Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nele Goeyvaerts"'
Autor:
Clare P McCormack, Olivia Goethals, Nele Goeyvaerts, Xavier D Woot de Trixhe, Peggy Geluykens, Doortje Borrenberghs, Neil M Ferguson, Oliver Ackaert, Ilaria Dorigatti
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011662 (2023)
Dengue virus (DENV) is a public health challenge across the tropics and subtropics. Currently, there is no licensed prophylactic or antiviral treatment for dengue. The novel DENV inhibitor JNJ-1802 can significantly reduce viral load in mice and non-
Externí odkaz:
https://doaj.org/article/c7b81f83b8a542829af76be3e64ed51d
Autor:
Louis, Sandra, Huybrecht, T'jollyn, Nele, Goeyvaerts, An, Vermeulen, Anne-Gaëlle, Dosne, Juan-Jose, Perez-Ruixo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:70-79
JNJ-73763989 is an N-acetylgalactosamine conjugated short interfering RNA combination product consisting of two triggers in clinical development for chronic hepatitis B virus (HBV) infection treatment that induces a selective degradation of all HBV m
Autor:
Anne-Gaëlle Dosne, Elodie Valade, Nele Goeyvaerts, Peter De Porre, Anjali Avadhani, Anne O’Hagan, Lilian Y. Li, Daniele Ouellet, Juan Jose Perez Ruixo
Publikováno v:
Cancer Chemotherapy and Pharmacology. 89:151-164
Background Exposure–response analyses were conducted to explore the relationship between selected efficacy and safety endpoints and serum phosphate (PO4) concentrations, a potential biomarker of efficacy and safety, in locally advanced or metastati
Autor:
Nele Goeyvaerts, Lander Willem, Kim Van Kerckhove, Yannick Vandendijck, Germaine Hanquet, Philippe Beutels, Niel Hens
Publikováno v:
Epidemics, Vol 13, Iss C, Pp 1-9 (2015)
Dynamic transmission models are essential to design and evaluate control strategies for airborne infections. Our objective was to develop a dynamic transmission model for seasonal influenza allowing to evaluate the impact of vaccinating specific age
Externí odkaz:
https://doaj.org/article/e01bb51b93ca4de49069b6cc26c8d03a
Autor:
Yimer Wasihun Kifle, Nele Goeyvaerts, Kim Van Kerckhove, Lander Willem, Adam Kucharski, Christel Faes, Herwig Leirs, Niel Hens, Philippe Beutels
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148718 (2016)
Externí odkaz:
https://doaj.org/article/7dca95327b5c4568ae82ba01bbff23f6
Autor:
Liviawati S Wu, Yue Hu, Edward J Gane, Leen Slaets, An De Creus, Yanhua Ding, Junqi Niu, Christian Schwabe, Nele Goeyvaerts, Zhongnan Xu, Dandan Huo, Marianne Tuefferd, Inge Verbrugge, Pieter Van Remoortere, Ullrich Schwertschlag, Joris Vandenbossche
Publikováno v:
Antiviral Therapy. 28:135965352311516
Background JNJ-4964 is a TLR7 agonist, which, via a type I interferon (IFN)–dependent mechanism, may enhance host immunity suppressed by persistent exposure to hepatitis B antigens in chronic hepatitis B. Methods PK and PD data were pooled from 2 s
Autor:
Huybrecht T’jollyn, Nele Goeyvaerts, Thomas Kakuda, Louis Sandra, Tetsuro Ogawa, Joris J Vandenbossche, Xavier Woot de Trixhe, Oliver Lenz, Ronald Kalmeijer, Michael Biermer, Juan Jose Perez Ruixo, Oliver Ackaert
Publikováno v:
Journal of Hepatology. 77:S838-S839
Autor:
Yimer Wasihun Kifle, Nele Goeyvaerts, Kim Van Kerckhove, Lander Willem, Adam Kucharski, Christel Faes, Herwig Leirs, Niel Hens, Philippe Beutels
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133461 (2015)
Many human infectious diseases originate from animals or are transmitted through animal vectors. We aimed to identify factors that are predictive of ownership and touching of animals, assess whether animal ownership influences social contact behavior
Externí odkaz:
https://doaj.org/article/f2ad0be4a5d34657bd4d56d84ce84e88
Autor:
Carlos G Grijalva, Nele Goeyvaerts, Hector Verastegui, Kathryn M Edwards, Ana I Gil, Claudio F Lanata, Niel Hens, RESPIRA PERU project
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118457 (2015)
Few studies have quantified social mixing in remote rural areas of developing countries, where the burden of infectious diseases is usually the highest. Understanding social mixing patterns in those settings is crucial to inform the implementation of
Externí odkaz:
https://doaj.org/article/71208bff81ad46d48db4a21ede85c083
Autor:
Ed Gane, Man-Fung Yuen, Thomas N Kakuda, Tetsuro Ogawa, Yasushi Takahashi, Nele Goeyvaerts, Isabelle Lonjon-Domanec, Tamisha Vaughan, Thomas Schluep, James Hamilton, Emmanuel Njumbe Ediage, Vera Hillewaert, Jan Snoeys, Oliver Lenz, Willem Talloen, Michael Biermer
Publikováno v:
Antiviral Therapy. 27:135965352210938
Background JNJ-73763989 comprises two hepatitis B virus (HBV)-specific, liver-targeted N-galactosamine-conjugated short interfering RNA triggers, JNJ-73763976 and JNJ-73763924. JNJ-73763989 pharmacokinetics, safety and tolerability were assessed in t