Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Nektarios Oraiopoulos"'
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Thousands of biotech companies are developing promising products, but have insufficient resources to complete the clinical testing process, while large, well-funded companies have increasingly focused on the need to access external innovation. As a r
Externí odkaz:
https://doaj.org/article/f4bb98ac7c1145eca64570d0d27aa3bb
Autor:
Vishal Agrawal, Nektarios Oraiopoulos
Publikováno v:
Manufacturing & Service Operations Management. 22:832-849
Problem definition: How should decision rights be allocated between firms occupying different positions in the value chain to maximize the value of a codevelopment project? Academic/practical relevance: We contribute to the operations management lite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae461fa7b7d787cda99b9185e49c0bee
https://doi.org/10.1287/msom.2019.0775
https://doi.org/10.1287/msom.2019.0775
Publikováno v:
California Management Review. 62:42-63
This article develops a framework for driving innovation under highly ambiguous conditions. An analysis of the most novel medicines of the past 20 years shows that a very large group of small companies created more breakthroughs, at considerably less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93e0f78e1a7d0e78caac57173e6f7ac5
https://doi.org/10.1177/0008125620915289
https://doi.org/10.1177/0008125620915289
This chapter offers an overview of the major scientific advances that led to the founding of the biotech industry in the 1970s. While the first entrepreneurial life-sciences companies were established primarily to take advantage of rDNA and monoclona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e83d8096c771112b139230a2f5c0250
https://doi.org/10.1093/oso/9780195084009.003.0002
https://doi.org/10.1093/oso/9780195084009.003.0002
This chapter explores how new medicines are created. It describes the principal steps, the regulatory framework, and the various elements that contribute to the cost of the drug development process. Astronomical amounts of money are required for a bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2e19ac21fb2d9ebba55efeb017473a
https://doi.org/10.1093/oso/9780195084009.003.0003
https://doi.org/10.1093/oso/9780195084009.003.0003
This chapter focuses on how biotechnology companies are founded and the process by which they raise funds. Developing new pharmaceutical products is incredibly expensive, so the search for a continuing supply of cash resources has been an essential c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21eb71257ce1d9bb4bda6c5d2422a52
https://doi.org/10.1093/oso/9780195084009.003.0004
https://doi.org/10.1093/oso/9780195084009.003.0004
This chapter introduces the biotechnology industry, tracks its growth from its origins in the 1970s to the present, and presents topline results of its track record. That record shows that the biotech industry has created more innovative medicines at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::765fdc3068e1654d7ffdab5f5d7c8e0e
https://doi.org/10.1093/oso/9780195084009.003.0001
https://doi.org/10.1093/oso/9780195084009.003.0001
This chapter explores whether today’s approach to innovative drug discovery will continue. The governments that invest over $100 billion a year in fundamental research do so with the dual goal of promoting the health of their citizens through the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b946d5b810393803172004390c254525
https://doi.org/10.1093/oso/9780195084009.003.0008
https://doi.org/10.1093/oso/9780195084009.003.0008
Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize–winning discoveries, the biotech industry grew to thousands of small companies arou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a1ee1f28da7962f4de36ad34eb126c
https://doi.org/10.1093/oso/9780195084009.001.0001
https://doi.org/10.1093/oso/9780195084009.001.0001