Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nelson J. Miles"'
Publikováno v:
Journal of Pharmaceutical Sciences. 69:1194-1198
A series of 1-(substituted benzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidones was synthesized primarily by catalytic hydrogenation of the corresponding 1-(substituted benzyl)-2(1H)-pyrimidone. The pharmacological evaluation of these compounds in mice revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791fbd893b0875b61efb15b3c591ec9e
https://doi.org/10.1002/jps.2600691020
https://doi.org/10.1002/jps.2600691020
Publikováno v:
Journal of Heterocyclic Chemistry. 13:973-976
2,4-Diphenyl-5-pyrimidinyl methyl ketone (8) and 2-phenyl-4-methyl-5-pyrimidinyl phenyl ketone (12) were prepared by condensation of benzamidine with 2-ethoxymethyl-1-phenyl-1,3-butanedione (10). Their structures were elucidated by the nmr spectra of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03f30f8cb835057310e76a964bc6489
https://doi.org/10.1002/jhet.5570130507
https://doi.org/10.1002/jhet.5570130507
Publikováno v:
Journal of Heterocyclic Chemistry. 11:849-851
The compound 5,6-dihydro-8-hydroxy-9-methoxy-1H,7H-benzo[ij]quinolizine-1,7-dione ( 4a) was synthesized from 3-(1,4-dihydro-6,7-dimethoxy-4-oxo-1-quinolyl)propionic acid (3a, free base), involving spontaneous demethylation with ring closure. The stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac7fc34ed5eb5f5c715587f66be29c52
https://doi.org/10.1002/jhet.5570110601
https://doi.org/10.1002/jhet.5570110601
Autor:
Thomas J. Schwan, Nelson J. Miles
Publikováno v:
Journal of Heterocyclic Chemistry. 19:1351-1353
The ring closure of N,N′-bis[2-(dialkoxy)ethyl]-p-xylene-α,α′-diamine dihydrochloride in fuming sulfuric acid has been investigated and the cyclization products have been identified as the linear pyrido[3,4-g]isoquinoline as well as the previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25e30fbb7416105fbf7bad070c46f71
https://doi.org/10.1002/jhet.5570190619
https://doi.org/10.1002/jhet.5570190619
Publikováno v:
Chemischer Informationsdienst. 12
A series of 1-(substituted benzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidonea was synthesized primarily by catalytic hydrogenation of the corresponding 1-(substituted benzyl)-2(1H)-pyrimidone. The pharmacological evaluation of these compounds in mice revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcde8a5680d8d1f8bb52bd1630649337
https://doi.org/10.1002/chin.198115261
https://doi.org/10.1002/chin.198115261
Publikováno v:
Journal of pharmaceutical sciences. 67(4)
The synthesis and anti-inflammatory activity of a series of 1-substituted 2-imidazolidinones are reported. These compounds exerted marked anti-inflammatory activity in the carrageenan-induced hindpaw edema assay in the rat in doses that failed to eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971c5a4e74d3d4db46b18e4514377f1f
https://pubmed.ncbi.nlm.nih.gov/641766
https://pubmed.ncbi.nlm.nih.gov/641766
Publikováno v:
Chemischer Informationsdienst. 9
The synthesis and anti-inflammatory activity of a series of 1-substituted 2-imidazolidinones are reported. These compounds exerted marked anti-inflammatory activity in the carrageenan-induced hindpaw edema assay in the rat in doses that failed to eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a0f0ce74184bb24fd8eb7e68a86051
https://doi.org/10.1002/chin.197839205
https://doi.org/10.1002/chin.197839205
Publikováno v:
Chemischer Informationsdienst. 11
4-Acetoxy -1,2,3,4 - tetrahydro - 2,2-dimethyl-6,7-methylenedioxyisoquinolinium iodide, an analog of acetylcholine, was synthesized and a pharmacological profile of its GI effects was compiled. The agent inhibited dog colonic contraction in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8bca85d6c78629fa09c4f84e8e0858
https://doi.org/10.1002/chin.198010273
https://doi.org/10.1002/chin.198010273
Publikováno v:
Journal of pharmaceutical sciences. 68(10)
4-Acetoxy -1,2,3,4 - tetrahydro - 2,2-dimethyl-6,7-methylenedioxyisoquinolinium iodide, an analog of acetylcholine, was synthesized and a pharmacological profile of its GI effects was compiled. The agent inhibited dog colonic contraction in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37bdcc21a1bc80008c644f4448f9d13
https://pubmed.ncbi.nlm.nih.gov/512872
https://pubmed.ncbi.nlm.nih.gov/512872
Autor:
Thomas J. Schwan, Nelson J. Miles
Publikováno v:
Journal of Heterocyclic Chemistry. 19:1257-1258
Base catalyzed cyclization of ethyl 4-[2-(2-amino-4,5-dimethoxyphenyl)ethyl]-2-phenylpyrimidine-5-carboxylate, derived from ethyl 4-methyl-2-phenyl-5-pyrimidinecarboxylate and 3,4-dimethoxy-6-nitrobenz-aldehyde, gave 5,6-dihydro-8,9-dimethoxy-3-pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82901d74f8fcb6ea2adf366b38c8696b
https://doi.org/10.1002/jhet.5570190561
https://doi.org/10.1002/jhet.5570190561