Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling

Autor: Erin Piazza, Isgur L, Lasley Ae, Nelson Js, Appelbe O, Joseph M. Beechem, Yan Liang, Maddy Griswold, Klock A, Kulasekara Br, Margaret L. Hoang, Buhr Dl, Huynh Q, Daniel R. Zollinger, Karen Nguyen, Kutchma A, Zimmerman Sm, Arya Bahrami, Kit Fuhrman, Rininger A, Robin Fropf, Rich Boykin, Jill McKay-Fleisch, Michael Rhodes

Publikováno v: Genome research. 32(10)

Emerging spatial profiling technology has enabled high-plex molecular profiling in biological tissues, preserving the spatial and morphological context of gene expression. Here we describe expanding the chemistry for the Digital Spatial Profiling pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75a0ada7e6cd4eb6a2647257fb067d1
https://pubmed.ncbi.nlm.nih.gov/36100434

Ultrastructural characterization of hyperactive endothelial cells, pericytes and fibroblasts in hypertrophic and nodular port-wine stain lesions

Autor: Gao, L, Yin, R, Wang, H, Guo, W, Song, W, Nelson, JS, Tan, W, Wang, G

Publikováno v: Gao, L; Yin, R; Wang, H; Guo, W; Song, W; Nelson, JS; et al.(2017). Ultrastructural characterization of hyperactive endothelial cells, pericytes and fibroblasts in hypertrophic and nodular port-wine stain lesions. British Journal of Dermatology, 177(4), e105-e108. doi: 10.1111/bjd.15373. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6bn0g039

Port wine stain (PWS) is a congenital vascular malformation of human skin involving the superficial vascular plexus,1-4 but the molecular pathogenesis of these lesions remains incompletely understood.5-8 We herein performed a transmission electron mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d668b63466694882d930bd875843938c
http://www.escholarship.org/uc/item/6bn0g039

The somatic GNAQ mutation (R183Q) is primarily located within the blood vessels of port wine stains

Autor: Tan, W, Nadora, DM, Gao, L, Wang, G, Mihm, MC, Nelson, JS

Publikováno v: Journal of the American Academy of Dermatology, vol 74, iss 2
Tan, W; Nadora, DM; Gao, L; Wang, G; Mihm, MC; & Nelson, JS. (2016). The somatic GNAQ mutation (R183Q) is primarily located within the blood vessels of port wine stains. Journal of the American Academy of Dermatology, 74(2), 380-383. doi: 10.1016/j.jaad.2015.09.063. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/13r8167c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::21010692fe016f878b8fcf1c4e5ebb53
https://escholarship.org/uc/item/13r8167c

Topical axitinib suppresses angiogenesis pathways induced by pulsed dye laser

Autor: Gao, L, Nadora, DM, Phan, S, Chernova, M, Sun, V, Preciado, SMO, Jia, W, Wang, G, Mihm, MC, Nelson, JS, Tan, W

Publikováno v: British Journal of Dermatology, vol 172, iss 3
Gao, L.; Nadora, D.M.; Phan, S.; Chernova, M.; Sun, V.; Preciado, S.M.O.; et al.(2015). Topical axitinib suppresses angiogenesis pathways induced by pulsed dye laser. British Journal of Dermatology, 172(3), 669-676. doi: 10.1111/bjd.13439. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/4wn996g3
Gao, L; Nadora, DM; Phan, S; Chernova, M; Sun, V; Preciado, SMO; et al.(2015). Topical axitinib suppresses angiogenesis pathways induced by pulsed dye laser. British Journal of Dermatology, 172(3), 669-676. doi: 10.1111/bjd.13439. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6q00h544

© 2014 British Association of Dermatologists. Background The recurrence of port-wine stain (PWS) blood vessels by pulsed dye laser (PDL)-induced angiogenesis is a critical barrier that must be overcome to achieve a better therapeutic outcome. Object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::03024415a93d60e64136a57de5de3faa
https://escholarship.org/uc/item/6q00h544

Effects of ICG concentration on the optical properties of erythrocyte-derived nano-vectors

Autor: Tang, J, Bahmani, B, Burns, J, Nuñez, V, Mac, J, Bacon, D, Vullev, V, Sun, V, Jia, W, Nelson, JS, Anvari, B

Publikováno v: Tang, J; Bahmani, B; Burns, J; Nuñez, V; Mac, J; Bacon, D; et al.(2015). Effects of ICG concentration on the optical properties of erythrocyte-derived nano-vectors. Progress in Biomedical Optics and Imaging-Proceedings of SPIE, 9341. doi: 10.1117/12.2079796. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6qg4z3zp

© 2015 SPIE. Erythrocyte-based nanoparticle platforms can offer long circulation times not offered by traditional drug delivery methods. We have developed a novel erythrocyte-based nanoparticle doped with indocyanine green (ICG), the only FDA-approv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d3952c8a90bd28d5d99222b6cd337c82
http://www.escholarship.org/uc/item/6qg4z3zp