Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nelson, Hsia"'
Autor:
Gail A. Cornwall, Barry T. Hinton, Jacquelyn C. Labus, Ling Yang, Nelson Hsia, R. John Lye, Richard N. Day, Jennifer L. Kirby
Publikováno v:
Biology of Reproduction. 71:613-619
The mammalian epididymis plays a critical role in sperm maturation, a function dependent on testicular androgens. However, the function of the initial segment, the most proximal part of the epididymis, is also dependent on luminal factors of testicul
Autor:
Nelson Hsia, Gail A. Cornwall
Publikováno v:
Biology of Reproduction. 70:448-457
Microarray analysis was carried out to identify genes with enriched expression in the initial segment region of the mouse epididymis. A set of approximately 15 000 clones developed at the National Institutes for Aging and consisting of expressed sequ
Autor:
Andrea Wagenfeld, Patrick Vernet, Joël R. Drevet, Nelson Hsia, Gail A. Cornwall, Marie-Claire Orgebin-Crist, Ching-Hei Yeung, Cosmina Avram, Sin Tak Chu, Eberhard Nieschlag, Trevor G. Cooper
Publikováno v:
Biology of Reproduction. 69:1750-1762
Transgenic male mice bearing inactive mutations of the receptor tyrosine kinase c-ros lack the initial segment of the epididymis and are infertile. Several techniques were applied to determine differences in gene expression in the epididymal caput of
Publikováno v:
Endocrinology. 144:901-908
The cystatin-related epididymal spermatogenic (CRES) protein is related to the family 2 cystatins of the cystatin superfamily of cysteine protease inhibitors. However, CRES lacks sequences important for cysteine protease inhibitory activity and is sp
Autor:
Nelson Hsia, Gail A. Cornwall
Publikováno v:
Molecular and Cellular Endocrinology. 200:1-8
The cystatins are a superfamily of cysteine protease inhibitors. Several genes including Cres (cystatin-related epididymal spermatogenic), testatin, and cystatin T, have been identified that are related to the family 2 cystatins but lack critical con
Autor:
Patrick Syntin, Daniel M. Hardy, Michael J. Wassler, Nelson Hsia, H. G. Sutton‐Walsh, Gail A. Cornwall
Publikováno v:
Biology of Reproduction. 67:795-803
Our earlier studies in mouse have shown that the cystatin-related epididymal spermatogenic (CRES) protein is highly expressed in elongating spermatids in the testis and is present in mouse sperm acrosomes, suggesting specific roles in sperm function,
Autor:
Gail A. Cornwall, Nelson Hsia
Publikováno v:
Biology of Reproduction. 65:1452-1461
The CRES protein is a member of the cystatin superfamily of cysteine protease inhibitors with restricted expression in stage-specific germ cells, proximal caput epididymidis, and anterior pituitary gonadotroph cells. To elucidate the molecular mechan
Publikováno v:
Biology of Reproduction. 64:1600-1607
The myc family of transcriptional regulators carries out critical roles in the control of cellular proliferation, differentiation, apoptosis, and tumorigenesis. The B-myc gene is a recently identified myc family member that has not been well characte
Autor:
Nelson Hsia, Gail A. Cornwall
Publikováno v:
Endocrinology. 138:4262-4272
The maturation of spermatozoa in the epididymis is a complex process that requires the active involvement of the epididymal epithelium. The primary focus toward elucidating the role of the epididymis in the maturation process has been the study of ep
Autor:
Johannes Everse, Nelson Hsia
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 24:533-551
It is well known that hemoglobin (Hb) possesses many oxidative enzyme activities, including a pseudo-peroxidase activity. It has also been shown by many investigators that various peroxidases in the presence of hydrogen peroxide and a halide ion exer