Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nelson H, Gabilan"'
Publikováno v:
Pharmacological Reports. 72:563-570
Experimental and clinical studies indicate that neuronal death with the presence of high levels of reactive oxygen species are present in depressed patients and antidepressants might display neuroprotective effects against them. However, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa8d68f997b6cbbc2e848ac5ddf3b4c
https://doi.org/10.1007/s43440-019-00009-w
https://doi.org/10.1007/s43440-019-00009-w
Autor:
Daiane Fátima Engel, Jade de Oliveira, Vicente Lieberknecht, Ana Lúcia S. Rodrigues, Andreza Fabro de Bem, Nelson H. Gabilan
Publikováno v:
Neurochemical Research. 43:387-396
The contribution of oxidative stress to the pathophysiology of depression has been described in numerous studies. Particularly, an increased production of reactive oxygen species (ROS) caused by mitochondrial dysfunction can lead to neuronal cell dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c603d4266438bd2d5fc225daa240fa
https://doi.org/10.1007/s11064-017-2433-3
https://doi.org/10.1007/s11064-017-2433-3
Autor:
Camila Tiefensee Ribeiro, Eslen Delanogare, Samantha C. Lopes, Daiane Fátima Engel, Eduardo Luiz Gasnhar Moreira, Daniel Pens Gelain, Nelson H. Gabilan, Jade de Oliveira, Helen M. Melo, Andreza Fabro de Bem, José Cláudio Fonseca Moreira, Rui Daniel Prediger, Gabriela Cristina de Paula, Sergio T. Ferreira
Publikováno v:
Journal of Alzheimer's disease : JAD. 73(2)
Familial hypercholesterolemia (FH) is a genetic disorder caused by dysfunction of low density lipoprotein receptors (LDLr), resulting in elevated plasma cholesterol levels. FH patients frequently exhibit cognitive impairment, a finding recapitulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cc85ca706125cf2c6c4e85cd7ff558
https://pubmed.ncbi.nlm.nih.gov/31815695
https://pubmed.ncbi.nlm.nih.gov/31815695
Publikováno v:
Pharmacological reports : PR. 72(3)
Experimental and clinical studies indicate that neuronal death with the presence of high levels of reactive oxygen species are present in depressed patients and antidepressants might display neuroprotective effects against them. However, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::497b6cf354b0b7854e5708bff0274ac8
https://pubmed.ncbi.nlm.nih.gov/32240535
https://pubmed.ncbi.nlm.nih.gov/32240535
Autor:
Nelson H. Gabilan, Mauricio P. Cunha, Gislaine Olescowicz, Carla I. Tasca, Fabiana K. Ludka, Vicente Lieberknecht, Ana Lúcia S. Rodrigues, Ana B. Ramos-Hryb
Publikováno v:
Neurochemistry International. 95:4-14
Creatine has been reported to exert beneficial effects in several neurodegenerative diseases in which glutamatergic excitotoxicity and oxidative stress play an etiological role. The purpose of this study was to investigate the protective effects of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de342d128c29c3a9504bc4c211e52c76
https://doi.org/10.1016/j.neuint.2016.01.002
https://doi.org/10.1016/j.neuint.2016.01.002
Autor:
Nelson H. Gabilan, Mauricio P. Cunha, Daiane Fátima Engel, Ana Lúcia S. Rodrigues, Andréa D.E. Zomkowski
Publikováno v:
Pharmacology Biochemistry and Behavior. 103:408-417
Duloxetine is a selective serotonin and noradrenaline reuptake inhibitor used as antidepressant. However, its mechanisms of action are not fully understood. This study investigated the effect of duloxetine in the mouse forced swimming test (FST) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5631a0f81710b352fc421e8407db2817
https://doi.org/10.1016/j.pbb.2012.09.011
https://doi.org/10.1016/j.pbb.2012.09.011
Autor:
Rossana C. Soletti, Sirlei Daffre, Nelson H. Gabilan, Antonio Miranda, Laura del Barrio, Helena L. Borges, Manuela G. López, Vivaldo Moura-Neto
Publikováno v:
Chemico-Biological Interactions. 186:135-143
Gomesin is an antimicrobial peptide isolated from hemocytes of a common Brazilian tarantula spider named Acanthoscurria gomesiana. This peptide exerts antitumor activity in vitro and in vivo by an unknown mechanism. In this study, the cytotoxic mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a6b29ba50f7cb76140c2d84d81ff93
https://doi.org/10.1016/j.cbi.2010.04.012
https://doi.org/10.1016/j.cbi.2010.04.012
Autor:
Giselle Pinto de Faria, Gregor Anderluh, Vivaldo Moura-Neto, Nelson H. Gabilan, Hernán Terenzi, Helena L. Borges, Javier Vernal, Rossana C. Soletti
Publikováno v:
Anti-Cancer Drugs. 19:517-525
The search for new drugs and treatment approaches is of particular importance for glioblastomas (GBMs), as with other types of malignant gliomas, as they are lethal without the available medical care. Current anticancer cocktails have failed to prolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c3ae14f106f6951eb453538cf94820
https://doi.org/10.1097/cad.0b013e3282faa704
https://doi.org/10.1097/cad.0b013e3282faa704
Autor:
Adair R.S. Santos, Patricia S. Brocardo, Rafael Trevisan, Alcir Luiz Dafre, Ana Lúcia S. Rodrigues, Nelson H. Gabilan, Jeferson Luis Franco, Marcelo Farina, Thaís Posser, Marcela Uliano-Silva, Rodrigo B. Leal
Publikováno v:
Behavioural Brain Research. 188:316-323
We investigated the antidepressant-like effect of zinc chloride (zinc) administered acutely during 7 days (i.p. route), or chronically during 30 days (oral route) in the forced swimming test (FST) in rats. It was also investigated whether the antidep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c37bdde864eed4fa4578820f383c23
https://doi.org/10.1016/j.bbr.2007.11.012
https://doi.org/10.1016/j.bbr.2007.11.012
Autor:
Ana Lúcia S. Rodrigues, Nelson H. Gabilan, Rúbia C. Almeida, Manuela G. López, Cristiane S. Felisbino
Publikováno v:
Behavioural Brain Research. 168:318-322
This study investigated the involvement of the L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) pathway in the antidepressant-like effect of an acute administration of memantine in the forced swimming test (FST) in mice, since this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e091b4566d68d00d9d7df39dd2c0c6f8
https://doi.org/10.1016/j.bbr.2005.11.023
https://doi.org/10.1016/j.bbr.2005.11.023