Modeling the Effect of Binding Kinetics in Spatial Drug Distribution in the Brain

Autor: Verdiana Grace Masanja, Nelson Kashaju, Mark Kimathi

Publikováno v: Computational and Mathematical Methods in Medicine
Computational and Mathematical Methods in Medicine, Vol 2021 (2021)

A 3-dimensional mathematical model is developed to determine the effect of drug binding kinetics on the spatial distribution of a drug within the brain. The key components, namely, transport across the blood-brain barrier (BBB), drug distribution in

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