Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis.

Autor: Chegou NN; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa. novel@sun.ac.za., Sutherland JS; Vaccines and Immunity, Medical Research Council Unit, Fajara, The Gambia., Namuganga AR; Uganda-Case Western Research Collaboration - Makerere University, PO Box 663, Kampala, Uganda., Corstjens PL; Department of Molecular Cell Biology, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands., Geluk A; Department of Infectious Diseases, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands., Gebremichael G; Ethiopian Public Health Institute, Addis Ababa, Ethiopia., Mendy J; Vaccines and Immunity, Medical Research Council Unit, Fajara, The Gambia., Malherbe S; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Stanley K; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., van der Spuy GD; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Kriel M; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Loxton AG; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Kriel B; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Simukonda F; Karonga Prevention Study, Chilumba, Malawi.; URC Malawi Lab Project, PO Box 1921, Lilongwe, Malawi., Bekele Y; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Sheehama JA; School of Medicine, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia., Nelongo J; School of Medicine, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia., van der Vyver M; School of Medicine, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia., Gebrexabher A; Ethiopian Public Health Institute, Addis Ababa, Ethiopia., Hailu H; Ethiopian Public Health Institute, Addis Ababa, Ethiopia., Esterhuyse MM; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany., Rosenkrands I; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, 2300s, Denmark., Aagard C; Department of Infectious Disease Immunology, Statens Serum Institut, Copenhagen, 2300s, Denmark., Kidd M; Centre for Statistical Consultation, Department of Statistics and Actuarial Sciences, Stellenbosch University, Cape Town, South Africa., Kassa D; Department of Infectious Diseases, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands., Mihret A; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Howe R; Armauer Hansen Research Institute, Addis Ababa, Ethiopia., Cliff JM; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Crampin AC; Karonga Prevention Study, Chilumba, Malawi., Mayanja-Kizza H; Vaccines and Immunity, Medical Research Council Unit, Fajara, The Gambia., Kaufmann SHE; Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117, Berlin, Germany., Dockrell HM; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK., Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands., Walzl G; DST/NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa. gwalzl@sun.ac.za.

Publikováno v: Scientific reports [Sci Rep] 2018 Feb 08; Vol. 8 (1), pp. 2675. Date of Electronic Publication: 2018 Feb 08.