Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nele Evens"'
Autor:
Zeger Debyser, Giulio G. Muccioli, Caroline Vandeputte, Nele Evens, Didier M. Lambert, Guy Bormans, Alfons Verbruggen, Koen Van Laere, Veerle Baekelandt
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4499-4505
The type 2 cannabinoid receptor (CB₂R) is part of the endocannabinoid system and is expressed in tissues related to the immune system. As the CB₂R has a very low brain expression in non-pathological conditions, but is upregulated in activated mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a224f8d84d0e30bd3281c904271971
https://doi.org/10.1016/j.bmc.2011.06.033
https://doi.org/10.1016/j.bmc.2011.06.033
Autor:
Caroline Vandeputte, Nele Evens, Barbara Bosier, Jaan Toelen, Abdelilah Ibrahimi, Rik Gijsbers, Guy Bormans, Didier M. Lambert, Peter Janssen, Alfons Verbruggen, Christophe Deroose, Koen Van Laere, Zeger Debyser, Veerle Baekelandt, Anke Van der Perren
Publikováno v:
Journal of Nuclear Medicine. 52:1102-1109
PET of gene expression in the brain may greatly facilitate neuroscience research and potential clinical implementation of gene or cell therapy of central nervous system diseases. To date, no adequate PET reporter system is available for the central n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b45b1429bf23bf8163d2d5f9321d8ba
https://doi.org/10.2967/jnumed.110.084426
https://doi.org/10.2967/jnumed.110.084426
Autor:
Nele Evens, Guy Bormans, Giulio G. Muccioli, Didier M. Lambert, Koen Van Laere, Alfons Verbruggen, Nele Houbrechts
Publikováno v:
Nuclear Medicine and Biology. 36:455-465
Introduction: The type 2 cannabinoid (CB2) receptor is part of the endocannabinoid system and has been Suggested as a mediator of several central and peripheral inflammatory processes. Imaging of the CB2 receptor has been unsuccessful so far. We synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5279d8cc432b4cfedf8729b9d31af3
https://doi.org/10.1016/j.nucmedbio.2009.01.009
https://doi.org/10.1016/j.nucmedbio.2009.01.009
Autor:
Luc Baudemprez, Roger Busson, Alfons Verbruggen, Nele Evens, Barbara Bosier, Didier M. Lambert, Brian J. Lavey, Guy Bormans, Joseph A. Kozlowski, Koen Van Laere, Peter Vermaelen
Publikováno v:
Nuclear Medicine and Biology. 35:793-800
Introduction: The cannabinoid type 2 receptor (CB2 receptor) is part of the endocannabinoid system and has been suggested as mediator of a number of central and peripheral inflammatory processes. In the present Study, we have synthesized N-[(Is)-I-[4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff996b3e6260c3fec3112ca4641bcf85
https://doi.org/10.1016/j.nucmedbio.2008.07.004
https://doi.org/10.1016/j.nucmedbio.2008.07.004
Autor:
Satish K. Chitneni, Lucette Garreau, Guy Bormans, Alfons Verbruggen, Denis Guilloteau, Nele Evens, Sylvie Chalon, B. Cleynhens, Koen Van Laere, Peter Vermaelen, Marva Bex, Roger Busson
Publikováno v:
Nuclear Medicine and Biology. 35:75-82
Introduction [2′-[ 18 F]Fluoroethyl (lR-2-exo-3-exe)-8-methyl-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]-octane-2-carboxylate] ([ 18 F]FECT) is a positron emission tomography (PET) tracer for imaging the dopamine transporter (DAT) in vivo. We report an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c547ca2005e9c951c1589c19894d6b
https://doi.org/10.1016/j.nucmedbio.2007.09.001
https://doi.org/10.1016/j.nucmedbio.2007.09.001
Autor:
Hubert Vanbilloen, Guy Bormans, Dirk Rattat, Nele Evens, Alfons Verbruggen, K Eraets, C Terwinghe, Luc Mortelmans
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:1003-1011
Three cyclic polyamines, namely 1,4,7-triazacyclononane, 1,4,7,10-tetraazacyclo-dodecane (cyclen) and 1,4,8,11-tetraazacyclotetradecane (cyclam), were evaluated as potential ligands for complexation of a technetium(I) tricarbonyl core. They can be us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a3d4c46f9c84440e2a8939ce6a67da
https://doi.org/10.1002/jlcr.1012
https://doi.org/10.1002/jlcr.1012
Autor:
Caroline Vandeputte, Nele Evens, Alfons Verbruggen, Peter Janssen, Raf Sciot, Koen Van Laere, Charlotte Coolen, Guy Bormans, Zeger Debyser, Veerle Baekelandt
Publikováno v:
Nuclear medicine and biology. 39(3)
Introduction Up-regulation of the type 2 cannabinoid receptor (CB 2 R) has been reported in (neuro)inflammatory diseases. In this study, we report the preclinical evaluation of [ 11 C]NE40 as positron emission tomography (PET) radioligand for visuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba82e435f836bf28b3ed807e67a47f7
https://pubmed.ncbi.nlm.nih.gov/22154685
https://pubmed.ncbi.nlm.nih.gov/22154685
Autor:
Guy Bormans, Nele Evens
Publikováno v:
Current topics in medicinal chemistry. 10(15)
The type 2 cannabinoid receptor (CB(2)R) is a relatively new target for drug development, as the receptor was only discovered in 1993. The CB(2)R is mainly expressed in tissues and organs related to the immune system. However, in pathological conditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a522b7ded34399c27e6bbc781530ab6b
https://pubmed.ncbi.nlm.nih.gov/20583994
https://pubmed.ncbi.nlm.nih.gov/20583994
Autor:
Nele Evens, Guy Bormans, Alfons Verbruggen, Kim Serdons, Satish K. Chitneni, Sofie Celen, Zeger Debyser, Humphrey Fonge, Christophe Deroose, Luc Mortelmans
Publikováno v:
Journal of chromatography. A. 1189(1-2)
This study describes an efficient method using on-line solid-phase extraction (SPE) (Oasis® HLB) for preparative HPLC purification of short-lived radiotracers for positron emission tomography (PET) and for HPLC analysis of radiotracers and their met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510ae81cc7d7000fd0bcd1e6c6344aed
https://pubmed.ncbi.nlm.nih.gov/18045609
https://pubmed.ncbi.nlm.nih.gov/18045609
Autor:
Michel Koole, Kim Serdons, Alfons Verbruggen, Nele Evens, Guy Bormans, Rawaha Ahmad, Koen Van Laere
Publikováno v:
Molecular Imaging and Biology
PURPOSE:The type 2 cannabinoid receptor (CB2R) is part of the human endocannabinoid system and is involved in central and peripheral inflammatory processes. In vivo imaging of the CB2R would allow study of several (neuro)inflammatory disorders. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4737cded3439f2d877a1f9a78c43a26d
