Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nelly Oliver"'
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
MAF file for copy number variations identified in the cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50ef08101f64b6034b9a8359c272e7a
https://doi.org/10.1158/2159-8290.22532632
https://doi.org/10.1158/2159-8290.22532632
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
Treatment history for patients enrolled on the PancSeq protocol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b56a4b2885a7dd9c5ac333c18bd8e4
https://doi.org/10.1158/2159-8290.22532611
https://doi.org/10.1158/2159-8290.22532611
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
Supplementary Figure S1: Overview of workflow and data generation. Supplementary Figure S2: Analysis of neoplastic cellularity. Supplementary Figure S3: Recurrent copy number alterations. Supplementary Figure S4: Mutational signature analysis. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35721db75fe856f18b8b1d93e935fda4
https://doi.org/10.1158/2159-8290.22532623.v1
https://doi.org/10.1158/2159-8290.22532623.v1
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
Supplementary Experimental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673f1a20eafeed91edfea9b46bf44a50
https://doi.org/10.1158/2159-8290.22532626.v1
https://doi.org/10.1158/2159-8290.22532626.v1
Autor:
Brian M. Wolpin, Scott L. Carter, Ryan B. Corcoran, William C. Hahn, Jen Jen Yeh, Nikhil Wagle, David A. Tuveson, Paul B. Shyn, Jeffrey W. Miller, Robert J. Mayer, Matthew H. Kulke, Bruce E. Johnson, Jason L. Hornick, Gad Getz, Levi A. Garraway, Charles S. Fuchs, Matthew B. Yurgelun, Dean J. Welsch, Deborah Knoerzer, Richard B. Lanman, Rebecca J. Nagy, Stuart G. Silverman, Ewa Sicinska, Geoffrey I. Shapiro, Marvin Ryou, Douglas A. Rubinson, Michael H. Rosenthal, Kimberly Perez, Anuj K. Patel, Kimmie Ng, Janet E. Murphy, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kunal Jajoo, Leona A. Doyle, James M. Cleary, Thomas Clancy, Kelly P. Burke, Joseph P. St. Pierre, Heather A. Shahzade, Emily E. Van Seventer, Brandon Nadres, Annacarolina Da Silva, Ana Babic, Nelly Oliver, Karla Helvie, Kristin Anderka, Lori Marini, Devin McCabe, Emma Reilly, Marisa W. Welch, Dorisanne Ragon, Lauren K. Brais, Jaegil Kim, Srivatsan Raghavan, Mehlika Hazar-Rethinam, Arezou A. Ghazani, Richard A. Moffitt, Nicholas D. Camarda, Jonathan A. Nowak, Andrew J. Aguirre
MAF file for mutations identified in the cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f60efb41831b325353f91022fa1d5de
https://doi.org/10.1158/2159-8290.22532629.v1
https://doi.org/10.1158/2159-8290.22532629.v1
Autor:
Karla Helvie, Laura DelloStritto, Lori Marini, Nelly Oliver, Miraj Patel, Sébastien Vigneau, Nikhil Wagle, Asaf Rotem, Bruce Johnson
This standard operating procedure was established by the Center for Cancer Genomics at Dana-Farber Cancer Institute, the Brigham and Women's Hospital and the Klarman Cell Observatory at the Broad Institute, to standardize the collection of fresh meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc6c857190cdf5e6ad1951939116cdb
https://doi.org/10.17504/protocols.io.b2faqbie
https://doi.org/10.17504/protocols.io.b2faqbie
Autor:
Samuel S. Freeman, Ofir Cohen, Eric P. Winer, Nicole S. Persky, Lori Marini, Adrienne G. Waks, Nelly Oliver, Seth A. Wander, Aviv Regev, Michael S. Cuoco, Utthara Nayar, Nikhil Wagle, Corrie A. Painter, Christian Kapstad, Orit Rozenblatt-Rosen, Karla Helvie, Cynthia X. Ma, Nan Lin
