Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nelson M Varela"'
Autor:
Daniela Liempi, Inés Zulantay, Nelson M. Varela, Mauricio Canals, Andrés Guevara, Nicolás Poulsen, Werner Apt
Publikováno v:
Microorganisms, Vol 12, Iss 2, p 249 (2024)
The objective of this study was to compare, by qPCR, the circulating blood parasite load of Trypanosoma cruzi in the buffy coat, and in whole blood mixed with boiled and unboiled guanidine hydrochloride-EDTA buffer, of individuals with chronic ChD. T
Externí odkaz:
https://doaj.org/article/2ed1a9be25d9478c82ecb2427808ed51
Autor:
Aimeé Salas-Hernández, Macarena Galleguillos, Matías Carrasco, Andrés López-Cortés, María Ana Redal, Dora Fonseca-Mendoza, Patricia Esperón, Farith González-Martínez, Ismael Lares-Asseff, Alberto Lazarowski, Verónica Loera-Castañeda, Diadelis Remírez, Matías F. Martínez, Rodrigo Vargas, Fabricio Rios-Santos, Antonio Macho, Juan P. Cayún, Germán R. Perez, Carolina Gutierrez, Leslie C. Cerpa, Tamara Leiva, Susan Calfunao, Lesly Xajil, Christopher Sandoval, Marcelo Suárez, Ariana Gonzalez, Gabriela Echeverría-Garcés, Luis Sullón-Dextre, Eugenia Cordero-García, Alexis R. Morales, Andrea Avendaño, Enrique Sánchez, Laura C. Bastone, Cesar Lara, Patricia Zuluaga-Arias, Ana María Soler, Julio Da Luz, Gabriela Burgueño-Rodríguez, Marcelo Vital, Elizabeth Reyes-Reyes, Alexander Huaccha, Yeimy V. Ariza, Naomi Tzul, Ana L. Rendón, Roberto Serrano, Larissa Acosta, Angelo Motta-Pardo, Leonardo Beltrán-Angarita, Erika Brand, Miguel A. Jiménez, Gladys Maribel Hidalgo-Lozada, Marina M. J. Romero-Prado, Karla Escobar-Castro, Mariel Umaña-Rivas, Juan D. Vivas, Paola Lagos, Yineth Ballén Martínez, Sharleth Quesada, Camila Calfio, Maria L. Arias, María A. Lavanderos, Dante D. Cáceres, Alberto Salazar-Granara, Nelson M. Varela, Luis A. Quiñones
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Pharmacogenomics (PGx) is considered an emergent field in developing countries. Research on PGx in the Latin American and the Caribbean (LAC) region remains scarce, with limited information in some populations. Thus, extrapolations are complicated, e
Externí odkaz:
https://doaj.org/article/cddef7cc0b5d4422b6589bf43ce85f02
Autor:
Andrés López-Cortés, Patricia Esperón, Matías F. Martínez, María A. Redal, Alberto Lazarowski, Nelson M. Varela, Ismael Lares-Asseff, Luis A. Quiñones
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7c8f53c45e614101a301fed05c339af6
Autor:
Patricio Gonzalez-Hormazabal, Diana Pelaez, Maher Musleh, Marco Bustamante, Juan Stambuk, Raul Pisano, Hector Valladares, Enrique Lanzarini, Hector Chiong, Jose Suazo, Luis A. Quiñones, Nelson M. Varela, V. Gonzalo Castro, Lilian Jara, Zoltan Berger
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-7 (2021)
Abstract Background Helicobacter pylori is detected by pathogen recognition receptors including toll-like receptors (TLR) and nucleotide-binding oligomerization domain (NOD)-like receptors, eliciting an innate immune response against this bacteria. T
Externí odkaz:
https://doaj.org/article/30bf55954e3447cbbb521dd2e2a60411
Autor:
Patricia Esperón, Matías F. Martínez, María A. Redal, Alberto Lazarowski, Andrés López-Cortés, Nelson M. Varela, Luis A. Quiñones
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/549cf8091bde4d80aa96fc2fb865e937
Autor:
Carla Miranda, Macarena Galleguillos, Roberto Torres, Karla Tardón, Dante D. Cáceres, Kuen Lee, María A. Redal, Nelson M. Varela, Luis A. Quiñones
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tamoxifen (TAM), a selective oestrogen receptor modulator, is one of the most used treatments in oestrogen receptor-positive (ER+) early and metastatic breast cancer (BC) patients. The response to TAM has a high degree of inter-individual variability
Externí odkaz:
https://doaj.org/article/f2e5127fbe534d109f3127cf26b36452
Autor:
Aimeé Salas-Hernández, Felipe Ruz-Cortés, Francisca Bruggendieck, Claudio Espinoza-Perez, Jenaro Espitia-Corredor, Nelson M. Varela, Luis A. Quiñones, Carlos Sánchez-Ferrer, Concepción Peiró, Guillermo Díaz-Araya
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111947- (2021)
Cardiac fibroblasts (CF) play an important role in the healing process and in pathological remodeling of cardiac tissue. As sentinel cells in the heart, they respond to inflammatory stimuli, expressing cytokines and cell adhesion proteins, which ulti
Externí odkaz:
https://doaj.org/article/7f05bda1d02e486caa525948dc1d4738
Autor:
Rodrigo M Young, Camila J Solis, Andres Barriga-Fehrman, Carlos Abogabir, Alvaro R Thadani, Mariana Labarca, Eva Bustamante, Cecilia V Tapia, Antonia G Sarda, Francisca Sepulveda, Nadia Pozas, Leslie C Cerpa, María A Lavanderos, Nelson M Varela, Alvaro Santibañez, Ana M Sandino, Felipe Reyes-Lopez, Garth Dixon, Luis A Quiñones
Publikováno v:
eLife, Vol 10 (2021)
The COVID-19 pandemic will likely take years to control globally, and constant epidemic surveillance will be required to limit the spread of SARS-CoV-2, especially considering the emergence of new variants that could hamper the effect of vaccination
Externí odkaz:
https://doaj.org/article/c46d5612e19347079878f1c807c5b0c2
Autor:
Daniela Poblete, Fernando Bernal, Gabriel Llull, Sebastian Archiles, Patricia Vasquez, Leonardo Chanqueo, Nicole Soto, María A. Lavanderos, Luis A. Quiñones, Nelson M. Varela
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, and atazanavir (ATV), a protease inhibitor, are drugs widely used in antiretroviral therapy (ART) for people living with HIV. These drugs have shown high interindividual v
Externí odkaz:
https://doaj.org/article/721b24516f4e4e2c92cc966af193fdf1
Autor:
Nelson M. Varela, Patricia Guevara-Ramírez, Cristian Acevedo, Tomás Zambrano, Isaac Armendáriz-Castillo, Santiago Guerrero, Luis A. Quiñones, Andrés López-Cortés
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Breast cancer (BRCA) and prostate cancer (PRCA) are the most commonly diagnosed cancer types in Latin American women and men, respectively. Although in recent years large-scale efforts from international consortia have focused on improvin
Externí odkaz:
https://doaj.org/article/7821b300318d4a229b13ea181abf0b2a