Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Nelly M. Cruz"'
Autor:
Sienna R. Li, Ramila E. Gulieva, Louisa Helms, Nelly M. Cruz, Thomas Vincent, Hongxia Fu, Jonathan Himmelfarb, Benjamin S. Freedman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In polycystic kidney disease (PKD), fluid-filled cysts arise from tubules. Here the authors show that subjecting organoids to fluid shear stress in a PKD-on-a-chip microphysiological system promotes cyst expansion via an absorptive pathway.
Externí odkaz:
https://doaj.org/article/c46ae4379a784182858157d336548bc7
Autor:
Janani Gopalan, Mitchell H Omar, Ankita Roy, Nelly M Cruz, Jerome Falcone, Kiana N Jones, Katherine A Forbush, Jonathan Himmelfarb, Benjamin S Freedman, John D Scott
Publikováno v:
eLife, Vol 10 (2021)
Pathophysiological defects in water homeostasis can lead to renal failure. Likewise, common genetic disorders associated with abnormal cytoskeletal dynamics in the kidney collecting ducts and perturbed calcium and cAMP signaling in the ciliary compar
Externí odkaz:
https://doaj.org/article/8e27976a6db44296b8fc0b9c29cb8ab4
Autor:
Shruthy Suresh, Roy Rabbie, Manik Garg, Dianne Lumaquin, Ting-Hsiang Huang, Emily Montal, Yilun Ma, Nelly M Cruz, Xinran Tang, Jérémie Nsengimana, Julia Newton-Bishop, Miranda V. Hunter, Yuxin Zhu, Kevin Chen, Elisa de Stanchina, David J. Adams, Richard M. White
Publikováno v:
Cancer Discovery. 13:194-215
In melanoma, predicting which tumors will ultimately metastasize guides treatment decisions. Transcriptional signatures of primary tumors have been utilized to predict metastasis, but which among these are driver or passenger events remains unclear.
Autor:
Richard M. White, David J. Adams, Elisa de Stanchina, Kevin Chen, Yuxin Zhu, Miranda V. Hunter, Julia Newton-Bishop, Jérémie Nsengimana, Xinran Tang, Nelly M Cruz, Yilun Ma, Emily Montal, Ting-Hsiang Huang, Dianne Lumaquin, Manik Garg, Roy Rabbie, Shruthy Suresh
CRISPR Sequencing of MAS2X tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bbb2109dfc47059a633fc565a22002
https://doi.org/10.1158/2159-8290.22541845
https://doi.org/10.1158/2159-8290.22541845
Autor:
Richard M. White, David J. Adams, Elisa de Stanchina, Kevin Chen, Yuxin Zhu, Miranda V. Hunter, Julia Newton-Bishop, Jérémie Nsengimana, Xinran Tang, Nelly M Cruz, Yilun Ma, Emily Montal, Ting-Hsiang Huang, Dianne Lumaquin, Manik Garg, Roy Rabbie, Shruthy Suresh
Supplementary Table S2. David GO analysis of AVAST-M signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0e9799c03ebb362eef081dded544b4
https://doi.org/10.1158/2159-8290.22541866.v1
https://doi.org/10.1158/2159-8290.22541866.v1
Autor:
Richard M. White, David J. Adams, Elisa de Stanchina, Kevin Chen, Yuxin Zhu, Miranda V. Hunter, Julia Newton-Bishop, Jérémie Nsengimana, Xinran Tang, Nelly M Cruz, Yilun Ma, Emily Montal, Ting-Hsiang Huang, Dianne Lumaquin, Manik Garg, Roy Rabbie, Shruthy Suresh
In melanoma, predicting which tumors will ultimately metastasize guides treatment decisions. Transcriptional signatures of primary tumors have been utilized to predict metastasis, but which among these are driver or passenger events remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5967f7603da8c50df3c3df95c6817ddf
