Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nelly E. Villacreses"'
Autor:
Thad A. Rosenberger, Nelly E. Villacreses, Miguel A. Contreras, Joseph V. Bonventre, Stanley I. Rapoport
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 109-117 (2003)
We examined brain phospholipid metabolism in mice in which the cytosolic phospholipase A2 (cPLA2, Type IV, 85 k11111111111111111135) was knocked out (cPLA2−/− mice). Compared with controls, these mice demonstrated altered brain concentrations of
Externí odkaz:
https://doaj.org/article/769798e5771c4aaa8eda5b64b0fedb80
Publikováno v:
Neurochemistry International. 56:501-507
In a rat model of neuroinflammation, produced by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide (LPS), we reported that the brain concentrations of non-esterified brain arachidonic acid (AA, 20:4 n-6) and its eicosanoid pr
Publikováno v:
Biological Psychiatry. 62:934-943
Background Lithium and carbamazepine (CBZ) are used to treat mania in bipolar disorder. When given chronically to rats, both agents reduce arachidonic acid (AA) turnover in brain phospholipids and downstream AA metabolism. Lithium in rats also attenu
Publikováno v:
Neurochemical Research. 32:1857-1867
Cholinergic muscarinic receptors, when stimulated by arecoline, can activate cytosolic phospholipase A(2) (cPLA(2)) to release arachidonic acid (AA) from membrane phospholipid. This signal can be imaged in the brain in vivo using quantitative autorad
Publikováno v:
Journal of Neurochemistry. 102:761-772
Neuroinflammation, caused by a 6-day intracerebroventricular infusion of lipopolysaccharide (LPS) in rats, is associated with the up-regulation of brain arachidonic acid (AA) metabolism markers. Because chronic LiCl down-regulates markers of brain AA
Publikováno v:
Psychopharmacology. 180:12-20
The serotonin reuptake transporter (SERT) helps to regulate brain serotonergic transmission and is the target of some antidepressants. To further understand SERT function, we measured a marker of regional brain phospholipase A2 (PLA2) activation in S
Publikováno v:
Journal of neurochemistry. 102(3)
Neuroinflammation, caused by a 6-day intracerebroventricular infusion of lipopolysaccharide (LPS) in rats, is associated with the up-regulation of brain arachidonic acid (AA) metabolism markers. Because chronic LiCl down-regulates markers of brain AA
Autor:
H. Umesha Shetty, Kaizong Ma, Stanley I. Rapoport, Nelly E. Villacreses, Thad A. Rosenberger, Joseph Deutsch
Publikováno v:
Neurochemical research. 31(6)
The in vivo rate of turnover of phosphatidylinositol (PtdIns) in brain is not known. In brain, certain receptor-mediated signal transduction involves metabolism of PtdIns and a method to measure its turnover in awake animals is useful in studying the
Autor:
Stanley I. Rapoport, Mireille Basselin, Kaizong Ma, Jane M. Bell, Robert Langenbach, Nelly E. Villacreses
Publikováno v:
Journal of neurochemistry. 96(3)
Studies were performed to determine if cyclooxygenase (COX)-2 regulates muscarinic receptor-initiated signaling involving brain phospholipase A2 (PLA2) activation and arachidonic acid (AA; 20 : 4n-6) release. AA incorporation coefficients, k* (brain
Publikováno v:
Journal of neurochemistry. 91(4)
In a rat model of neuroinflammation produced by an intracerebral ventricular infusion of bacterial lipopolysaccaride (LPS), we measured the coefficients of incorporation (k*) of arachidonic acid (AA, 20 : 4n-6) from plasma into each of 80 brain regio