Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with [ ¹¹ C]UCB-J PET.

Autor: Young JJ; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; VA Connecticut Healthcare System, West Haven, Connecticut., O'Dell RS; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Naganawa M; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Toyonaga T; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Chen MK; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Nabulsi NB; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Huang Y; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Cooper E; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Miller A; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Lam J; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut., Bates K; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut., Ruan A; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Nelsen K; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Salardini E; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut., Carson RE; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., van Dyck CH; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut; and.; Department of Neurology, Yale School of Medicine, New Haven, Connecticut., Mecca AP; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut; adam.mecca@yale.edu.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2024 Nov 01; Vol. 65 (11), pp. 1782-1785. Date of Electronic Publication: 2024 Nov 01.