Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nely Rodríguez-Zhurbenko"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent years, in addition to the well-established role of T cells in controlling or promoting tumor growth, a new wave of research has demonstrated the active involvement of B cells in tumor immunity. B-cell subsets with distinct phenotypes and fu
Externí odkaz:
https://doaj.org/article/a2dc9c01a9fd48b88e48e7f572d7baf0
Autor:
Darel Martínez-Bedoya, Ana M Hernández-Vázquez, Teresa Rondón-Corrales, Tania Griñán-Ramirez, Nely Rodríguez-Zhurbenko, Amaury Pupo-Meriño, Lianet Cabrera-López, Judith Raymond-Pous, Ana M Vázquez-Gallo, Rolando Pérez-Rodríguez
Publikováno v:
Biotecnología Aplicada, Vol 35, Iss 2, Pp 2511-2513 (2018)
Externí odkaz:
https://doaj.org/article/61b21709e8b84bf2932832d587700ba7
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The traditional definition of natural antibodies (NAbs) states that these antibodies are present prior to the body encountering cognate antigen, providing a first line of defense against infection thereby, allowing time for a specific antibody respon
Externí odkaz:
https://doaj.org/article/fbf62f0a84bb4f88ae41f35599785451
Autor:
Mayrel Labrada, Ana María Hernández, Nely Rodríguez-Zhurbenko, Giselle Hevia, Luis E. Fernández, Ana María Vázquez, Denise Dorvignit
Publikováno v:
Seminars in Oncology. 45:41-51
Numerous molecules have been considered as targets for cancer immunotherapy because of their levels of expression on tumor cells, their putative importance for tumor biology, and relative immunogenicity. In this review we focus on the ganglioside GM3
Autor:
Thomas J. Hopkins, Tam D. Quach, Ana María Hernández, Thomas L. Rothstein, Nely Rodríguez-Zhurbenko
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Age-related deficits in the immune system have been associated with an increased incidence of infections, autoimmune diseases, and cancer. Human B cell populations change quantitatively and qualitatively in the elderly. However, the function of human
Autor:
Thomas L. Rothstein, Nely Rodríguez-Zhurbenko, Xiaoti Guo, Thomas J. Hopkins, Tam D. Quach, Wentian Li, Ana María Hernández
Publikováno v:
The Journal of Immunology. 196:1060-1069
Human antibody secreting cell (ASC) populations in circulation are not well studied. In addition to B-1 (CD20+CD27+CD38lo/intCD43+) cell and the conventional plasmablast (CD20-CD27hiCD38hi) cell populations, here we identified a novel B cell populati
Autor:
Darel Martínez, Maura Rabade-Chediak, Nely Rodríguez-Zhurbenko, Ana María Hernández, Tania Griñán
Publikováno v:
Annals of the New York Academy of Sciences. 1362:224-238
While not naturally expressed in normal human tissues, N-glycolylated (NeuGc) gangliosides are overexpressed in several tumors and have immunosuppressive capacity, which contributes to cancer progression. Naturally occurring antibodies against NeuGcG
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1643
Gangliosides are sialic acid-containing glycolipids that have been considered attractive targets for cancer immunotherapy, based on the qualitative and quantitative changes they suffer during malignant transformation and due to their importance for t
Autor:
Darel Martínez, Tania Griñán, Rancés Blanco, Teresa Rondón, Nely Rodríguez-Zhurbenko, Ana María Hernández
Publikováno v:
European Journal of Immunology. 43:826-837
N-glycolylated gangliosides are not naturally expressed in healthy human tissues but are overexpressed in several tumors. We demonstrate the existence of antibodies that bind (N-glycolylneuraminyl)-lactosylceramide (NeuGcGM3) and are detectable in th
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Only few studies have described the anti-tumor properties of natural antibodies (NAbs). In particular, natural IgM have been linked to cancer immunosurveillance due to its preferential binding to tumor-specific glycolipids and carbohydrate structures
Externí odkaz:
https://doaj.org/article/9c4c8b73b5be455e86ad5694c5ef1aef