Prospective antimicrobial stewardship interventions by multidisciplinary teams to reduce neonatal antibiotic use in South Africa: The Neonatal Antimicrobial Stewardship (NeoAMS) study

Autor: Angela Dramowski, Pavel Prusakov, Debra A. Goff, Adrian Brink, Nelesh P. Govender, Ama Sakoa Annor, Liezl Balfour, Adrie Bekker, Azraa Cassim, Michelle Gijzelaar, Sandi L. Holgate, Sonya Kolman, Angeliki Messina, Hafsah Tootla, Natalie Schellack, Andriette van Jaarsveld, Kessendri Reddy, Shakti Pillay, Lucinda Conradie, Anika M. van Niekerk, Tarina Bester, Pearl Alexander, Antoinette Andrews, Magdel Dippenaar, Colleen Bamford, Sharnel Brits, Pinky Chirwa, Hannelie Erasmus, Pieter Ekermans, Pebenita Gounden, Teresa Kriel, Dini Mawela, Masego Moncho, Tonia Mphuthi, Ronald Nhari, Esmita Charani, Pablo J. Sánchez, Dena van den Bergh

Publikováno v: International Journal of Infectious Diseases, Vol 146, Iss , Pp 107158- (2024)

Background: Hospitalized neonates are vulnerable to infection and have high rates of antibiotic utilization. Methods: Fourteen South African neonatal units (seven public, seven private sector) assembled multidisciplinary teams involving neonatologist

Externí odkaz: https://doaj.org/article/bfb98444969d45bd91d568ac1988fae6

Clinicopathological discrepancies in the diagnoses of childhood causes of death in the CHAMPS network: An analysis of antemortem diagnostic inaccuracies

Autor: Khatia Munguambe, Quique Bassat, Robert F Breiman, Mahbubur Rahman, Sibone Mocumbi, Cynthia G Whitney, Amy Wise, Shams El Arifeen, Meerjady Sabrina Flora, Soter Ameh, Emily S Gurley, Mustafizur Rahman, Ariel Nhacolo, Carla Carrilho, Cheick Bougadari Traore, Lucy Liu, Inacio Mandomando, Clara Menendez, Chris A Rees, Janet Agaya, Jane Juma, Tadesse Gure, George Aol, Hennie Lombaard, Ziyaad Dangor, Shabir Madhi, James Bunn, Samba O Sow, Dickson Gethi, Sanwarul Bari, Jeffrey P Koplan, Natalia Rakislova, Fabiola Fernandes, Tacilta Nhampossa, Maria Maixenchs, Mohammed Kamal, Nega Assefa, Joseph Oundo, Lola Madrid, Tahmina Shirin, Nelesh P Govender, Addisu Alemu, Hailemariam Legesse, Uma U Onwuchekwa, Awa Traore, Portia C Mutevedzi, Victor Akelo, Sammy Khagayi, Dickens Onyango, Richard Omore, Yasmin Adam, Peter Otieno, Margaret Mannah, Vicky Baillie, Karen L Kotloff, John Blevins, Milagritos D Tapia, Rima Koka, Mohammad Zahid Hossain, Dickens Kowuor, Tom Sesay, James Squire, Francis Moses, Haleluya Leulseged, Christine Bethencourt, Kitiezo Aggrey Igunza, Ikechukwu U Ogbuanu, Andrew Moseray, Ima-Abasi Bassey, Afruna Rahman, Muntasir Alam, Yasir Y Abdullahi, Nana Kourouma, Seydou Sissoko, Rosauro Varo, Sana Mahtab, Martin Hale, Jeanie du Toit, Zachary J Madewell, Dianna M Blau, Roosecelis B Martines, Fatima Solomon, Gillian Sorour, Jeannette Wadula, Karen Petersen, Peter J Swart, Sanjay G Lala, Sithembiso Velaphi, Richard Chawana, Ashleigh Fritz, Nellie Myburgh, Pedzisai Ndagurwa, Cleopas Hwinya, Shahana Parveen, ASM Nawshad Uddin Ahmed, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Ferdousi Begum K Zaman, Dilruba Ahmed, Alexander M Ibrahim, Fikremelekot Temesgen, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian MS Orlien, Solomon Ali, Peter Nyamthimba Onyango, Richard Oliech, Joyce Akinyi Were, Thomas Misore, Harun Owuor, Christopher Muga, Bernard Oluoch, Christine Ochola, Sharon M Tennant, Carol L Greene, Ashka Mehta, J Kristie Johnson, Brigitte Gaume, Adama Mamby Keita, Karen D Fairchild, Diakaridia Kone, Diakaridia Sidibe, Doh Sanogo, Kounandji Diarra, Tiéman Diarra, Kiranpreet Chawla, Zara Manhique, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, Alim Swaray-Deen, Joseph Bangura Amara Jambai, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Erick Kaluma, Oluseyi Balogun, Carrie Jo Cain, Solomon Samura, Samuel Pratt, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Francis Smart, Sartie Kenneh, Jana Ritter, Tais Wilson, Jonas Winchell, Jakob Witherbee, Navit T Salzberg, Margaret Basket, Ashutosh Wadhwa, Kyu Han Lee, Roosecelis Martines, Shamta Warang, Maureen Diaz, Jessica Waller, Shailesh Nair, Courtney Bursuc, Kristin LaHatte, Sarah Raymer, Solveig Argeseanu, Kurt Vyas, Manu Bhandari

