Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nelly, Arroyo"'
Autor:
Angel Núñez-Marrero, Lenin Godoy, Julie Dutil, Nelly Arroyo, Mohammad Zillur Rahman, Jaime Matta
Publikováno v:
Oncotarget
Interleukin-12 (IL-12) is a proinflammatory cytokine that links innate and adaptive immune responses against tumor cells. Single Nucleotide Polymorphisms (SNPs) in IL-12 genes have been associated with cancer risk. However, limited studies have asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c237e27ef8e2fad185c56fa597087
http://europepmc.org/articles/PMC7500104
http://europepmc.org/articles/PMC7500104
Autor:
Rafael Rivera-Lugo, Miguel Echenique, Lenin Godoy, Elinette Albino, Luis Negrón, Julie Dutil, Alvaro N.A. Monteiro, Jaime Matta, Nelly Arroyo
Publikováno v:
Genetic Testing and Molecular Biomarkers. 22:85-89
The role of deep intronic variants in hereditary cancer susceptibility has been largely understudied. Previously, the BRCA2 c.6937 + 594TG variant has been shown to preferentially promote the inclusion of a 95 nucleotide cryptic exon and to introduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44718cfec49922b76cbc29b275063f3
https://doi.org/10.1089/gtmb.2017.0187
https://doi.org/10.1089/gtmb.2017.0187
Autor:
Jamie K. Teer, Sean Yoder, Julie Dutil, Wei Lue Tong, Miguel Echenique, Rachid Karam, Alvaro N.A. Monteiro, Volha A. Golubeva, Jaime Matta, Nelly Arroyo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Inherited pathogenic variants in genes that confer moderate to high risk of breast cancer may explain up to 50% of familial breast cancer. This study aimed at identifying inherited pathogenic variants in breast cancer cases from Puerto Rico that were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff25ac30e83ca9d0ab9f7585421c82f8
https://pubmed.ncbi.nlm.nih.gov/31780696
https://pubmed.ncbi.nlm.nih.gov/31780696
Autor:
Hector J, Diaz-Zabala, Ana P, Ortiz, Lisa, Garland, Kristine, Jones, Cynthia M, Perez, Edna, Mora, Nelly, Arroyo, Taras K, Oleksyk, Miguel, Echenique, Jaime L, Matta, Michael, Dean, Julie, Dutil
Publikováno v:
Cancers
Breast cancer is the most common cause of cancer diagnosis in women and is responsible for considerable mortality among the women of Puerto Rico. However, there are few studies in Puerto Rico on the genetic factors influencing risk. To determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39ae59579a047071f3470dc8b7aac829
https://pubmed.ncbi.nlm.nih.gov/30400234
https://pubmed.ncbi.nlm.nih.gov/30400234
Autor:
Hector J. Diaz-Zabala, Lisa Garland, Cynthia M. Pérez, Michael Dean, Edna M. Mora, Miguel Echenique, Nelly Arroyo, Julie Dutil, Jaime Matta, Ana P. Ortiz, Kristine Jones, Taras K. Oleksyk
Publikováno v:
Cancers
Volume 10
Issue 11
Cancers, Vol 10, Iss 11, p 419 (2018)
Volume 10
Issue 11
Cancers, Vol 10, Iss 11, p 419 (2018)
Breast cancer is the most common cause of cancer diagnosis in women and is responsible for considerable mortality among the women of Puerto Rico. However, there are few studies in Puerto Rico on the genetic factors influencing risk. To determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b2dec5b990cc765d24feabb1ea903e
https://doi.org/10.3390/cancers10110419
https://doi.org/10.3390/cancers10110419
Publikováno v:
Free Radical Biology and Medicine. 36:1542-1554
Recent studies have demonstrated that H2O2 acts as a second messenger of mitogenic signaling and that catalase is under the regulation of PKA and PKC signaling. Here we examined whether catalase binds any mitogenic signaling molecules. Our results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89e3a896242ae756fcb7807ce042fa4
https://doi.org/10.1016/j.freeradbiomed.2004.04.006
https://doi.org/10.1016/j.freeradbiomed.2004.04.006
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::005a5dc454b54b3b9d0e8d1ce05f5380
https://doi.org/10.1096/fasebj.27.1_supplement.lb91
https://doi.org/10.1096/fasebj.27.1_supplement.lb91
Publikováno v:
The Journal of Immunology. 194:187.7-187.7
Interleukin-12 (IL-12) is a dimeric cytokine which has demonstrated anti-cancer effects in vitro and in vivo. However, the role of this cytokine in breast cancer (BC) has not been studied thoroughly. In this pilot study, the levels of the IL-12 p70 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5825b6fa2653eb1f60c42121b16ca9ec
https://doi.org/10.4049/jimmunol.194.supp.187.7
https://doi.org/10.4049/jimmunol.194.supp.187.7
Publikováno v:
FEBS Letters. (3):327-332
Here, we examined whether catalase binds SHP2 and alters SHP2 susceptibility to H2O2. Our results indicated that serum and fibrinogen commonly evoked catalase binding to SHP2 in HeLa and A549 cells in a herbimycin-A and TNFα sensitive manner. Expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5241d25020adadc1f4cc73e48b948a22