Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nelly Fransén"'
Publikováno v:
Pharmaceutical Research. 26:1618-1625
To create improved pharmaceutical formulations for nasal and sublingual administration of desmopressin and investigate their pharmacokinetic profiles in comparison with a commercial nasal liquid spray and finally to evaluate the volunteers' opinions
Publikováno v:
Particle & Particle Systems Characterization. 25:397-405
In interactive mixtures with small carrier particles, the content variability is often higher than predicted by available models despite the significant degree of interaction visualized with Scanning Electron Microscopy (SEM). The present work detail
Publikováno v:
Journal of Pharmaceutical Sciences. 97:3855-3864
The residence time in the nasal cavity can be prolonged by dry particles that absorb water and subsequently increase the viscosity of the mucus layer. A novel nasal drug delivery system based on interactive mixtures has previously been developed, whe
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 67:370-376
The aim of this study was to investigate whether mucoadhesive interactive mixtures can be created using carrier particles in a size range appropriate for nasal administration, i.e. 10-50 microm. We also used theoretical models to investigate if homog
Publikováno v:
Journal of Drug Delivery Science and Technology. 17:267-271
The objective was to investigate the transport of dihydroergotamine (DHE) across porcine nasal respiratory and olfactory mucosa and to evaluate the absorption enhancing effect of a novel dry pow ...
Publikováno v:
The Journal of pharmacy and pharmacology. 60(12)
We have evaluated the interactions between superdisintegrants and drugs with different physicochemical characteristics, which may affect the in-vivo absorption e.g. after mucosal administration. The binding of sodium salicylate, naproxen, methyl hydr
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 59(3)
The nasal uptake of a 3000 Da fluorescein dextran (FD3) was investigated in rats, using fluorescence microscopy. The uptake from a formulation containing deacetylated gellan gum, an in situ gelling agent, was compared to that from a mannitol solution