Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Nel C. MOORE"'
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Study of the interaction of the medium chain μ2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28
Autor: Emily R. FOLLOWS, Jane C. McPHEAT, Claire MINSHULL, Nel C. MOORE, Richard A. PAUPTIT, Siân ROWSELL, Claire L. STACEY, Judith J. STANWAY, Ian W. F. TAYLOR, W. Mark ABBOTT
Publikováno v: Biochemical Journal. 359:427-434
The medium chain μ2 subunit (AP50) of the clathrin-associated adapter protein complex 2 (AP-2) interacts specifically with the tyrosine-based signals of several integral membrane proteins through the consensus sequence YXXΦ, where X can be any resi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d46275747f032ca95c73aa5b71a04656
https://doi.org/10.1042/bj3590427
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3
Positive Selection by Purified MHC Class II / Thymic Epithelial Cells In Vitro: Costimulatory Signals Mediated by B7 Are Not Involved
Autor: Graham Anderson, John J. T. Owen, Eric J. Jenkinson, Nel C. Moore, Christopher A. Smith
Publikováno v: Clinical and Developmental Immunology, Vol 3, Iss 4, Pp 265-271 (1994)
Developmental Immunology
We have investigated the possibility that the costimulatory signals required for activation of mature T cells also play a role in providing differentiation signals for positive selection during T-cell development. We show that purified MHC Class II+t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a7f78aa249e15b491aeff9c2ca7803
https://doaj.org/article/3885756616b945a9931d9a2210c66cd7
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4
Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro
Autor: Eric J. Jenkinson, Graham Anderson, Nel C. Moore, John J. T. Owen
Publikováno v: The Journal of Experimental Medicine
Using a novel system that supports positive selection in vitro, we have investigated the cellular requirements for this process by testing the ability of individual thymic and nonthymic stromal cell types to support the maturation of CD4+CD8+ thymocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aace212900555f8556e87e7229ac6af3
http://europepmc.org/articles/PMC2191508
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5
Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction
Autor: Eric J. Jenkinson, Graham Anderson, Nel C. Moore, Christopher A. Smith, John J. T. Owen
Publikováno v: European Journal of Immunology. 23:922-927
Using a semi-quantitative polymerase chain reaction (PCR) technique we have examined the expression of a panel of cytokines during thymus development, localizing the expression to individual components of the thymic stroma and thymocytes at different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1f099e8ffe0460a5676d48f7decadb
https://doi.org/10.1002/eji.1830230424
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6
Effects of intraperitoneal administration of hexasodium N,N,N?,N?-ethylenediaminetetramethylenephosphonate on rat bone metabolism
Autor: James K. Chipman, Nel C. Moore
Publikováno v: Fundamental and Applied Toxicology. 14:491-501
The influence of hexasodium N,N,N′,N′ -ethylenediaminetetramethylenephosphonate (EDITEMP.Na 6 ) on biochemical parameters in bone has been studied to help explain recently reported histological and pathological changes in bone induced by this age
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1d3922294929e86dedab17cf8abbb7
https://doi.org/10.1016/0272-0590(90)90253-g
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7
Direct modulatory effect of hexasodium N,N,N′,N′-ethylenediamine-tetramethylenephosphonate on bone cell function in vitro
Autor: James K. Chipman, Nel C. Moore
Publikováno v: Bone and Mineral. 8:157-168
The phosphonate hexasodium N,N,N′,N′ -ethylenediamine-tetramethylenephosphonate (EDITEMP · Na 6 ) reduced alkaline phosphatase (Alp) activity and cAMP response to parathyroid hormone (PTH) in primary cultures of foetal rat calvaria cells in a do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bad813aef46c981cbc949ce3fdf89ed
https://doi.org/10.1016/0169-6009(90)90118-y
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9
Intrathymic expression of genes involved in organ specific autoimmune disease
Autor: Sonia M. Parnell, Victoria L. Heath, Nel C. Moore, Don Mason
Publikováno v: Journal of autoimmunity. 11(4)
Insulin, thyroglobulin and myelin basic protein (MBP) are implicated as autoantigens in the autoimmune diseases, insulin-dependent diabetes mellitus (IDDM), autoimmune thyroid-disease and multiple sclerosis. Self tolerance to these antigens, until re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5364ef971335079fefecdb5e773fc707
https://pubmed.ncbi.nlm.nih.gov/9776708
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10
Studies on thymic epithelial cells in vitro
Autor: Kim L. Anderson, Eric J. Jenkinson, John J. T. Owen, Nel C. Moore, Deirdre E.J. McLoughlin
Publikováno v: Developmental and comparative immunology. 22(3)
Thymic epithelial cells are unique in their ability to support positive selection and are essential throughout thymocyte development. Here, we describe a technique for measuring the proliferation of thymic epithelial cells by flow cytometry using a c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a201177edec5186ce8b9a8a1a124928f
https://pubmed.ncbi.nlm.nih.gov/9700465
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