Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nelly Said"'
Autor:
Nelly Said, Mark Finazzo, Tarek Hilal, Bing Wang, Tim Luca Selinger, Daniela Gjorgjevikj, Irina Artsimovitch, Markus C. Wahl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transcription termination factor ρ is a hexameric, RNA-dependent NTPase that can adopt active closed-ring and inactive open-ring conformations. The Sm-like protein Rof, a homolog of the RNA chaperone Hfq, inhibits ρ-dependent termination i
Externí odkaz:
https://doaj.org/article/ef0791a398054336b30478c4f1f54dd0
Autor:
Philipp K. Zuber, Nelly Said, Tarek Hilal, Bing Wang, Bernhard Loll, Jorge González-Higueras, César A. Ramírez-Sarmiento, Georgiy A. Belogurov, Irina Artsimovitch, Markus C. Wahl, Stefan H. Knauer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract RfaH, a paralog of the universally conserved NusG, binds to RNA polymerases (RNAP) and ribosomes to activate expression of virulence genes. In free, autoinhibited RfaH, an α-helical KOW domain sequesters the RNAP-binding site. Upon recruitm
Externí odkaz:
https://doaj.org/article/22619a1bbf0f4160960efd35b3c7e5a0
Autor:
Hao-Hong Pei, Tarek Hilal, Zhuo A. Chen, Yong-Heng Huang, Yuan Gao, Nelly Said, Bernhard Loll, Juri Rappsilber, Georgiy A. Belogurov, Irina Artsimovitch, Markus C. Wahl
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The bacterial helicase-like transcription factor HelD interacts with the RNA polymerase (RNAP) and together with the RNAP δ subunit enhances RNAP cycling. Here, the authors present the cryo-EM structures of the monomeric and dimeric Bacillus subtili
Externí odkaz:
https://doaj.org/article/862de4900b514335855420b64fe9f8ae
Autor:
Maura Mittermeier, Bing Wang, Nelly Said, Daniela Gjorgjevikj, Markus C. Wahl, Irina Artsimovitch
Publikováno v:
Mol Microbiol
Escherichia coli RfaH abrogates Rho-mediated polarity in lipopolysaccharide core biosynthesis operons, and ΔrfaH cells are hypersensitive to antibiotics, bile salts, and detergents. Selection for rfaH suppressors that restore growth on SDS identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900d336d70e6186867bd2a9d72586893
https://doi.org/10.1111/mmi.14879
https://doi.org/10.1111/mmi.14879
Autor:
Verena Nadin Fritsch, Nico Linzner, Tobias Busche, Nelly Said, Christoph Weise, Jörn Kalinowski, Markus C. Wahl, Haike Antelmann
Streptococcus pneumoniae has to cope with the strong oxidant hypochlorous acid (HOCl), during host–pathogen interactions. Thus, we analyzed the global gene expression profile of S. pneumoniae D39 towards HOCl stress. In the RNA-seq transcriptome, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9dd1f3912576620f4108cd3710c62b
Publikováno v:
Zagazig University Medical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ff2f3f009767d20100bd10626c052c5
https://doi.org/10.21608/zumj.2022.123243.2484
https://doi.org/10.21608/zumj.2022.123243.2484
Autor:
nelly said
Publikováno v:
Zagazig University Medical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60fb43647aa2255a95657b8499333cca
https://doi.org/10.21608/zumj.2022.119795.2468
https://doi.org/10.21608/zumj.2022.119795.2468
Autor:
Markus C. Wahl, Nelly Said
Publikováno v:
Transcription
article-version (VoR) Version of Record
article-version (VoR) Version of Record
To exert their functions, RNAs adopt diverse structures, ranging from simple secondary to complex tertiary and quaternary folds. In vivo, RNA folding starts with RNA transcription, and a wide variety of processes are coupled to co-transcriptional RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acaea3edf1dea0e32d6e7174fc5dca7a
http://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=105163
http://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=105163
Autor:
Ajay Khatri, Nicholas D. Sunday, Nelly Said, Jörg Bürger, Ranjan Sen, Markus C. Wahl, Irina Artsimovitch, Bernhard Loll, Georgiy A. Belogurov, Thorsten Mielke, T. Hilal
Publikováno v:
Science
How to stop RNA polymerase Timely and tunable cessation of RNA synthesis is vital for cellular homeostasis. RNA helicases such as the archetypal termination factor r actively dismantle transcription complexes, but the transitory nature of termination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd82ecabfd3fa1d7a4550cd251d473c9
https://doi.org/10.1126/science.abd1673
https://doi.org/10.1126/science.abd1673
Autor:
Yuan Gao, Zhuo Chen, Yong-Heng Huang, Juri Rappsilber, Nelly Said, Markus C. Wahl, Bernhard Loll, Hao-Hong Pei, T. Hilal, Georgiy A. Belogurov, Irina Artsimovitch
Cellular RNA polymerases can become trapped on DNA or RNA, threatening genome stability and limiting free enzyme pools, or enter dormancy. How RNA polymerase recycling into active states is achieved and balanced with quiescence remains elusive. We st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea252ea99a95f7e042838d760cb5fe7
https://doi.org/10.21203/rs.3.rs-40617/v1
https://doi.org/10.21203/rs.3.rs-40617/v1