Hypotension and Hypocapnia During General Anesthesia in Piglets: Study of S100b as an Acute Biomarker for Cerebral Tissue Injury

Autor: Nelly Spielmann, Steen Antonsen, Tom Hansen, Simone K Ringer, Markus Weiss, Nicola Groes Clausen

Publikováno v: Clausen, N G, Antonsen, S, Spielmann, N, Hansen, T G, Weiss, M & Ringer, S K 2020, ' Hypotension and Hypocapnia During General Anesthesia in Piglets: Study of S100b as an Acute Biomarker for Cerebral Tissue Injury. ', Journal of Neurosurgical Anesthesiology, vol. 32, no. 3, pp. 273-278 . https://doi.org/10.1097/ANA.0000000000000601

BACKGROUND: Hypotension and/or hypocapnia might increase general anesthesia (GA)-related neuromorbidity in infants, but safe levels of perioperative blood pressure are poorly defined. Serum protein S100b has been used as screening, monitoring, and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36edff2fc4ac0eede95d642484e53543
https://portal.findresearcher.sdu.dk/da/publications/fe5cde4e-eeeb-400e-9011-03eaf4bc4e57

Effects of hypotension and/or hypocapnia during sevoflurane anesthesia on perfusion and metabolites in the developing brain of piglets-a blinded randomized study

Autor: Inés Carrera, Jacqueline Mauch, Stefanie Ohlerth, Markus Weiss, Simone K Ringer, Regula Bettschart-Wolfensberger, Nelly Spielmann

Publikováno v: Pediatric Anesthesia. 26:909-918

BACKGROUND: Hypotension (HT) and/or hypocapnia (HC) are frequent complications occurring during pediatric anesthesia and may cause cerebral injury in the developing brain. AIM: The aim of this study is to investigate the effects of HT and/or HC on pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0615857e0e8e85ecbbc15c2bc1187b
https://doi.org/10.1111/pan.12956

Comparison of conventional ROTEM®cups and pins to the ROTEM®cup and pin mini measuring cells (MiniCup)

Autor: Nelly Spielmann, Thorsten Haas, Melissa M. Cushing, Claudia M. Dillier, Svenja Siegmund, Bernard Krüger

Publikováno v: Scandinavian Journal of Clinical and Laboratory Investigation. 75:470-475

Thromboelastometry (ROTEM®) is a well-established measurement to guide perioperative coagulation management. Recently, an enhancement for low volume specimens using cup and pin mini measuring cells (MiniCup) was invented for scientific non-clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b9002c5d1e0a3be4da102d72d67b15
https://doi.org/10.3109/00365513.2015.1042909

Intraoperative music application in children and adolescents - a pilot study

Autor: Nelly Spielmann, Sabin Buehrer, Markus Weiss, Philipp K. Buehler, Achim Schmitz, Alexander R. Schmidt

Publikováno v: Acta anaesthesiologica Scandinavica. 61(8)

Background Hospitalization, surgery and anaesthesia may lead to new-onset maladaptive behaviour, emotional distress and trauma. This pilot study aims to investigate the influence of intraoperatively applied music on post-operative behaviour in childr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ef80b2b2df182e7393114e76b0d167
https://pubmed.ncbi.nlm.nih.gov/28685824

Do lower cuff pressures reduce damage to the tracheal mucosa? A scanning electron microscopy study in neonatal pigs

Autor: Nelly Spielmann, Jacqueline Mauch, Urs Ziegler, Annette P N Kutter, Regula Bettschart-Wolfensberger, Sonja Hartnack, Anne Greet Bittermann, Markus Weiss

Publikováno v: Pediatric Anesthesia. 23:117-121

BACKGROUND: Modern high volume-low pressure (HVLP) endotracheal tubes (ETT) cuffs can seal the trachea using baseline cuff pressures (CP) lower than peak inspiratory airway pressures (PIP). The aim of the study was to determine whether this technique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cd776dfcb1b4a49313d95411bc1a18
https://doi.org/10.1111/pan.12066