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pro vyhledávání: '"Nelly Saber"'
Autor:
Jennifer E. Bruin, Nelly Saber, Natalie Braun, Jessica K. Fox, Majid Mojibian, Ali Asadi, Campbell Drohan, Shannon O’Dwyer, Diana S. Rosman-Balzer, Victoria A. Swiss, Alireza Rezania, Timothy J. Kieffer
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 605-620 (2015)
Human embryonic stem cell (hESC)-derived pancreatic progenitor cells effectively reverse hyperglycemia in rodent models of type 1 diabetes, but their capacity to treat type 2 diabetes has not been reported. An immunodeficient model of type 2 diabetes
Externí odkaz:
https://doaj.org/article/054c9233aa8a42bb87c0b24cb06eb7b0
Autor:
Nelly Saber, Cara E. Ellis, Diepiriye G. Iworima, Robert K. Baker, Alireza Rezania, Timothy J. Kieffer
Publikováno v:
Diabetes. 72:590-598
Few studies have examined the differentiation of human embryonic stem cell (hESC)–derived pancreatic endoderm cells (PECs) in different implantation sites. Here, we investigate the influence of implantation site and recipient sex on the differentia
Autor:
Jennifer E. Bruin, Timothy J. Kieffer, Hellen Schuster, Shannon O'Dwyer, Alireza Rezania, Nelly Saber
Publikováno v:
Endocrinology. 159:1827-1841
Pancreatic progenitors derived from human embryonic stem cells (hESCs) are now in clinical trials for insulin replacement in patients with type 1 diabetes. Animal studies indicate that pancreatic progenitor cells can mature into a mixed population of
Autor:
Victoria A. Swiss, Ali Asadi, Jessica K. Fox, Shannon O'Dwyer, Campbell Drohan, Majid Mojibian, Jennifer E. Bruin, Timothy J. Kieffer, Natalie Braun, Alireza Rezania, Nelly Saber, Diana S. Rosman-Balzer
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 4, Iss 4, Pp 605-620 (2015)
Stem Cell Reports, Vol 4, Iss 4, Pp 605-620 (2015)
Summary Human embryonic stem cell (hESC)-derived pancreatic progenitor cells effectively reverse hyperglycemia in rodent models of type 1 diabetes, but their capacity to treat type 2 diabetes has not been reported. An immunodeficient model of type 2
Autor:
Timothy J. Kieffer, Majid Mojibian, Nelly Saber, Shannon O'Dwyer, Jessica K. Fox, Jennifer E. Bruin, Alireza Rezania, Payal Arora
Publikováno v:
Diabetes. 65(5)
Pancreatic progenitors derived from human embryonic stem cells (hESCs) are a potential source of transplantable cells for treating diabetes and are currently being tested in clinical trials. Yet, how the milieu of pancreatic progenitor cells, includi
Autor:
Shannon O'Dwyer, Alireza Rezania, Campbell Drohan, Timothy J. Kieffer, Jennifer E. Bruin, Nelly Saber
Publikováno v:
Canadian Journal of Diabetes. 40:S13-S14
Publikováno v:
The FASEB Journal. 27