Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Nele Vandersickel"'
Autor:
Arstanbek Okenov, Timur Nezlobinsky, Katja Zeppenfeld, Nele Vandersickel, Alexander V Panfilov
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300978 (2024)
Cardiac fibrosis stands as one of the most critical conditions leading to lethal cardiac arrhythmias. Identifying the precise location of cardiac fibrosis is crucial for planning clinical interventions in patients with various forms of ventricular an
Externí odkaz:
https://doaj.org/article/228843e38c0348f790a5d7a41b74bf65
Autor:
Robin Van Den Abeele, Sander Hendrickx, Enid Van Nieuwenhuyse, Albert Dunnink, Alexander V. Panfilov, Marc A. Vos, Eike M. Wülfers, Nele Vandersickel
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Torsade de Pointes is a polymorphic ventricular tachycardia which is as yet incompletely understood. While the onset of a TdP episode is generally accepted to be caused by triggered activity, the mechanisms for the perpetuation is still under debate.
Externí odkaz:
https://doaj.org/article/467a02e268dc436187235e4d4c72ce17
Autor:
Nele Vandersickel, Enid Van Nieuwenhuyse, Nico Van Cleemput, Jan Goedgebeur, Milad El Haddad, Jan De Neve, Anthony Demolder, Teresa Strisciuglio, Mattias Duytschaever, Alexander V. Panfilov
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Networks provide a powerful methodology with applications in a variety of biological, technological and social systems such as analysis of brain data, social networks, internet search engine algorithms, etc. To date, directed networks have not yet be
Externí odkaz:
https://doaj.org/article/a4552fcf30cf4d3f9cf98fa434111c99
Autor:
Nele Vandersickel, Masaya Watanabe, Qian Tao, Jan Fostier, Katja Zeppenfeld, Alexander V Panfilov
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006637 (2018)
Rotors are functional reentry sources identified in clinically relevant cardiac arrhythmias, such as ventricular and atrial fibrillation. Ablation targeting rotor sites has resulted in arrhythmia termination. Recent clinical, experimental and modelli
Externí odkaz:
https://doaj.org/article/f3b9e6ce75cf49b5b1fdc7aa83bfda1f
Autor:
Nele Vandersickel
Publikováno v:
The Project Repository Journal. 13:28-31
Cardiac arrhythmia There is an urgent need to better understand and localise the sources of cardiac arrhythmia in order to improve its treatment. In this project, we propose a radical new approach of applying network theory to study the mechanisms of
Autor:
Joshua Hawson, Enid Van Nieuwenhuyse, Robin Van Den Abeele, Ahmed Al-kaisey, Robert D. Anderson, David Chieng, Louise Segan, Troy Watts, Timothy Campbell, Sander Hendrickx, Joseph Morton, Alexander McLellan, Peter Kistler, Adam Lee, Edward P. Gerstenfeld, Henry H. Hsia, Aleksander Voskoboinik, Bhupesh Pathik, Saurabh Kumar, Jonathan Kalman, Geoffrey Lee, Nele Vandersickel
Publikováno v:
JACC: Clinical Electrophysiology.
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Early after depolarizations (EAD) occur in many pathological conditions, such as congenital or acquired channelopathies, drug induced arrhythmias, and several other situations that are associated with increased arrhythmogenicity. In this paper we pre
Externí odkaz:
https://doaj.org/article/b7f2871c5bc640048197b0a12d74b80d
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188867 (2017)
Early Afterdepolarizations, EADs, are defined as the reversal of the action potential before completion of the repolarization phase, which can result in ectopic beats. However, the series of mechanisms of EADs leading to these ectopic beats and relat
Externí odkaz:
https://doaj.org/article/d80b9ebc54554cc9bd22ce562bca6aac
Autor:
Enid Van Nieuwenhuyse, Sander Hendrickx, Robin Van den Abeele, Bharathwaj Rajan, Lars Lowie, Sebastien Knecht, Mattias Duytschaever, Nele Vandersickel
Publikováno v:
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
In this work, we present the release of a novel easy to use software package called DGM or Directed-Graph-Mapping. DGM can automatically analyze any type of arrhythmia to find reentry or focal sources if the measurements are synchronized in time. Cur
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130632 (2015)
Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes. We carry out extensive numeric
Externí odkaz:
https://doaj.org/article/5db1f517252f45c5bd8b5d16e7bcd676