Modular micro-physiological human tumor/tissue models based on decellularized tissue for improved preclinical testing

Autor: Kühnemundt J; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Leifeld H; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Scherg F; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Schmitt M; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Nelke LC; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Schmitt T; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Baur F; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research ISC, Würzburg, Germany., Göttlich C; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research ISC, Würzburg, Germany., Fuchs M; Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany., Kunz M; Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany.; Chair of Medical Informatics, Friedrich-Alexander University (FAU) of Erlangen-Nürnberg, Erlangen, Germany., Peindl M; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Brähler C; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Kronenthaler C; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany., Wischhusen J; University Hospital Würzburg, Department for Obstetrics & Gynecology, Section for Experimental Tumor Immunology, University of Würzburg, Würzburg, Germany., Prelog M; Children's University Hospital, Pediatric Rheumatology/Special Immunology, University of Würzburg, Würzburg, Germany., Walles H; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research ISC, Würzburg, Germany.; FVST, Core Facility Tissue Engineering, Otto-von Guericke University, Magdeburg, Germany., Dandekar T; Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany., Dandekar G; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research ISC, Würzburg, Germany., Nietzer SL; Department Tissue Engineering and Regenerative Medicine, University Hospital Würzburg, Würzburg, Germany.; Translational Center Regenerative Therapies, Fraunhofer Institute for Silicate Research ISC, Würzburg, Germany.

Publikováno v: ALTEX [ALTEX] 2020 Dec 11; Vol. 38 (2), pp. 289-306. Date of Electronic Publication: 2020 Dec 11.

Drug induced micellization into ultra-high capacity and stable curcumin nanoformulations: Physico-chemical characterization and evaluation in 2D and 3D in vitro models.

Autor: Lübtow MM; Functional Polymer Materials, Department of Chemistry and Pharmacy and Bavarian Polymer Institute, Würzburg University, Röntgenring 11, 97070 Würzburg, Germany., Nelke LC; University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany., Seifert J; University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany., Kühnemundt J; University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany., Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Collaborative Life Science Building, 2730 SW Moody Avenue, Portland, OR 97201, United States; Department of Biomedical Engineering, Oregon Health and Science University, Collaborative Life Science Building, 2730 SW Moody Avenue, Portland, OR 97201, United States., Dandekar G; University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany; Translational Center 'Regenerative Therapies' (TLC-RT), Fraunhofer Institute for Silicate Research (ISC), Neunerplatz 2, 97082 Würzburg, Germany., Nietzer SL; University Hospital Würzburg, Röntgenring 11, 97070 Würzburg, Germany. Electronic address: sarah.nietzer@uni-wuerzburg.de., Luxenhofer R; Functional Polymer Materials, Department of Chemistry and Pharmacy and Bavarian Polymer Institute, Würzburg University, Röntgenring 11, 97070 Würzburg, Germany. Electronic address: robert.luxenhofer@uni-wuerzburg.de.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2019 Jun 10; Vol. 303, pp. 162-180. Date of Electronic Publication: 2019 Apr 11.