Publikováno v: BMJ Paediatrics Open, Vol 8, Iss 1 (2024)

Introduction Determining aetiology of severe illness can be difficult, especially in settings with limited diagnostic resources, yet critical for providing life-saving care. Our objective was to describe the accuracy of antemortem clinical diagnoses

Externí odkaz: https://doaj.org/article/d37c6c24b1bb4fc5926b6da8646eb57d

Candida auris Clinical Isolates Associated with Outbreak in Neonatal Unit of Tertiary Academic Hospital, South Africa

Autor: Dikeledi Kekana, Serisha D. Naicker, Liliwe Shuping, Sithembiso Velaphi, Firdose L. Nakwa, Jeannette Wadula, Nelesh P. Govender

Publikováno v: Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2044-2053 (2023)

Candida auris was first detected at a university-affiliated hospital in Johannesburg, South Africa, in 2009. We used whole-genome sequencing to describe the molecular epidemiology of C. auris in the same hospital during 2016–2020; the neonatal unit

Externí odkaz: https://doaj.org/article/3532442e97cb4e94aacdcda0ce28dad4

Outbreak of NDM-1– and OXA-181–Producing Klebsiella pneumoniae Bloodstream Infections in a Neonatal Unit, South Africa

Autor: Rindidzani E. Magobo, Husna Ismail, Michelle Lowe, Wilhelmina Strasheim, Ruth Mogokotleng, Olga Perovic, Stanford Kwenda, Arshad Ismail, Manala Makua, Abram Bore, Rose Phayane, Harishia Naidoo, Tanya Dennis, Makhosazane Ngobese, Wim Wijnant, Nelesh P. Govender

Publikováno v: Emerging Infectious Diseases, Vol 29, Iss 8, Pp 1531-1539 (2023)

After an increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infections and associated deaths in the neonatal unit of a South Africa hospital, we conducted an outbreak investigation during October 2019–February 2020 and cross-

Externí odkaz: https://doaj.org/article/2dfdffa8925449f0b525f2c6fe11d037

Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) networkResearch in context

