Výsledky vyhledávání - "Nelson Murcar"

Booster immunization of HIV-1 negative volunteers with HGP-30 vaccine induces protection against HIV-1 virus challenge in SCID mice

Autor: Rebecca L. Coleman, Howard E. Gendelman, D Winship, Nelson Murcar, James O. Kahn, Prem S. Sarin, S Beckner, Linda S. Kelsey, P Heseltine, James E. Talmadge

Publikováno v: Vaccine. 17:64-71

Eleven HIV-1 seronegative subjects previously injected with an HIV-1 p17 synthetic peptide vaccine (HGP-30) were given two booster immunizations to evaluate memory cell responses and the ability to boost cellular and humoral immune responses. Five of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9293c59e8f9b91dbb9ff4c9d086ea059
https://doi.org/10.1016/s0264-410x(98)00119-4

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Clinical And Immunologic Responses To Human Immunodeficiency Virus (HIV) Type LSF2 gp120 Subunit Vaccine Combined With MF59 Adjuvant With Or Without Muramyl Tripeptide Dipalmitoyl Phosphatidylethanolamine In Non-HIV-Infected Human Volunteers

Autor: James O. Kahn, Kathelyn S. Steimer, Faruk Sinangil, Dee Wynne, Nelson Murcar, Rebecca L. Coleman, Juerg Baenziger, Cornelia L. Dekker, David Chernoff

Publikováno v: Journal of Infectious Diseases. 170:1288-1291

A phase 1 study of 42 non-human immunodeficiency virus type 1 (HIV)-infected volunteers was initiated to determine the safety and immunogenicity of an HIV subunit vaccine consisting of recombinant envelope gp120 derived from HIVSF2 (rgp120SF2) combin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c67bf530d6a344a4742f30f4c9032c2
https://doi.org/10.1093/infdis/170.5.1288

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Clinical, immunologic, and virologic observations related to human immunodeficiency virus (HIV) type 1 infection in a volunteer in an HIV-1 vaccine clinical trial

Autor: Kathelyn S. Steimer, Margaret A. Chesney, Nelson Murcar, Juerg Baenziger, David Chernoff, James O. Kahn, Tarek Elbeik, Faruk Sinangil, Mark B. Feinberg, Anne-Marie Duliege

Publikováno v: Scopus-Elsevier

A vaccine breakthrough occurred in a phase 1 clinical trial of a human immunodeficiency virus (HIV) type 1 candidate subunit vaccine. The vaccine antigen, gp120 SF2 , is a fully glycosylated protein produced in mammalian cells from the HIV SF2 isolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94086846d65420a212c6f5b72a72090
https://pubmed.ncbi.nlm.nih.gov/8568327

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A phase I study of HGP-30, a 30 amino acid subunit of the human immunodeficiency virus (HIV) p17 synthetic peptide analogue sub-unit vaccine in seronegative subjects

Autor: Paul A. Volberding, Vincent F. Simmon, James O. Kahn, Paul H. Naylor, Jim Scillian, Daniel P. Stites, Alan L. Goldstein, Nelson Murcar, Prem S. Sarin, Peter Heseltine, Richard Stryker, Su-San Wang

Publikováno v: AIDS research and human retroviruses. 8(8)

HGP-30-KLH vaccine in alum at doses of 10, 25, 50, and 100 micrograms/kg administered intramuscularly at weeks 0, 4, and 10 appear well-tolerated clinically. Local pain at the injection site, appears to be the main clinical toxicity. Laboratory param

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b237386ca76f698bc27a87259e66ba5a
https://pubmed.ncbi.nlm.nih.gov/1466950

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