https://doi.org/10.1158/2159-8290.c.6549751
https://doi.org/10.1158/2159-8290.c.6549751
Autor:
Joshua M. Weiss, Miranda V. Hunter, Nelly M. Cruz, Arianna Baggiolini, Mohita Tagore, Yilun Ma, Sandra Misale, Michelangelo Marasco, Theresa Simon-Vermot, Nathaniel R. Campbell, Felicity Newell, James S. Wilmott, Peter A. Johansson, John F. Thompson, Georgina V. Long, John V. Pearson, Graham J. Mann, Richard A. Scolyer, Nicola Waddell, Emily D. Montal, Ting-Hsiang Huang, Philip Jonsson, Mark T.A. Donoghue, Christopher C. Harris, Barry S. Taylor, Tianhao Xu, Ronan Chaligné, Pavel V. Shliaha, Ronald Hendrickson, Achim A. Jungbluth, Cecilia Lezcano, Richard Koche, Lorenz Studer, Charlotte E. Ariyan, David B. Solit, Jedd D. Wolchok, Taha Merghoub, Neal Rosen, Nicholas K. Hayward, Richard M. White
Publikováno v:
Weiss, J M, Hunter, M V, Cruz, N M, Baggiolini, A, Tagore, M, Ma, Y, Misale, S, Marasco, M, Simon-Vermot, T, Campbell, N R, Newell, F, Wilmott, J S, Johansson, P A, Thompson, J F, Long, G V, Pearson, J V, Mann, G J, Scolyer, R A, Waddell, N, Montal, E D, Huang, T H, Jonsson, P, Donoghue, M T A, Harris, C C, Taylor, B S, Xu, T, Chaligné, R, Shliaha, P V, Hendrickson, R, Jungbluth, A A, Lezcano, C, Koche, R, Studer, L, Ariyan, C E, Solit, D B, Wolchok, J D, Merghoub, T, Rosen, N, Hayward, N K & White, R M 2022, ' Anatomic position determines oncogenic specificity in melanoma ', Nature, vol. 604, pp. 354-361 . https://doi.org/10.1038/s41586-022-04584-6
Nature
Nature
Oncogenic alterations to DNA are not transforming in all cellular contexts1,2. This may be due to pre-existing transcriptional programmes in the cell of origin. Here we define anatomic position as a major determinant of why cells respond to specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b39395de5cccb872bc76acd0f99b36d
https://portal.findresearcher.sdu.dk/da/publications/fc93f265-733a-47a2-81d0-e175a3bb1f60
https://portal.findresearcher.sdu.dk/da/publications/fc93f265-733a-47a2-81d0-e175a3bb1f60
Autor:
Yujie Fan, James Hackland, Arianna Baggiolini, Lin Y. Hung, Huiyong Zhao, Paul Zumbo, Polina Oberst, Andrew P. Minotti, Emiliano Hergenreder, Sarah Najjar, Zixing Huang, Nelly M. Cruz, Aaron Zhong, Mega Sidharta, Ting Zhou, Elisa de Stanchina, Doron Betel, Richard M. White, Michael Gershon, Kara Gross Margolis, Lorenz Studer
Publikováno v:
Cell Stem Cell. 30:264-282.e9
Autor:
Jerome Falcone, Nelly M. Cruz, Janani Gopalan, Benjamin S. Freedman, Katherine A. Forbush, Kiana N Jones, John D. Scott, Jonathan Himmelfarb, Ankita Roy, Mitchell H Omar
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Pathophysiological defects in water homeostasis can lead to renal failure. Likewise, common genetic disorders associated with abnormal cytoskeletal dynamics in the kidney collecting ducts and perturbed calcium and cAMP signaling in the ciliary compar
Autor:
Mitchell H Omar, Jerome Falcone, Nelly M. Cruz, Katherine A. Forbush, Kiana N Jones, Benjamin S. Freedman, Ankita Roy, Jonathan Himmelfarb, John D. Scott, Janani Gopalan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1826b1994f6ff4d3090c754994496a7
https://doi.org/10.7554/elife.67828.sa2
https://doi.org/10.7554/elife.67828.sa2