Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nelly, Leung"'
Autor:
Ina-Kristin Behrens, Benjamin Busch, Hellen Ishikawa-Ankerhold, Pia Palamides, John E. Shively, Cliff Stanners, Carlos Chan, Nelly Leung, Scott Gray-Owen, Rainer Haas
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT The cag type IV secretion system (cag-T4SS) of Helicobacter pylori exploits specific cellular carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), such as CEACAM1, -3, -5, and -6, as cellular receptors for CagA translocation i
Externí odkaz:
https://doaj.org/article/ddb179f2f9174e459c0be8f3bc5d3a80
Autor:
Xin Fang, Jonathan M. Monk, Sergey Nurk, Margarita Akseshina, Qiyun Zhu, Christopher Gemmell, Connor Gianetto-Hill, Nelly Leung, Richard Szubin, Jon Sanders, Paul L. Beck, Weizhong Li, William J. Sandborn, Scott D. Gray-Owen, Rob Knight, Emma Allen-Vercoe, Bernhard O. Palsson, Larry Smarr
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Dysbiosis of the gut microbiome, including elevated abundance of putative leading bacterial triggers such as E. coli in inflammatory bowel disease (IBD) patients, is of great interest. To date, most E. coli studies in IBD patients are focused on clin
Externí odkaz:
https://doaj.org/article/294c664d1df0498c8b6be813cca84d23
Autor:
Pia Palamides, John E. Shively, Rainer Haas, Carlos H. F. Chan, Hellen Ishikawa-Ankerhold, Ina‐Kristin Behrens, Benjamin Busch, Cliff Stanners, Scott D. Gray-Owen, Nelly Leung
Publikováno v:
mBio, Vol 11, Iss 1, p e03256-19 (2020)
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1 (2020)
The cag type IV secretion system (cag-T4SS) of Helicobacter pylori exploits specific cellular carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), such as CEACAM1, -3, -5, and -6, as cellular receptors for CagA translocation into human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eabd0610ec20df1b1194003fe353eb2
https://doaj.org/article/01b14fca672a45a6acd86fcd17de1689
https://doaj.org/article/01b14fca672a45a6acd86fcd17de1689
Autor:
Varun C. Anipindi, Ian P. Francis, Anna Sintsova, Yazdan Shaik-Dasthagirisaheb, Stacey X. Xu, Epshita A. Islam, Lee M. Wetzler, Nelly Leung, Charu Kaushic, Mohsen Amin, Scott D. Gray-Owen
The gonococcal Opa proteins are an antigenically variable family of surface adhesins that bind human carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), CEACAM3, CEACAM5, and/or CEACAM6, cell surface glycoproteins that are differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a1a13e0393949ff1bd16d845653a93
https://europepmc.org/articles/PMC6056862/
https://europepmc.org/articles/PMC6056862/
Autor:
Jianjun Li, Carolyn M. Buckwalter, Anna Sintsova, Jason Moffat, Nelly Leung, Alan Cochrane, Ryan G. Gaudet, Scott D. Gray-Owen, Andrew D. Cox
Publikováno v:
Science. 348:1251-1255
Detecting Gramnegative bacteria Invariant molecules specific to different classes of microbes, but not expressed by eukaryotic cells, alert the immune system to a potential invader. Gaudet et al. identified one such molecule expressed by a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab7f9b2e9f0ee2cffa43ac09d6d8469
https://doi.org/10.1126/science.aaa4921
https://doi.org/10.1126/science.aaa4921
Publikováno v:
Infection and Immunity. 81:1334-1340
The bacterial pathogen Listeria monocytogenes causes serious food-borne illnesses in pregnant women and the immunocompromised. L. monocytogenes promotes its internalization into host epithelial cells and then uses an F-actin-dependent motility proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c6b1595d633f3dbe7087b91bcd79c7
https://doi.org/10.1128/iai.01377-12
https://doi.org/10.1128/iai.01377-12
Publikováno v:
Cellular Microbiology. 15:446-457
Adherent-invasive Escherichia coli (AIEC) is a pathogen isolated from the ileum of patients with Crohn disease. IFNγ is a key mediator of immunity, which regulates inflammatory responses to microbial infections. Previously, we showed enterohemorrhag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3bf7581da379370cdd00a19a16da1c0
https://doi.org/10.1111/cmi.12048
https://doi.org/10.1111/cmi.12048
Autor:
Ryan G, Gaudet, Anna, Sintsova, Carolyn M, Buckwalter, Nelly, Leung, Alan, Cochrane, Jianjun, Li, Andrew D, Cox, Jason, Moffat, Scott D, Gray-Owen
Publikováno v:
Science (New York, N.Y.). 348(6240)
Host recognition of pathogen-associated molecular patterns (PAMPs) initiates an innate immune response that is critical for pathogen elimination and engagement of adaptive immunity. Here we show that mammalian cells can detect and respond to the bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f29f0eb3b32a6ebf18b98f6cd7abf45
https://pubmed.ncbi.nlm.nih.gov/26109127
https://pubmed.ncbi.nlm.nih.gov/26109127
Publikováno v:
Oncogene. 25:5527-5536
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein that is part of the carcinoembryonic antigen and the immunoglobulin superfamilies. We have shown that it functions as a tumor suppressor and that this function depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ea85415c91a6eff8640ec9ccb70d60
https://doi.org/10.1038/sj.onc.1209541
https://doi.org/10.1038/sj.onc.1209541
Publikováno v:
Journal of Biological Chemistry. 278:16929-16935
The CEACAM1 cell adhesion molecule is a member of the carcinoembryonic antigen family. In the mouse, four distinct isoforms are generated by alternative splicing. These encode either two or four immunoglobulin domains linked through a transmembrane d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3561ade8699cbe1cc6af9535f3505e9f
https://doi.org/10.1074/jbc.m301842200
https://doi.org/10.1074/jbc.m301842200