Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nelli, Wolf"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28546 (2011)
Peripheral T cell lymphomas (PTCLs) are associated with a poor prognosis due to often advanced disease at the time of diagnosis and due to a lack of efficient therapeutic options. Therefore, appropriate animal models of PTCL are vital to improve clin
Externí odkaz:
https://doaj.org/article/e5e46d6df5ef4b49ba44dc5d285b9ea6
Publikováno v:
European Journal of Immunology. 45:1997-2007
Upon transplantation of T cells from a CD28 superagonist (CD28-SA) treated donor into an irradiated allogeneic host, the CD28-SA-induced activation and expansion of Treg cells inhibits acute graft versus host disease (aGvHD), while not abrogating the
Autor:
Helga Rübsamen-Schaeff, Andreas Weishaupt, Daniela Paulsen, Niklas Beyersdorf, Sandra Werner, Nelli Wolf, Gabriele Köllner, Thomas Kerkau, Thomas Hünig
Publikováno v:
Journal of Neuroimmunology. 282:63-72
Targeting regulatory T cells (Treg cells) with interleukin-2 (IL-2) constitutes a novel therapeutic approach for autoimmunity. As anti-cancer therapy with IL-2 has revealed substantial toxicities a mutated human IL-2 molecule, termed AIC284 (formerly
Autor:
Carsten, Berges, Thomas, Kerkau, Sandra, Werner, Nelli, Wolf, Nadine, Winter, Thomas, Hünig, Hermann, Einsele, Max S, Topp, Niklas, Beyersdorf
Publikováno v:
Immunity, Inflammation and Disease
Introduction For many patients with leukemia only allogeneic bone marrow transplantion provides a chance of cure. Co‐transplanted mature donor T cells mediate the desired Graft versus Tumor (GvT) effect required to destroy residual leukemic cells.
Publikováno v:
European journal of immunology. 45(7)
Upon transplantation of T cells from a CD28 superagonist (CD28-SA) treated donor into an irradiated allogeneic host, the CD28-SA-induced activation and expansion of Treg cells inhibits acute graft versus host disease (aGvHD), while not abrogating the