Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nelson L Jumbe"'
Autor:
Hana M Dobrovolny, Marc J Baron, Ronald Gieschke, Brian E Davies, Nelson L Jumbe, Catherine A A Beauchemin
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13811 (2010)
Several mechanisms have been proposed to account for the marked increase in severity of human infections with avian compared to human influenza strains, including increased cytokine expression, poor immune response, and differences in target cell rec
Externí odkaz:
https://doaj.org/article/4ce46c78807344fdb7682ba849b2ed55
Autor:
Nelson L. Jumbe, Michael H. Miller
Publikováno v:
Ophthalmic Drug Delivery Systems ISBN: 9781003113423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10ffe4b237d2948e7f738b203ff4e91
https://doi.org/10.4324/9781003113423-6
https://doi.org/10.4324/9781003113423-6
Publikováno v:
Clinical Pharmacokinetics. 55:93-105
Cabozantinib is a tyrosine kinase inhibitor approved in the USA and EU for the treatment of patients with progressive, metastatic medullary thyroid cancer (MTC). The indicated cabozantinib dose is 140 mg/day, with dose modifications allowed for patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c772621d59bd6adf5ac9df7a8b6e6880
https://doi.org/10.1007/s40262-015-0295-x
https://doi.org/10.1007/s40262-015-0295-x
Autor:
Hong Xiang, Mally Romero, Lisa A. Damico-Beyer, Judy Young, Mark Merchant, Elaine Mai, Amy C. Peterson, Ihsan Nijem, Nelson L. Jumbe, Brendan C. Bender, Arthur E. Reyes, Teresa Davancaze
Publikováno v:
Clinical Cancer Research. 19:5068-5078
Purpose: We characterized the pharmacokinetics of onartuzumab (MetMAb) in animals and determined a concentration–effect relationship in tumor-bearing mice to enable estimation of clinical pharmacokinetics and target doses. Experimental Design: A tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757a506f1986e9f1c2f96891d7be2c8c
https://doi.org/10.1158/1078-0432.ccr-13-0260
https://doi.org/10.1158/1078-0432.ccr-13-0260
Autor:
Nelson L. Jumbe, Suzana Tulac, Ernest Suchanek, Michael Toft Overgaard, Linda C. Giudice, A.E. Hamilton
Publikováno v:
Aalborg University
CONTEXT: Some members of the Wnt family, including ligands, receptors, inhibitors, and signaling components, are expressed in human endometrium. Dickkopf-1 (Dkk-1), a potent inhibitor of the Wnt signaling pathway, was recently found to be up-regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f449277fc9b44a34f77530d2ee37ef
https://doi.org/10.1210/jc.2005-0769
https://doi.org/10.1210/jc.2005-0769
Autor:
Joseph F. Grippo, Karin Jorga, Nelson L. Jumbe, E. N. Jonsson, Pascal Chanu, Nicolas Frey, Philippe Jacqmin, Marc Lavielle, Timothy Goggin, Eric Snoeck
Publikováno v:
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 2010, 87 (6), pp.706-713
Clinical Pharmacology and Therapeutics, 2010, 87 (6), pp.706-713
International audience; We propose a model that characterizes and links the complexity and diversity of clinically observed hepatitis C viral kinetics to sustained virologic response (SVR)--the primary clinical end point of hepatitis C treatment, def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86726e4369fdf18702ff72f661e20350
https://pubmed.ncbi.nlm.nih.gov/21270791
https://pubmed.ncbi.nlm.nih.gov/21270791
Autor:
Ronald Gieschke, Catherine A. A. Beauchemin, Nelson L. Jumbe, Hana M. Dobrovolny, Brian E. Davies
Publikováno v:
Journal of theoretical biology. 269(1)
Treatment of seasonal influenza viral infections using antivirals such as neuraminidase inhibitors (NAIs) has been proven effective if administered within 48 h post-infection. However, there is growing evidence that antiviral treatment of infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4dfcfefef69d4fe40bc5cf8e07fa9c
https://pubmed.ncbi.nlm.nih.gov/20970433
https://pubmed.ncbi.nlm.nih.gov/20970433
Autor:
William C. Fanslow, Vincent Chow, Nelson L. Jumbe, Benny Amore, Sonal K. Patel, Marc W. Retter
Publikováno v:
Cancer Research. 73:3359-3359
Background: AMG 172 is an antibody drug conjugate (ADC) comprised of a human IgG1 monoclonal antibody (mAb), a non-cleavable linker (4-[N-maleimidomethyl] cyclohexane-1-carboxylate) conjugated to lysine residues in the antibody and DM1, a semi-synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47dd696851d0326e15b090a5d1729b9c
https://doi.org/10.1158/1538-7445.am2013-3359
https://doi.org/10.1158/1538-7445.am2013-3359