Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nellwyn Hagan"'
Autor:
Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chretien, Michael LaMorte, Timothy R. Hammond, Agnes Cheong, Sean K. Ryan, Andrew Macklin, Mindy Zhang, Nilesh Pande, Evis Havari, Timothy J. Turner, Anthony Chomyk, Emilie Christie, Bruce D. Trapp, Dimitry Ofengeim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neuroinflammation in the central nervous system (CNS), driven largely by resident phagocytes, has been proposed as a significant contributor to disability accumulation in multiple sclerosis (MS) but has not been addressed therapeutically. Br
Externí odkaz:
https://doaj.org/article/7240258f9fe44a898fcf295ec6f91164
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
The cerebellum (Cb) is an exquisite structure that controls elaborate motor behaviors and is essential for sensory-motor learning. During development, the Cb is derived from rhombomere 1 (r1). Within this embryonic compartment, precursors in r1 are p
Externí odkaz:
https://doaj.org/article/fc81cde9450842ce95207107ca484302
Autor:
Maria V Gelfand, Nellwyn Hagan, Aleksandra Tata, Won-Jong Oh, Baptiste Lacoste, Kyu-Tae Kang, Justyna Kopycinska, Joyce Bischoff, Jia-Huai Wang, Chenghua Gu
Publikováno v:
eLife, Vol 3 (2014)
During development, tissue repair, and tumor growth, most blood vessel networks are generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key regulator of this process and currently both VEGF and its receptors, VEGFR1, VEGFR2
Externí odkaz:
https://doaj.org/article/3612d88f088b464b8112d62e3eb5797c
Autor:
Lisa Woodworth, Mario Kreutzfeldt, Ingrid Wagner, Fred Wolf, Nellwyn Hagan, Tradite Neziraj, Dimitry Ofengeim, Tanja Jürgens, Joseph Gans, Emily M. Ullrich Gavilanes, Nicolas Snaidero, Thomas Misgeld, Eduardo Beltrán, Juan Daniel Flórez Weidinger, Mehrnoosh Jafari, Adrian-Minh Schumacher, Virág Kocsis-Jutka, Martin Kerschensteiner, Daniel Engels, Ruben Portugues, Doron Merkler, Stephanie S. Schmidt
Publikováno v:
Nature Neuroscience
Nature Neuroscience (2021)
Nature neuroscience 24(3), 355-367 (2021). doi:10.1038/s41593-020-00780-7
Nature Neuroscience (2021)
Nature neuroscience 24(3), 355-367 (2021). doi:10.1038/s41593-020-00780-7
Cortical pathology contributes to chronic cognitive impairment of patients suffering from the neuroinflammatory disease multiple sclerosis (MS). How such gray matter inflammation affects neuronal structure and function is not well understood. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebcdb3392cdcf8bf64de6471ae63665
Autor:
Matija Zelic, Jose Sancho, Yi Li, Nellwyn Hagan, Oleg Butovsky, John L. Kane, Lisa Woodworth, Andrew Scholte, Charlotte Madore, Michael Kothe, Barbara Gisevius, Dimitry Ofengeim, Jacqueline Saleh, Jonathan Proto, Deepak Grover, Maria Fitzgerald, Aiden Haghikia, Jinyu Liu, Amy Mahan
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-25 (2020)
Cell Death and Disease, Vol 11, Iss 10, Pp 1-25 (2020)
Microglia serve as the innate immune cells of the central nervous system (CNS) by providing continuous surveillance of the CNS microenvironment and initiating defense mechanisms to protect CNS tissue. Upon injury, microglia transition into an activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc9ca138cd4d331e3ff620100313d25
http://europepmc.org/articles/PMC7584629
http://europepmc.org/articles/PMC7584629
Autor:
Dimitry Ofengeim, Fred Wolf, Emily M. Ullrich Gavilanes, Nicolas Snaidero, Tradite Neziraj, Nellwyn Hagan, Thomas Misgeld, Lisa Woodworth, Eduardo Beltrán, Juan Daniel Flórez Weidinger, Joseph Gans, Ruben Portugues, Adrian-Minh Schumacher, Mehrnoosh Jafari, Martin Kerschensteiner, Stephanie S. Schmidt, Tanja Jürgens, Doron Merkler, Mario Kreutzfeldt
SUMMARYCortical pathology contributes to chronic cognitive impairment of patients suffering from the neuroinflammatory disease multiple sclerosis (MS). How such gray matter inflammation affects neuronal structure and function is not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a0d61e55c15ba450d643f7c621a0a6
https://doi.org/10.1101/758193
https://doi.org/10.1101/758193
Publikováno v:
Journal of Neuroscience. 34:8557-8569
The motor and learning functions of the striatum are critically dependent on synaptic transmission from midbrain dopamine neurons and striatal cholinergic interneurons (CINs). Both neural populations alter their discharge in vivo in response to salie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456afc907413f2ee6964b9d6a6e22d58
https://doi.org/10.1523/jneurosci.0589-14.2014
https://doi.org/10.1523/jneurosci.0589-14.2014
Autor:
Mark Zervas, Nellwyn Hagan
Publikováno v:
Molecular and Cellular Neuroscience. 49:217-229
The cerebellum (Cb) controls movement related physiology using a diverse array of morphologically and biochemically distinct neurons. During development, the Cb is derived from rhombomere 1 (r1), an embryonic compartment patterned by a signaling cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7201883d8ddbc6dba58e82bc11d6b9
https://doi.org/10.1016/j.mcn.2011.11.008
https://doi.org/10.1016/j.mcn.2011.11.008
Publikováno v:
Gene Expression Patterns. 9:475-489
A long-standing problem in development is understanding how progenitor cells transiently expressing genes contribute to complex anatomical and functional structures. In the developing nervous system an additional level of complexity arises when consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6aa65daa4f99330e93224365661d606
https://doi.org/10.1016/j.gep.2009.07.007
https://doi.org/10.1016/j.gep.2009.07.007
Autor:
Nellwyn Hagan, Jia-Huai Wang, Chenghua Gu, Joyce Bischoff, Baptiste Lacoste, Justyna Kopycinska, Maria V Gelfand, Kyu-Tae Kang, Won-Jong Oh, Aleksandra Tata
Publikováno v:
eLife, Vol 3 (2014)
eLife
eLife
During development, tissue repair, and tumor growth, most blood vessel networks are generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key regulator of this process and currently both VEGF and its receptors, VEGFR1, VEGFR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f88c3da8a02b493dd9700ac3e407913
https://doi.org/10.7554/elife.03720
https://doi.org/10.7554/elife.03720