Autor: Chris A. Rees, Kitiezo Aggrey Igunza, Zachary J. Madewell, Victor Akelo, Dickens Onyango, Shams El Arifeen, Emily S. Gurley, Mohammad Zahid Hossain, Afruna Rahman, Muntasir Alam, J. Anthony G. Scott, Nega Assefa, Lola Madrid, Anteneh Belachew, Haleluya Leulseged, Karen L. Kotloff, Samba O. Sow, Milagritos D. Tapia, Adama Mamby Keita, Diakaridia Sidibe, Antonio Sitoe, Rosauro Varo, Sara Ajanovic, Quique Bassat, Inácio Mandomando, Beth A. Tippett Barr, Ikechukwu Ogbuanu, Carrie Jo Cain, Ima-Abasi Bassey, Ronita Luke, Khadija Gassama, Shabir Madhi, Ziyaad Dangor, Sana Mahtab, Sithembiso Velaphi, Jeanie du Toit, Portia C. Mutevedzi, Dianna M. Blau, Robert F. Breiman, Cynthia G. Whitney, Fatima Solomon, Gillian Sorour, Hennie Lombaard, Jeannette Wadula, Karen Petersen, Martin Hale, Nelesh P. Govender, Peter J. Swart, Sanjay G. Lala, Richard Chawana, Yasmin Adam, Amy Wise, Ashleigh Fritz, Nellie Myburgh, Pedzisai Ndagurwa, Cleopas Hwinya, Sanwarul Bari, Shahana Parveen, Mohammed Kamal, A.S.M. Nawshad Uddin Ahmed, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Ferdousi Begum, K. Zaman, Mustafizur Rahman, Dilruba Ahmed, Meerjady Sabrina Flora, Tahmina Shirin, Mahbubur Rahman, Joseph Oundo, Alexander M. Ibrahim, Fikremelekot Temesgen, Tadesse Gure, Addisu Alemu, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian Orlien, Solomon Ali, Peter Otieno, Peter Nyamthimba Onyango, Janet Agaya, Richard Oliech, Joyce Akinyi Were, Dickson Gethi, Sammy Khagayi, George Aol, Thomas Misore, Harun Owuor, Christopher Mugah, Bernard Oluoch, Christine Ochola, Sharon M. Tennant, Carol L. Greene, Ashka Mehta, J. Kristie Johnson, Brigitte Gaume, Rima Koka, Karen D. Fairchild, Diakaridia Kone, Doh Sanogo, Uma U. Onwuchekwa, Nana Kourouma, Seydou Sissoko, Cheick Bougadari Traore, Jane Juma, Kounandji Diarra, Awa Traore, Tiéman Diarra, Kiranpreet Chawla, Tacilta Nhampossa, Zara Manhique, Sibone Mocumbi, Clara Menéndez, Khátia Munguambe, Ariel Nhacolo, Maria Maixenchs, Andrew Moseray, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, James Bunn, Alim Swaray-Deen, Joseph Bangura, Amara Jambai, Margaret Mannah, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Dickens Kowuor, Erick Kaluma, Oluseyi Balogun, Solomon Samura, Samuel Pratt, Francis Moses, Tom Sesay, James Squire, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Hailemariam Legesse, Francis Smart, Sartie Kenneh, Soter Ameh, Jana Ritter, Tais Wilson, Jonas Winchell, Jakob Witherbee, Navit T. Salzberg, Jeffrey P. Koplan, Margaret Basket, Ashutosh Wadhwa, Kyu Han Lee, Valentine Wanga, Roosecelis Martines, Shamta Warang, Maureen Diaz, Jessica Waller, Shailesh Nair, Lucy Liu, Courtney Bursuc, Kristin LaHatte, Sarah Raymer, John Blevins, Solveig Argeseanu, Kurt Vyas, Manu Bhandari

Publikováno v: EClinicalMedicine, Vol 63, Iss , Pp 102198- (2023)

Summary: Background: Most childhood deaths globally are considered preventable through high-quality clinical care, which includes adherence to clinical care recommendations. Our objective was to describe adherence to World Health Organization recomme

Externí odkaz: https://doaj.org/article/7bbde38ed56a44c89b6d96f1be3aa920