Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nel Willekes-Koolschijn"'
Autor:
Branko Braam, Nel Willekes-Koolschijn, Hein A. Koomans, Thi Danh Vuong, Peter Boer, Jaap A. Joles
Publikováno v:
Nephrology Dialysis Transplantation. 18:1485-1492
BACKGROUND Lysophosphatidylcholine (LPC) causes vascular dysfunction in vitro. Lipoprotein LPC is increased in hypoalbuminaemia. Albumin binds LPC and restores LPC-induced abnormalities. We hypothesized that in vivo LPC impairs blood flow more in hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb8626ae4989693ee39d4013d460f73
https://doi.org/10.1093/ndt/gfg238
https://doi.org/10.1093/ndt/gfg238
Autor:
Jaap A. Joles, Eric S G Stroes, Nel Willekes-Koolschijn, Ton J. Rabelink, Thi Danh Vuong, Hein A. Koomans
Publikováno v:
Kidney International. 55(3):1005-1010
Hypoalbuminemia increases lysophosphatidylcholine in low-density lipoprotein of normocholesterolemic subjects.BackgroundA phospholipid, lysophosphatidylcholine (LPC), is the major determinant of the atherosclerotic properties of oxidized low-density
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5bf54d2cb623e4181fefed0fab12f1
Autor:
Arie van Tol, Jaap A. Joles, Eugène H.J.M. Jansen, Harry van Goor, Branko Braam, Hein A. Koomans, Nel Willekes-Koolschijn
Publikováno v:
Kidney International. 47(2):442-453
To elucidate the pathogenetic role of hyperlipidemia per se in the development of glomerulosclerosis, severely hyperlipidemic female analbuminemic rats (NAR) and mildly hyperlipidemic male NAR were studied for a period of 37 weeks after uninephrectom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0ec2e4e3ecb81dffe3789692da63f2
Autor:
Daan J.A. Crommelin, Louis van Bloois, Louis H. Cohen, Nel Willekes-Koolschijn, Hein A. Koomans, Magda Krajnc-Franken, Arie van Tol, Jaap A. Joles, Willem Erkelens, Marieke Griffioen, Tini Geelhoed-Mieras
Publikováno v:
Laboratory Animals. 26:269-280
Recent reports demonstrate a hypocholesterolaemic effect of daily subcutaneous injections of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in different rat models of hyperlipidaemia. However, this effect is not seen after oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5113c32f9487f9bd54fd728fc4b7ddcb
https://doi.org/10.1258/002367792780745689
https://doi.org/10.1258/002367792780745689
Autor:
Hendrik A. Koomans, W. Kortlandt, E. van Garderen, D.W. Erkelens, A. van Tol, L.H.J.C. Danse, J. A. Joles, Nel Willekes-Koolschijn, M.M. Geelhoed-Mieras
Publikováno v:
Atherosclerosis. 88(1)
Plasma lipoprotein distribution and apolipoprotein concentrations, as well as kidney function and histopathology of heart, aorta, liver and kidney were investigated in 1-year-old Nagase analbuminemic rats (NAR) and control Sprague-Dawley rats (SDR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3916e9bf894ae6b12ca881215c352a5
https://pubmed.ncbi.nlm.nih.gov/1878008
https://pubmed.ncbi.nlm.nih.gov/1878008
Autor:
J. A. Joles, E. H. J. M. Jansen, Nel Willekes-Koolschijn, Hendrik A. Koomans, W. Kortlandt, C. A. Laan
Publikováno v:
British Journal of Nutrition. 61:485-494
1. Analbuminaemic and Sprague-Dawley (control) rats were fed on low- (60 g/kg) protein and control (200 g protein/kg) dietsad lib.from weaning. Males and females were studied separately. Body-weight and plasma protein concentrations were determined a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad7ed84dc87769df483f41f36f611f2
https://doi.org/10.1079/bjn19890138
https://doi.org/10.1079/bjn19890138
Autor:
Ton J. Rabelink, Nel Willekes-Koolschijn, Jaap A. Joles, Hein A. Koomans, L.M. Scheek, Arie van Tol
Publikováno v:
Kidney International. (1):97-104
Lipoprotein phospholipid composition and LCAT activity in nephrotic and analbuminemic rats. Albumin is an acceptor of lysophosphatidyl-choline (LPC), product of the lecithinxholesterol acyl transferase (LCAT) reaction, and it has been suggested that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bcbf083078d3cf8a38024ad8745575
Publikováno v:
Kidney International. (3):761-770
Hypoalbuminemia causes high blood viscosity by increasing red cell lysophosphatidylcholine. Albumin deficiency is accompanied by a reduction in red cell deformability and blood hyperviscosity. Albumin deficiency increases plasma fibrinogen and trigly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4faa4f5ce085d80db46234a32dc975d9
Autor:
Nel Willekes-Koolschijn, Hendrik A. Koomans, J. A. Joles, W. Kortlandt, Branko Braam, E. J. Dorhout Mees
Publikováno v:
The American journal of physiology. 257(1 Pt 2)
Colloid osmotic pressure (COP) was measured in plasma and interstitial fluid (subcutaneous wick) from 8 to 75 days of age in Nagase analbuminemic rats (NAR) and control Sprague-Dawley rats (SDR). In all animals plasma COP (approximately 10 mmHg at 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a5c3bc2a55a1be22c686c1150e5618
https://pubmed.ncbi.nlm.nih.gov/2750922
https://pubmed.ncbi.nlm.nih.gov/2750922