbfea2144a4d7a5
Autor:
Nemanja Useinovic, Stefan Maksimovic, Cole Liechty, Omar H. Cabrera, Nidia Quillinan, Vesna Jevtovic-Todorovic
Publikováno v:
British Journal of Anaesthesia. 129:555-566
General anaesthesia in the neonatal period has detrimental effects on the developing mammalian brain. The impact of underlying inflammation on anaesthesia-induced developmental neurotoxicity remains largely unknown.Postnatal day 7 (PND7) rats were ra
Publikováno v:
Current Opinion in Anaesthesiology. 35:425-435
Steadily mounting evidence of anesthesia-induced developmental neurotoxicity has been a challenge in pediatric anesthesiology. Considering that presently used anesthetics have, in different animal models, been shown to cause lasting behavioral impair
Publikováno v:
British Journal of Anaesthesia.
Publikováno v:
Best Practice & Research Clinical Anaesthesiology.
Publikováno v:
Biol Reprod
Each year, millions of infants and children are anesthetized for medical and surgical procedures. Yet, a substantial body of preclinical evidence suggests that anesthetics are neurotoxins that cause rapid and widespread apoptotic cell death in the br
Autor:
Stefan Maksimovic, Nemanja Useinovic, Nidia Quillinan, Douglas F. Covey, Slobodan M. Todorovic, Vesna Jevtovic-Todorovic
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1889, p 1889 (2022)
Over the past three decades, we have been grappling with rapidly accumulating evidence that general anesthetics (GAs) may not be as innocuous for the young brain as we previously believed. The growing realization comes from hundreds of animal studies
Autor:
Nemanja Useinovic, Stefan Maksimovic, Michelle Near, Nidia Quillinan, Vesna Jevtovic-Todorovic
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1128, p 1128 (2022)
Since its invention, general anesthesia has been an indispensable component of modern surgery. While traditionally considered safe and beneficial in many pathological settings, hundreds of preclinical studies in various animal species have raised con
Autor:
Marko Vorkapić, Andrej Savić, Milica Janković, Nemanja Useinović, Milica Isaković, Nela Puškaš, Olivera Stanojlović, Dragan Hrnčić
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232530 (2020)
BACKGROUND:Clinical and animal studies have found that anxiety and depression are significantly more common after acute myocardial infarction (AMI). The medial prefrontal cortex (PFC) has a dual role: in higher brain functions and in cardiovascular c
Externí odkaz:
https://doaj.org/article/c13add1e55b5411e93afe4c68d642ae3