Publikováno v:
Prof. Regev via Courtney Crummett
Seventy percent of breast cancers express the estrogen receptor (ER), and agents that target the ER are the mainstay of treatment. However, virtually all people with ER+ breast cancer develop resistance to ER-directed agents in the metastatic setting
Autor:
Emily E. Van Seventer, Ana Babic, Jeffrey W. Miller, Deborah Knoerzer, Marvin Ryou, Heather A. Shahzade, Nadine Jackson McCleary, Jaegil Kim, Douglas A. Rubinson, Mehlika Hazar-Rethinam, Rebecca J. Nagy, Kristin Anderka, David A. Tuveson, Robert J. Mayer, Scott L. Carter, Leona A. Doyle, Nelly Oliver, Nicholas D. Camarda, Kimmie Ng, Matthew B. Yurgelun, Lauren K. Brais, Levi A. Garraway, Jeffrey A. Meyerhardt, Arezou A. Ghazani, Richard A. Moffitt, Stuart G. Silverman, Thomas E. Clancy, Srivatsan Raghavan, Annacarolina da Silva, Brandon Nadres, James M. Cleary, Andrew J. Aguirre, Kunal Jajoo, Kelly P. Burke, Michael H. Rosenthal, Emma Reilly, Kimberly Perez, Jonathan A. Nowak, Charles S. Fuchs, Dean Welsch, Jen Jen Yeh, Matthew H. Kulke, Marisa W. Welch, William C. Hahn, Anuj K. Patel, Ryan B. Corcoran, Karla Helvie, Paul B. Shyn, Gad Getz, Nikhil Wagle, Dorisanne Y. Ragon, Lori Marini, Geoffrey I. Shapiro, Janet E. Murphy, Brian M. Wolpin, Richard B. Lanman, Devin McCabe, Jason L. Hornick, Bruce E. Johnson, Ewa Sicinska, Joseph P. St. Pierre
Publikováno v:
Cancer Discovery. 8:1096-1111
Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but molecular characterization is not yet standard in clinical care. We implemented a biopsy protocol to perform time-sensitive whole-exome sequencing and RNA sequencing
Autor:
Ruth Lederman, Eliezer M. Van Allen, Stacy W. Gray, Nelly Oliver, Aaron Suarez, Anna Revette, Angel M. Cronin, Lynette M. Sholl, Jordan Bryan, Ethan Cerami, Charlotte E. Lee, Jeffrey Gagan, Carol Lowenstein, Hajime Uno
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA
Objective Misinterpretation of complex genomic data presents a major challenge in the implementation of precision oncology. We sought to determine whether interactive genomic reports with embedded clinician education and optimized data visualization
Autor:
Zhenwei Zhang, Laura Polacek, Sara M. Tolaney, Joshua M. Francis, Samuel S. Freeman, Paz Polak, Rachel Leeson, J. Christopher Love, Huiming Ding, Sairah Mahmud, Nelly Oliver, Rachel M. Barry, Atish D. Choudhury, Levi A. Garraway, Gregory Gydush, Andrea Saltzman, Eliezer M. Van Allen, Coyin Oh, Viktor A. Adalsteinsson, Justin Rhoades, Jesse S. Boehm, Sarah C. Reed, Seong Ho Jeong, Todd R. Golub, Karla Helvie, Matthew Meyerson, Lauren C. Harshman, Gad Getz, Ignaty Leshchiner, Jens G. Lohr, Chip Stewart, Heather A. Parsons, Jaegil Kim, Adrienne G. Waks, Mari Nakabayashi, Lori Marini, Mara Rosenberg, Edward P. O’Connor, Daniel Rosebrock, Denis Loginov, Daniel G. Stover, Rebecca A. Santiago, Nikhil Wagle, Joseph F. Kramkowski, Mary-Ellen Taplin, Eric P. Winer, Nan Lin, Ofir Cohen, Cheng-Zhong Zhang, Dimitri Livitz, Emily Lipscomb, Gavin Ha, Molly Schleicher, Denisse Rotem, Max Lloyd, Margaret S. Merrill, Cory M. Johannessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Whole-exome sequencing of cell-free DNA (cfDNA) could enable comprehensive profiling of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies is uncertain. Here we report ichorCNA, software that quantifies tumor content i